Abstract: Crystals of the compound represented by formula (1), a method for the production thereof, and a method for producing an antibody-drug conjugate using the crystals.

Abstract: The present invention makes a variety of improvements on the conventional television receiver to enhance the home communication capability thereof, thereby making the television receiver available as an information terminal apparatus for household use. The novel television receiver that receives a television signal to display a television image on screen comprising: a memory; a microphone through which voice information is entered externally; writing section for writing at least one piece of the voice information entered through the microphone and additional information associated with the at least one piece of voice information into the memory; and a display device for reproducing the at least one piece of voice information stored in the memory and outputting the reproduced voice information through a speaker and displaying the additional information associated with the at least one piece of voice information onto the screen.

Abstract: An optical disc is disclosed in which a pair of circular disc substrates are arranged in confronted relation with each other with their signal recording layers being directed inwardly and are bonded to each other through spacers at inner and outer peripheral portions. A vent hole is formed in a main surface of one of the disc substrates. A disc label is bonded on the disc substrate so as to cover the vent hole.

Abstract: A circuit for detecting a proper locked state between the output of a phase-locked loop clock generating circuit and a timing component of a received composite signal containing both digital information and the timing component. An internal synchronization pulse signal is produced directly in response to the output of the phase-locked loop, and a frame synchronization sequence detection pulse signal is produced by detecting the occurrence of frame synchronization sequences in the composite signal. The internal synchronization pulse signal and the frame synchronization sequence detection pulse signal are compared to determine whether or not they are in time coincidence. If they are not, corresponding to an improperly locked state, a synchronization hunting controller controls the internal synchronization pulse generator to shift the phase of the internal synchronization pulse signal until time coincidence occurs. The output of the synchronization hunting controller is also used a lock detection signal.