Abstract: A compound of formula (I): in which R1-R8, A, B, X, Y, m, and n are as defined herein. Also disclosed is a method for detecting a cancer cell using a compound of formula I.

Abstract: This invention relates to a pharmaceutical composition for treating cancer, comprising an effective amount of a compound represented by formula (I): wherein R is —CCOCCOCC— or —CCOCCOCCOCC—; and a pharmaceutical acceptable carrier. This invention also relates to a method for treating cancer, comprising administering a therapeutically effective amount of said compound to a subject; and a method for stabilizing G4 structure of telomere by using this compound.

Abstract: A compound of formula (I): in which R1-R8, A, B, X, Y, m, and n are as defined herein. Also disclosed is a method for detecting a cancer cell using a compound of formula I.

Abstract: This invention relates to a device for detecting cancer cells. The device includes a light source for generating light (e.g., a light emitting diode), a first optical filter selected from the group consisting of a band pass filter and a long pass filter, a second optical filter (i.e., a band pass filter) disposed between the light source and the first optical filter, and a sample receiver for receiving a sample. The sample receiver is disposed between the first and second optical filters. The first optical filter, the sample receiver, and the second optical filter are aligned so that light emitted from the light source passes sequentially through the second optical filter, the sample receiver, and the first optical filter.

Abstract: This invention relates to a device for detecting cancer cells. The device includes a light source for generating light (e.g., a light emitting diode), a first optical filter selected from the group consisting of a band pass filter and a long pass filter, a second optical filter (i.e., a band pass filter) disposed between the light source and the first optical filter, and a sample receiver for receiving a sample. The sample receiver is disposed between the first and second optical filters. The first optical filter, the sample receiver, and the second optical filter are aligned so that light emitted from the light source passes sequentially through the second optical filter, the sample receiver, and the first optical filter.

Abstract: This invention relates to carbazole compounds of the following formula: In the above formula, each of rings A and B, independently, is heteroaryl containing at least one nitrogen atom; each of X and Y, independently, is CH or N; each of R1–R6, independently, is H, C1–C8 alkyl, C2–C8 alkenyl, C2–C8 alkynyl, C3–C8 cycloalkyl, C3–C8 heterocycloalkyl, aryl, heteroaryl, OH, C1–C6 alkoxy, aryloxy, heteroaryloxy, NH2, C1–C6 alkylamino, C1–C12 dialkylamino, arylamino, diarylamino, or halogen; R7 is H, C1–C8 alkyl, C2–C8 alkenyl, C2–C8 alkynyl, C3–C8 cycloalkyl, C3–C8 heterocycloalkyl, aryl, heteroaryl; and <each of m and n, independently, is 1, 2, or 3.

Abstract: This invention relates to a method for detecting cancer cells in a subject. The method includes contacting a plurality of cells in a sample obtained from the subject with carbazole compounds of the following formula: and calculating the percentage of the cells that emit florescence upon irradiation with an excitation light, in which, if the percentage is above a pre-set value, the subject is determined to contain cancer cells. In the above formula, each of rings A and B, independently, is heteroaryl containing at least one nitrogen atom; each of X and Y, independently, is CH or N; each of R1—R6, independently, is H, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, heteroaryl, OH, C1-C6 alkoxy, aryloxy, heteroaryloxy, NH2, C1l-C6 alkylamino, C1-C12 dialkylamino, arylamino, diarylamino, or halogen; R7 is H, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, heteroaryl; and each of m and n, independently, is 1, 2, or 3.

Abstract: This invention relates to carbazole compounds of the following formula: In the above formula, each of rings A and B, independently, is heteroaryl containing at least one nitrogen atom; each of X and Y, independently, is CH or N; each of R1-R6, independently, is H, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, heteroaryl, OH, C1-C6 alkoxy, aryloxy, heteroaryloxy, NH2, C1-C6 alkylamino, C1-C12 dialkylamino, arylamino, diarylamino, or halogen; R7 is H, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, heteroaryl; and each of m and n, independently, is 1, 2, or 3.