Abstract: Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

Abstract: A machine includes a display component that is configured to receive, from a controller of the machine, braking capacity information associated with one or more braking systems of the machine and braking utilization information associated with the one or more braking systems of the machine. The display component is configured to display, based on the braking capacity information, one or more current braking capacities of the one or more braking systems and a total current braking capacity of the one or more braking systems of the machine. The display component is configured to display, based on the braking utilization information, a current braking utilization of the machine. The controller is configured to determine the braking capacity information based on machine data associated with operation of the machine, and to determine the braking utilization information based on the machine data and worksite information associated with a worksite of the machine.

Abstract: An electric vehicle includes a battery and an external charging port on the vehicle. A charging interlock system on the vehicle includes a charging interlock module configured to: when engaged by an operator of the vehicle, prevent movement of the vehicle during a battery charging procedure executable by a battery charging technician outside the vehicle and, when disengaged by the battery charging technician following the battery charging procedure, allow movement of the vehicle.

Abstract: An axial threshing/separating system having at least one spring tined accelerator cylinder, in where the accelerator cylinder includes a plurality of double torsional spring tine cylinder elements extending from the spring tined accelerator cylinder; and one or more spring tined axial rotors, in where each of the spring tined axial rotors includes a plurality of double torsional spring tine rotor elements extending from each of the spring tined axial rotors, in where each of the spring tined axial rotors is aligned such that a respective longitudinal axis of each spring tined axial rotor is substantially coplanar and substantially parallel to a respective longitudinal axis of each other spring tined axial rotor, and wherein a longitudinal axis of at least one spring tined accelerator cylinder is substantially perpendicular to the longitudinal axis of each spring tined axial rotor.

Abstract: A method for hot-filling a polymeric container with heated product. The method includes mechanically inverting a base of the polymeric container prior to the heated product cooling in order to create a positive pressure within the container prior to cooling, and a vacuum in the container after cooling.

Abstract: A polymeric container including a finish defining an opening. A base is configured to support the container upright. A grip area is between the opening and the base. A plurality of grip panels are at the grip area. Each one of the grip panels has a depth, a height, and a width. The depth is at least 17% of the height, and the depth is at least 10% of the width.

Abstract: A polymeric container including a finish defining an opening of the container, a base, and a body. The body is between the finish and the base. The body includes a flexible panel extending entirely around the container A longitudinal axis of the container extends through an axial center of the finish, the base, the body, and the flexible panel. The flexible panel includes alternating concave portions and vertically extending columns arranged about the flexible panel. In response to a vacuum within the container resulting from filling and capping the container, the concave portions are configured to flex inward towards the longitudinal axis to become more concave, and the vertically extending columns are configured to flex outward away from the longitudinal axis of the container.

Abstract: An apparatus for controlling braking systems comprises an energy storage device to absorb energy emitted by a primary braking system. The apparatus can include a controller coupled to the energy storage device to detect conditions of the energy storage device. The controller can predict a point at which the energy storage device will exhibit reduced capability to absorb energy. The controller can provide a control signal to control a secondary braking system to provide braking capability in advance of the predicted point.

Abstract: Typically, electric power sources, such as batteries and fuel cells, require cooling to temperatures near or below ambient temperature for safe and efficient operation. Traditional cooling systems are not be able or practical to cool the components to the required temperatures, due to the lack of temperature differential between the required cooling temperature and the ambient temperature, which drives the heat transfer. Disclosed embodiments optimize the efficiency of a cooling system based on ambient conditions. In particular, embodiments determine input parameters from one or more sensed parameters, such as ambient temperature and ambient pressure, and utilize these input parameters in a process that maximizes the operation of cooling units in the most efficient mode.

Abstract: Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

Abstract: A polymeric container including a finish defining an opening. A base is configured to support the container upright. A grip area is between the opening and the base. A plurality of grip panels are at the grip area. Each one of the grip panels has a depth, a height, and a width. The depth is at least 17% of the height, and the depth is at least 10% of the width.

Abstract: A base assembly configured to cooperate with an injection blow molding machine for forming a polymeric container from a preform by injection blow molding. The base assembly includes a base insert defining a base mold configured to form a base of the polymeric container during injection blow molding. The base insert is slidably seated within the base assembly. The base insert is slidably movable between a retracted position and an extended position during injection blow molding of the polymeric container.

Abstract: A system optimizes data transmission along network paths includes a communications interface; a processor, and a non-transient computer-readable storage medium having machine instructions for path optimizing and sequencing data transmission. The processor is configured to receive a model of a utility of data transmission in the network, receive a job that includes a sequence of data transmission tasks that optimize the utility of the data transmission; determine that a sequencing process represents an intractable problem; identify a best task insertion order for inserting tasks into a sequence, retaining as a current best task insertion order, a task insertion order that produces a current best score of a general utility function, until a stopping condition is reached; and using the current best task insertion order, apply the tasks to optimize the sequence of tasks of the job.

Abstract: Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

Abstract: Systems and methods are disclosed for managing task assignments for a fleet of haul trucks at a mine site. An assignment engine may: receive state data for a haul truck including haul weight data and second state data for the mine site that is indicative of a plurality of available tasks and associated task material weight data; assign a task to the haul truck by inputting the state data into a trained reinforcement-learning model, wherein: the model has been trained to learn an assignment policy that optimizes a reward function, such that the learned policy accounts for vehicle performance variance due to changing vehicle haul weight and/or road conditions; and cause the at least one haul truck to be operated according to the at least one task assignment.

Abstract: A multi-serve polymeric container having a finish defining an opening of the container, a body, and a base. The body and the base have a substantially oval shape in cross-section, which enables the use of smaller finishes and provides for lighter weight containers.

Abstract: Systems and methods are disclosed for managing task assignments for a plurality of work machines at a site. An assignment engine may: receive first state data for a work machine including historical data, operating condition, and location data, and second state data for the site including characteristic data for materials and a plurality of available tasks; predict performance data and energy consumption data of the work machine for a task; select a task for the work machine by inputting first state data and second state data into a trained reinforcement-learning model, wherein: the model has been trained to learn an assignment policy that optimizes a reward function such that the learned policy selects a task for at least one work machine from the plurality of tasks available at the site; and cause the at least one work machine to be operated according to the at least one task assignment.

Abstract: Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

Abstract: A machine includes a display component that is configured to receive, from a controller of the machine, braking capacity information associated with one or more braking systems of the machine and braking utilization information associated with the one or more braking systems of the machine. The display component is configured to display, based on the braking capacity information, one or more current braking capacities of the one or more braking systems and a total current braking capacity of the one or more braking systems of the machine. The display component is configured to display, based on the braking utilization information, a current braking utilization of the machine. The controller is configured to determine the braking capacity information based on machine data associated with operation of the machine, and to determine the braking utilization information based on the machine data and worksite information associated with a worksite of the machine.