Patents by Inventor T. Jake Liang

T. Jake Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C Virus Culture System
    Publication number: 20110124086
    Abstract: This disclosure provides compositions and methods for producing infectious hepatitis C virus (HCV). The produced HCV can be infectious in vivo and in vitro. In one aspect, the disclosure provides an immortalized primary hepatocyte transformed with a DNA construct comprising a cDNA sequence of HCV.
    Type: Application
    Filed: September 30, 2010
    Publication date: May 26, 2011
    Inventors: Jinah Choi, T. Jake Liang
  • Synthesis and purification of hepatitis C virus-like particles
    Patent number: 6387662
    Abstract: Production of enveloped RNA virus-like particles intracellularly in vitro in insect cells using a recombinant baculovirus vector containing a cDNA coding for viral structural proteins is disclosed. In vitro production and purification of hepatitis C virus (HCV)-like particles containing HCV core protein, E1 protein and E2 protein is disclosed. Production of antibodies in vivo to the purified HCV-like particles is disclosed.
    Type: Grant
    Filed: April 21, 1999
    Date of Patent: May 14, 2002
    Assignee: The United States of America as represented by the Department of Health & Human Services
    Inventors: T. Jake Liang, Thomas F. Baumert