Abstract: A liquid handling device having an upstream liquid handling structure connected to a downstream liquid handling structure by a conduit. The upstream and downstream liquid handling structures are sealed or sealable such that the conduit provides the only fluidic communication paths between the upstream and downstream liquid handling structure. The device is arranged such that a driving force causes liquid in the upstream liquid handling structure to at least partially fill the conduit to separate gas in the upstream liquid handling structure from gas in the downstream liquid handling structure. With the device set up such that the two gas volumes are separated by a liquid volume, gas pressures and liquid flow in the device can be controlled by control of the driving force. The device may be arranged for rotation about an axis of rotation to provide the driving force.

Abstract: Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved.

Abstract: Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: A liquid handling device having an upstream liquid handling structure connected to a downstream liquid handling structure by a conduit. The upstream and downstream liquid handling structures are sealed or sealable such that the conduit provides the only fluidic communication paths between the upstream and downstream liquid handling structure. The device is arranged such that a driving force causes liquid in the upstream liquid handling structure to at least partially fill the conduit to separate gas in the upstream liquid handling structure from gas in the downstream liquid handling structure. With the device set up such that the two gas volumes are separated by a liquid volume, gas pressures and liquid flow in the device can be controlled by control of the driving force. The device may be arranged for rotation about an axis of rotation to provide the driving force.

Abstract: Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved.