Abstract: The hyaluronidase, which is a hyaluronic acid-specific endo-.beta.-glucuronidase, having a molecular weight of about 28,500 in non-reduced form, is derived from buffalo leeches (that is, leeches of the sub-family Hirudinariinae, such as the species Hirudinaria manillensis or Poecilobdella granulosa).The hyaluronidase, which cleaves hyaluronic acid, but not chondroitin, chondroitin -4- sulphate, chondroitin -6- sulphate or heparin, is considerably more stable at high temperatures and extremes of pH than known leech hyaluronidase. It has a wide range of uses where breakdown of hyaluronic acid is required; of particular interest is in pharmaceutical or veterinary formulations, either as an active agent or a spreading or percutaneous factor. The hyaluronidase is useful for stimulating flow of physiological fluids in the eye (for example, in the treatment of glaucoma).

Abstract: This invention provides a Gatling type gun having a housing; a rotor journaled for rotation with respect to said housing; said rotor having a plurality of gun bolts disposed in an annular row with respective firing pin assemblies which do not include a firing pin spring; switchable firing pin assembly control means mounted to said housing for sequentially engaging each of said firing pin assemblies during rotation of said rotor and having a first disposition for positively projecting the forward tip of each firing pin forward of the face of its respective gun bolt by coupling the kinetic energy of the rotor to the firing pin over a period of time, and a second disposition for positively precluding the forward tip of each firing pin from projecting forward of the face of its respective gun bolt, and switching means coupled to said control means for remotely switching said control means to and between said first and second dispositions.

Abstract: Halogenated carbon compounds containing at least three halogen atoms and capable of undergoing bimolecular nucleophilic substitution are degraded by reaction in an aprotic solvent with a strong nucleophile selected from superoxide ion and hydroxide ion. The process is particularly applicable to compounds in which at least three halogen atoms are covalently joined to a tetrahedral carbon atom. In a specific embodiment, superoxide ion is electrolytically generated in an aprotic solvent containing a soluble organic electrolyte. In a further embodiment, the aprotic solvent is dimethyl sulfoxide, which, when converting carbon tetrahalide, forms dimethylsulfone and carbonate.

Abstract: Novel fibrinolytic factors obtained from the salivary glands of Haementeria ghilianii. Proteins having molecular weights under about 100,000 are isolated from the salivary glands of H. ghilianii. The proteins show cathodic mobility in electrophoresis and uninhibited peptidase activity with fibrinogen in plasma.

Abstract: A method for enhancing chemical reactions in a constantly flowing stream of liquid character fortified with oxidizing agents, such as air or oxygen or other chemical agents, makes use of an inner resonant tube concentrically mounted within an outer resonant tube with the walls of the tubes spaced from each other forming an annular passageway for the flow of liquid from one end of the passageway to the other. One or more sets of radially spaced ultrasonic transducers are located on the outside wall of the outer resonant tube thereby to create an ultrasonic cavitation condition in the liquid as it flows through the annular passageway.

Abstract: A feature of this invention is the provision of a Gatling type gun having a firing/safing cam assembly having three dispositions: one permitting firing in one direction of rotation; another permitting firing in the other direction of rotation; and yet another precluding firing in either direction of rotation of the rotor, all by means of two independently operated cam elements and a continuum element operated as a function of the respective dispositions of said cam elements.

Abstract: An apparatus for enhancing chemical reactions in a constantly flowing stream of liquid character fortified with oxidizing agents, such as air or oxygen or other chemical agents, makes use of an inner resonant tube concentrically mounted within an outer resonant tube with the walls of the tubes spaced from each other forming an annular passageway for the flow of liquid from one end of the passageway to the other. One or more sets of radially spaced ultrasonic transducers are located on the outside wall of the outer resonant tube thereby to create an ultrasonic cavitation condition in the liquid as it flows through the annular passageway.

Abstract: A continuous self-cleaning filter for liquids has an outer resonant tube concentrically mounted around an inner composite tube in spaced relationship providing an annular chamber between them. There is an inflow at one end of the annular chamber for the liquid and an outflow at the other end for residual concentrate. The inner composite tube has an outlet at one end for clear effluent and a closed opposite end. A relatively thin walled perforate liner enveloped in a filter blanket comprises the composite tube.

Abstract: In a substantially conventional system for receiving and conveying a fluid suspension of material there is an endless porous belt screen on which the material is spread and a tray beneath the belt to catch liquid which passes through the belt. A suction box beneath the belt near the area of deposition draws off some liquid. Superimposed on the conventional system is a resonant frequency energy source in the form of a roll assembly consisting in part of an outer shell in the form of an exterior cylindrical roll supported on shock mounts and in constant engagement with the underside of the belt. The exterior cylindrical roll is driven at a circumferential speed equal to the linear speed of travel of the belt.

Abstract: For the continuous mixing of fluid process materials or gases as they flow uninterrupted from a point of initial mixing to a discharge end and processed by means of intense vaporous cavitation, use is made of a resonant tube section having an entrance end and an exit end. The tube section is isolated from the rest of the supporting structure by means of resilient isolation mounts. A source of sinusoidal energy is connected to and excites the resonant tube section into one of its modes of natural frequency causing intense resonant sinusoidal acoustic energy to be developed and transmitted in spherical fashion from the inner resonant tube wall and throughout the flowing fluids. The energy thus released generates intense acoustical vaporous cavitation energy which breaks the surface tension and mixes the materials.