Patents by Inventor Tadakazu Takakura

Tadakazu Takakura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF
    Publication number: 20090118169
    Abstract: A compound comprising the atom corresponding to N3 and the two or more atoms selected from N1, N2, N4 and N5, said atoms constitute the pharmacophore represented by the following formula: wherein N1 represents an atom to which a donative hydrogen atom in a hydrogen-bond donating group is bonded or a hydrogen-bond accepting atom in a hydrogen-bond accepting group; N3 represents a hydrogen-bond accepting atom in a hydrogen-bond accepting group; and N2, N4 and N5 independently represents an arbitrary carbon atom constituting a hydrophobic group and defined by the interatomic distances between N1, N2, N3, N4 and N5; and, in the optimized three-dimensional structure thereof, the distances between the atom corresponding to N3 and the two or more atoms selected from N1, N2, N4 and N5, in the optimized steric structure thereof, are the interatomic distances in a pharmacophore; or a salt thereof; inhibits the activity of transcription factor AP-1 and is useful as an agent for preventing and treating the diseases i
    Type: Application
    Filed: November 16, 2007
    Publication date: May 7, 2009
    Applicant: TOYAMA CHEMICAL CO., LTD.
    Inventors: Hisaaki Chaki, Tadakazu Takakura, Keiichi Tsuchida, Hironori Kotsubo, Yukihiko Aikawa, Shuichi Hirono, Shunichi Shiozawa
  • Compounds and medicinal use thereof
    Patent number: 7314888
    Abstract: A compound or a salt thereof having the atom corresponding to N3 and the two or more atoms selected from N1, N2, N4 and N5, said atoms constitute the pharmacophore represented by the following formula: and inhibits the activity of transcription factor AP-1 and is useful as an agent for preventing and treating the diseases into which over expression of AP-1 participates and as an AP-1 inhibitor.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: January 1, 2008
    Assignee: Toyama Chemical Co., Ltd.
    Inventors: Hisaaki Chaki, Tadakazu Takakura, Keiichi Tsuchida, Hironori Kotsubo, Yukihiko Aikawa, Shuichi Hirono, Shunichi Shiozawa
  • 1,2-benzoisoxazole derivative or its salt and brain-protecting agent comprising the same
    Patent number: 5578627
    Abstract: This invention relates to a 1,2-benzoisoxazole derivative represented by the following general formula (I) or its salt: ##STR1##
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: November 26, 1996
    Assignee: Toyama Chemical Co., Ltd.
    Inventors: Kenji Takeda, Nobuo Terashima, Joji Nakano, Hisashi Minami, Toyokazu Kobayashi, Kunikazu Furuhata, Tadakazu Takakura, Makoto Takata, Hiroyo Kawafuchi, Toru Hiraiwa