Abstract: Systems and methods for the dispensing of liquid, and automated layering of liquid hydrogel patterns are disclosed. In some embodiments, the systems and methods described herein may utilize a bioprinter having a brush that is configured to pattern a collagen layer. In some embodiments, the bioprinter may be used to make layered bioprinted materials. In some embodiments, the systems and methods described herein may include a bioprinter having an atomizer needle that is configured to dispense liquid in an automated way. In some embodiments, the disclosed systems and methods may provide modified surfaces upon which materials may be printed using a three-dimensional (3D) bioprinter. In one embodiment, a modified surface may be formed of polydimethylsiloxane (PDMS), silicones and the like.

Abstract: Disclosed are systems and methods for a bioprinter capable of printing an object having biological components. In some embodiments, the bioprinter includes a modular print bed having a recessed area configured to receive a variable insert and a printer head positioned above the modular print bed. In some embodiments, the printer head has a cartridge for receiving and holding a biomaterial, and an extruder configured to extrude biomaterials from the cartridge onto a portion of the variable insert. The variable insert may include functional elements (e.g., heating, cooling, photocuring) and/or receiving elements (e.g., well plates).

Abstract: Systems and methods for the dispensing of liquid, and automated layering of liquid hydrogel patterns are disclosed. In some embodiments, the systems and methods described herein may utilize a bioprinter having a brush that is configured to pattern a collagen layer. In some embodiments, the bioprinter may be used to make layered bioprinted materials. In some embodiments, the systems and methods described herein may include a bioprinter having an atomizer needle that is configured to dispense liquid in an automated way. In some embodiments, the disclosed systems and methods may provide modified surfaces upon which materials may be printed using a three-dimensional (3D) bioprinter. In one embodiment, a modified surface may be formed of polydimethylsiloxane (PDMS), silicones and the like.