Patents by Inventor T.N. Thompson

T.N. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and method for developing freeze drying protocols using small batches of product
    Patent number: 11885564
    Abstract: A method and apparatus for eliminating or minimizing the non-uniformity of edge vials compared to center vials during freezing or primary drying of product therein in a freeze dryer. A temperature controlled surface is positioned in close proximity to or in contact with the edge vials to control the temperature thereof. The method and apparatus may be used to simulate in a development freeze dryer the conditions of the center and edge vials in a larger batch target freeze dryer.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: January 30, 2024
    Assignee: MILLROCK TECHNOLOGY, INC.
    Inventors: T. N. Thompson, Qiming Wang, Richard Martino
  • Apparatus and method for developing freeze drying protocols using small batches of product
    Patent number: 11486640
    Abstract: A method of monitoring and controlling a freeze drying process in a freeze drying apparatus having walls, shelves and a number of vials or trays positioned on different areas of the shelves and containing product to be freeze dried. One or more vials or trays are selected that are representative of the positions of all of the vials or trays in different areas of the shelves. One or more heat flux sensors are positioned between the selected vials or trays and adjacent portions of the walls and/or shelves. The heat transfer between the selected vials or trays and the adjacent wall or shelf portions is measured during the freezing and drying stages of the freeze drying process.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: November 1, 2022
    Assignee: MILLROCK TECHNOLOGY, INC.
    Inventors: T. N. Thompson, Qiming Wang, Richard Martino, Weijia Ling
  • APPARATUS AND METHOD FOR DEVELOPING FREEZE DRYING PROTOCOLS USING SMALL BATCHES OF PRODUCT
    Publication number: 20200149815
    Abstract: A method and apparatus for eliminating or minimizing the non-uniformity of edge vials compared to center vials during freezing or primary drying of product therein in a freeze dryer. A temperature controlled surface is positioned in close proximity to or in contact with the edge vials to control the temperature thereof. The method and apparatus may be used to simulate in a development freeze dryer the conditions of the center and edge vials in a larger batch target freeze dryer.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 14, 2020
    Inventors: T.N. THOMPSON, Qiming WANG, Richard MARTINO
  • Apparatus and method for developing freeze drying protocols using small batches of product
    Patent number: 10605527
    Abstract: A method and apparatus for eliminating or minimizing the non-uniformity of edge vials compared to center vials during freezing or primary drying of product therein in a freeze dryer. A temperature controlled surface is positioned in close proximity to or in contact with the edge vials to control the temperature thereof. The method and apparatus may be used to simulate in a development freeze dryer the conditions of the center and edge vials in a larger batch target freeze dryer.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: March 31, 2020
    Assignee: MILLROCK TECHNOLOGY, INC.
    Inventors: T. N. Thompson, Qiming Wang, Richard A. Martino
  • APPARATUS AND METHOD FOR DEVELOPING FREEZE DRYING PROTOCOLS USING SMALL BATCHES OF PRODUCT
    Publication number: 20190285342
    Abstract: A method of monitoring and controlling a freeze drying process in a freeze drying apparatus having walls, shelves and a number of vials or trays positioned on different areas of the shelves and containing product to be freeze dried. One or more vials or trays are selected that are representative of the positions of all of the vials or trays in different areas of the shelves. One or more heat flux sensors are positioned between the selected vials or trays and adjacent portions of the walls and/or shelves. The heat transfer between the selected vials or trays and the adjacent wall or shelf portions is measured during the freezing and drying stages of the freeze drying process.
    Type: Application
    Filed: May 1, 2019
    Publication date: September 19, 2019
    Inventors: T.N. THOMPSON, Qiming WANG, Richard MARTINO, Weijia LING
  • APPARATUS AND METHOD FOR DEVELOPING FREEZE DRYING PROTOCOLS USING SMALL BATCHES OF PRODUCT
    Publication number: 20170082361
    Abstract: A method and apparatus for eliminating or minimizing the non-uniformity of edge vials compared to center vials during freezing or primary drying of product therein in a freeze dryer. A temperature controlled surface is positioned in close proximity to or in contact with the edge vials to control the temperature thereof. The method and apparatus may be used to simulate in a development freeze dryer the conditions of the center and edge vials in a larger batch target freeze dryer.
    Type: Application
    Filed: August 4, 2016
    Publication date: March 23, 2017
    Applicant: Millrock Technology, Inc.
    Inventors: T.N. Thompson, Qiming Wang, Richard A. Martino