Patents by Inventor T. Bruce Ferguson, Jr.
T. Bruce Ferguson, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230052746Abstract: A method to visualize, display, analyze and quantify angiography, perfusion, and the change in angiography and perfusion in real time, is provided. This method captures image data sequences from indocyanine green near infra-red fluorescence imaging used in a variety of surgical procedure applications, where angiography and perfusion are critical for intraoperative decisions.Type: ApplicationFiled: March 28, 2022Publication date: February 16, 2023Applicant: Stryker European Operations LimitedInventors: T. Bruce FERGUSON, JR., Cheng CHEN
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Patent number: 11564583Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: GrantFiled: November 16, 2020Date of Patent: January 31, 2023Assignee: Stryker European Operations LimitedInventors: Peter Dvorsky, David Mark Henri Goyette, T. Bruce Ferguson, Jr., Cheng Chen
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Patent number: 11284801Abstract: A method to visualize, display, analyze and quantify angiography, perfusion, and the change in angiography and perfusion in real time, is provided. This method captures image data sequences from indocyanine green near infra-red fluorescence imaging used in a variety of surgical procedure applications, where angiography and perfusion are critical for intraoperative decisions.Type: GrantFiled: March 18, 2019Date of Patent: March 29, 2022Assignee: Stryker European Operations LimitedInventors: T. Bruce Ferguson, Jr., Cheng Chen
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Patent number: 11278220Abstract: Some embodiments of the present inventive concept provide a multispectral imaging system including a first light source, the first light source having a first wavelength configured to produce a non-coherent illumination to image a sample; a second coherent light source, different from the first light source, having a second wavelength, different from the first wavelength, configured to image the sample simultaneously with the first light source; a camera configured to simultaneously receive information related to the first and second light sources from the sample, wherein light at the first wavelength is configured to image a surface of the sample into the camera and light at the second wavelength is configured to penetrate the sample and provide information related to the penetrated sample to the camera; and a processor configured to combine the received information related to the first and second light sources and generate a synthesized image of the anatomical structure and the physiology of blood flow andType: GrantFiled: June 6, 2019Date of Patent: March 22, 2022Assignee: East Carolina UniversityInventors: Bryent Tucker, T. Bruce Ferguson, Jr., Cheng Chen
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Publication number: 20210169354Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: ApplicationFiled: November 16, 2020Publication date: June 10, 2021Applicant: Stryker European Operations LimitedInventors: Peter DVORSKY, David Mark Henri GOYETTE, T. Bruce FERGUSON, JR., Cheng CHEN
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Patent number: 10948350Abstract: Multispectral imaging systems are provided including an illumination control module configured to image a sample and provide an imaging output sequence including images and data; a multi-spectral physiologic visualization (MSPV) module, a peripheral oxygen saturation (SpO2) module and a physiologic status parameters (PSP) module configured to receive the imaging output sequence of the illumination control module simultaneously. The MSPV module is configured to provide real-time blood flow distribution visualization of a field of view (FOV) responsive to the received imaging output sequence. The SpO2 module is configured to provide real-time SpO2 information at a tissue surface level for the FOV responsive to the received imaging and output sequence. The PSP module is configured to derive status parameters in real-time from metadata associated with the received imaging and output sequence of the FOV.Type: GrantFiled: September 4, 2019Date of Patent: March 16, 2021Assignee: East Carolina UniversityInventors: T. Bruce Ferguson, Jr., Bryent Tucker, Sunghan Kim, Cheng Chen, William Hempstead
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Patent number: 10835138Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: GrantFiled: April 6, 2018Date of Patent: November 17, 2020Assignee: Stryker European Operations LimitedInventors: Peter Dvorsky, David Mark Henri Goyette, T. Bruce Ferguson, Jr., Cheng Chen
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Publication number: 20200072670Abstract: Multispectral imaging systems are provided including an illumination control module configured to image a sample and provide an imaging output sequence including images and data; a multi-spectral physiologic visualization (MSPV) module, a peripheral oxygen saturation (SpO2) module and a physiologic status parameters (PSP) module configured to receive the imaging output sequence of the illumination control module simultaneously. The MSPV module is configured to provide real-time blood flow distribution visualization of a field of view (FOV) responsive to the received imaging output sequence. The SpO2 module is configured to provide real-time SpO2 information at a tissue surface level for the FOV responsive to the received imaging and output sequence. The PSP module is configured to derive status parameters in real-time from metadata associated with the received imaging and output sequence of the FOV.Type: ApplicationFiled: September 4, 2019Publication date: March 5, 2020Inventors: T. Bruce Ferguson, Jr., Bryent Tucker, Sunghan Kim, Cheng Chen, William Hempstead
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Publication number: 20190374106Abstract: A method to visualize, display, analyze and quantify angiography, perfusion, and the change in angiography and perfusion in real time, is provided. This method captures image data sequences from indocyanine green near infra-red fluorescence imaging used in a variety of surgical procedure applications, where angiography and perfusion are critical for intraoperative decisions.Type: ApplicationFiled: March 18, 2019Publication date: December 12, 2019Applicant: Novadaq Technologies ULCInventors: T. Bruce FERGUSON, JR., Cheng CHEN
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Patent number: 10390718Abstract: Multispectral imaging systems are provided including a first light source having a first wavelength configured to image a sample; a second light source, different from the first light source, having a second wavelength, different from the first wavelength, configured to image the sample; and at least a third light source, different from the first and second light sources, having a third wavelength, different from the first and second wavelengths, configured to image the sample. A camera is configured to receive information related to the first, second and at least third light sources from the sample. A processor is configured to combine the information related to the first, second and at least third light sources provided by the camera to image an anatomical structure of the sample, image physiology of blood flow and perfusion of the sample and/or synthesize the anatomical structure and the physiology of blood flow and perfusion of the sample in terms of a blood flow rate distribution.Type: GrantFiled: August 28, 2017Date of Patent: August 27, 2019Assignee: East Carolina UniversityInventors: Cheng Chen, T. Bruce Ferguson, Jr., Kenneth Michael Jacobs
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Patent number: 10278585Abstract: A method to visualize, display, analyze and quantify angiography, perfusion, and the change in angiography and perfusion in real time, is provided. This method captures image data sequences from indocyanine green near infra-red fluorescence imaging used in a variety of surgical procedure applications, where angiography and perfusion are critical for intraoperative decisions.Type: GrantFiled: June 20, 2013Date of Patent: May 7, 2019Assignee: NOVADAQ TECHNOLOGIES ULCInventors: T. Bruce Ferguson, Jr., Cheng Chen
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Publication number: 20190086198Abstract: Methods, systems and computer program products are provided for determining parameters during a surgical procedure. A plurality of patterns are projected onto an object plane associated with a target to be imaged. The plurality of patterns are manipulated such that the plurality of patterns overlap at a common point indicating a proper object distance from the target to be imaged.Type: ApplicationFiled: September 21, 2016Publication date: March 21, 2019Inventors: Cheng Chen, Zhiyong Peng, Kenneth Michael Jacobs, T. Bruce Ferguson, JR.
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Publication number: 20180337507Abstract: A fiber assembly is provided including a laser input end configured to receive an input signal having a first laser beam intensity. The fiber assembly further includes a plurality of channels attached to the laser input end and a plurality of laser safety adaptors. Each of the plurality of laser safety adaptors is configured to receive a corresponding one of the plurality of channels. A laser beam exiting each of the plurality of laser safety adaptors has a second laser beam intensity that is less than the first laser beam intensity.Type: ApplicationFiled: March 24, 2016Publication date: November 22, 2018Inventors: Zhiyong Peng, T. Bruce Ferguson, JR., Cheng Chen, Kenneth Michael Jacobs
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Patent number: 10058256Abstract: Some embodiments of the present inventive concept provide a system that uses two wavelengths of differential transmittance through a sample to apply laser speckle or laser Doppler imaging. A first of the two wavelengths is within the visible range that has zero or very shallow penetration. This wavelength captures the anatomical structure of tissue/organ surface and serves as a position marker of the sample but not the subsurface movement of blood flow and perfusion. A second wavelength is in the near Infra-Red (NIR) range, which has much deeper penetration. This wavelength reveals the underlying blood flow physiology and correlates both to the motion of the sample and also the movement of blood flow and perfusion. Thus, true motion of blood flow and perfusion can be derived from the NIR imaging measurement without being affected by the motion artifact of the target.Type: GrantFiled: February 26, 2016Date of Patent: August 28, 2018Assignee: East Carolina UniversityInventors: Cheng Chen, T. Bruce Ferguson, Jr., Zhiyong Peng, Kenneth Michael Jacobs
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Publication number: 20180220907Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: ApplicationFiled: April 6, 2018Publication date: August 9, 2018Applicant: Novadaq Technologies ULCInventors: Peter DVORSKY, David Mark Henri GOYETTE, T. Bruce FERGUSON, JR., Cheng CHEN
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Patent number: 9936887Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: GrantFiled: March 31, 2017Date of Patent: April 10, 2018Assignee: Novadaq Technologies ULCInventors: Peter Dvorsky, David Mark Henri Goyette, T. Bruce Ferguson, Jr., Cheng Chen
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Publication number: 20180067327Abstract: An optical imaging system and related methods are provided that acquire images of an object at a distance in different spectral regions using only one camera. The systems and methods are adaptable to applications where information (simultaneous or sequential) from more than one spectral region is of interest while only one camera is available or entailed.Type: ApplicationFiled: March 22, 2016Publication date: March 8, 2018Inventors: Zhiyong Peng, T. Bruce Ferguson, JR., Cheng Chen, Kenneth Michael Jacobs
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Publication number: 20180020932Abstract: Multispectral imaging systems are provided including a first light source having a first wavelength configured to image a sample; a second light source, different from the first light source, having a second wavelength, different from the first wavelength, configured to image the sample; and at least a third light source, different from the first and second light sources, having a third wavelength, different from the first and second wavelengths, configured to image the sample. A camera is configured to receive information related to the first, second and at least third light sources from the sample. A processor is configured to combine the information related to the first, second and at least third light sources provided by the camera to image an anatomical structure of the sample, image physiology of blood flow and perfusion of the sample and/or synthesize the anatomical structure and the physiology of blood flow and perfusion of the sample in terms of a blood flow rate distribution.Type: ApplicationFiled: August 28, 2017Publication date: January 25, 2018Inventors: Cheng Chen, T. Bruce Ferguson, JR., Kenneth Michael Jacobs
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Publication number: 20180020933Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: ApplicationFiled: March 31, 2017Publication date: January 25, 2018Applicant: Novadaq Technologies Inc.Inventors: Peter DVORSKY, David Mark Henri GOYETTE, T. Bruce FERGUSON, JR., Cheng CHEN
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Patent number: 9610021Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.Type: GrantFiled: January 16, 2015Date of Patent: April 4, 2017Assignee: Novadaq Technologies Inc.Inventors: Peter Dvorsky, David Mark Henri Goyette, T. Bruce Ferguson, Jr., Cheng Chen