Abstract: The present invention relates to a novel process for isolation and recovery of compounds such as biosynthetically produced simvastatin in either lactone form or in the form of its acid salt in high yield and purity, from microbial fermentation broth and isolating the said statin from harvested microbial broth.

Abstract: A flash EPROM device (100) is disclosed. During a programming operation, a primary programming voltage circuit (116) drives I/O lines (110) to a programming voltage (Vp) according to input data values. Secondary programming voltage circuits (118) are located remotely from the primary programming voltage circuit (116) and further drive I/O lines to Vp in response to the voltage levels on the I/O lines. This arrangement reduces the effect on the load line response of the impedance intermediate the primary programming voltage circuit (116) and the secondary programming voltage circuits (118).

Abstract: A method for erasing blocks of a non-volatile memory includes detecting whether a block is in at least one of an erased state or a state secured from erasure; then setting a flag register at a first level for each block detected to be in at least one of an erased state or a state secured from erasure or at a second level for each block not so detected; then selecting for erasure blocks that have their respective flags set at the second level; and then erasing the selected blocks.

Abstract: The power-on-reset test circuit of this invention includes two imbalanced latches to detect the occurrence of a transient power-on-reset signal. The occurrence of a transient power-on-reset signal is latched for later verification during circuit testing. Both latches are designed to default to a low voltage output (Vss) on initial power-up. One of the latches is set by the power-on-reset signal to a high-voltage output (Vcc) state. The other latch is set by a reference-potential input to a low-voltage output state. If the set latch has a high-voltage output and the other latch has a low-voltage output, then the power-on-reset circuitry is functioning properly.

Abstract: An array source signal discharge controller device (10) includes a pulse converter circuit (12) that receives an erase pulse signal (ERPULSE). The pulse converter circuit (12) converts the erase pulse signal (ERPULSE) into a pulse control signal (ERPCL) that is subsequently translated into a higher voltage level bias signal (ECL.sub.--). The higher voltage level bias signal (ECL.sub.--) drives array source signal generator circuits (16) that produce array source signals (AS) to erase particular array subsections of memory as determined by a selection circuit (17). The array source signal generator circuits (16) also generate array source command signals (ASCOM.sub.--) to indicate a discharging status of all array source signals (AS). An erase completion detector circuit (18) monitors the array source command signals (ASCOM.sub.--) and generates an array source detect signal (ASDET) to indicate completion of array source signal (AS) discharging.

Abstract: The CMOS high-voltage sensor circuit has a voltage reference including, for example, of four N-channel MOS transistors; one pass-gate P-channel transistor; one current-mirror P-channel MOS transistor; and a conventional high-voltage sensor including, for example, of two P-channel MOS transistors and one N-channel MOS transistor. The sensor circuit of this invention generates a high-voltage signal at the output if the input voltage is greater than both the reference voltage plus two P-channel threshold voltages and the supply voltage Vcc plus two P-channel threshold voltages. The power-up or power-down sequence may be in any order without adversely affecting the operation of the circuit of this invention.

Abstract: The power-on reset circuit of this invention includes a current-sensing circuit, a pulse-stretching circuit, and a voltage-reference circuit. The voltage-reference circuit consists, for example, of one N-Channel and one P-Channel MOS transistor. The circuit of this invention uses a static voltage reference comprised of CMOS transistors to detect the power-up condition. The circuit of this invention improves detection of a transient power-supply voltage Vcc loss and detects that power-supply voltage transient on both rising and falling edges.

Abstract: The column-line short detection circuit of this invention includes a special test circuit that turns off wordlines (15), a N-channel transistor (23) for each column line (18), a decoder (19a) that uses only the least significant column address (20d) for input to the test circuit, and a sensor (SA) to detect current between shorted column lines (18). Because the column-line short detection circuit of this invention uses only the least significant address as input for column decoder (19a), it requires a very small number of transistors.