Patents by Inventor Tadanori Tomita

Tadanori Tomita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition for treating cancer
    Patent number: 11389497
    Abstract: Presently claimed invention related to a pharmaceutical composition comprising ascorbic acid caffeoylquinic acid, rosmarinic acid. and glycosyl sulfones obtained from Ocimum Sanctum and a process for isolating said composition from Ocimum Sanctum. Presently claimed invention also provides a method of treating neural crest derived tumors such as malignant neurofibroma and melanoma.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: July 19, 2022
    Assignee: Prime Bio, Inc.
    Inventors: Bal Ram Singh, Chandra K Mayanil, Tadanori Tomita, Raj Kumar
  • Inhibitors of polo-like kinase 4 (PLK4) for treating pediatric embryonal tumors
    Patent number: 11197863
    Abstract: Disclosed are methods and compositions for treating pediatric embryonal tumors. The methods and compositions utilize or include an inhibitor of polo-like kinase 4 (PLK4) for treating pediatric embryonal tumors.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: December 14, 2021
    Assignee: ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO
    Inventors: Simone T. Sredni, Tadanori Tomita
  • INHIBITORS OF POLO-LIKE KINASE 4 (PLK4) FOR TREATING PEDIATRIC EMBRYONAL TUMORS
    Publication number: 20190070190
    Abstract: Disclosed are methods and compositions for treating pediatric embryonal tumors. The methods and compositions utilize or include an inhibitor of polo-like kinase 4 (PLK4) for treating pediatric embryonal tumors.
    Type: Application
    Filed: August 29, 2018
    Publication date: March 7, 2019
    Applicant: Northwestern University
    Inventors: Simone T. Sredni, Tadanori Tomita
  • Magnetic nanostructures as theranostic agents
    Patent number: 9095629
    Abstract: The present invention relates to magnetic nanostructures as theranostic agents, which provide dual function as diagnostic and therapeutic agents. In particular, the present invention relates to compositions comprising magnetic nanostructures and their use as targeted therapeutic agents for cancers (e.g., medulloblastoma) and Alzheimer's disease and related diseases and conditions.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: August 4, 2015
    Assignees: NORTHWESTERN UNIVERSITY, ANN & ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO
    Inventors: Vinayak P. Dravid, Saurabh Sharma, Tadanori Tomita, Kirsten L. Viola, William L. Klein
  • Compositions and Methods of Detecting and Treating Neural Tube Defects
    Publication number: 20150025008
    Abstract: The present invention generally relates to compositions, reagents and methods for detecting and treating a neural tube defect in a fetus. One aspect of the invention provides a method including administrating a composition containing noggin or LDN-193189 to the fetus in utero. In certain embodiments, the composition is administrated if the maternal blood or amniotic fluid contains an elevated amount of BMP4 and/or a reduced amount of noggin. In another aspect of the invention, the method includes administrating a composition containing GDC-0449 to the fetus in utero. In certain embodiments, the GDC-0449 is administrated if the maternal blood or amniotic fluid contains an elevated amount of sonic hedgehog.
    Type: Application
    Filed: July 15, 2014
    Publication date: January 22, 2015
    Inventors: Chandra Shekhar Mayanil, Elise Allender, Takao Tsurubuchi, Norman Ginsberg, David G. McLone, Tadanori Tomita
  • Method of Detecting and Profiling Progression of the Risk of Neurodegenerative Diseases
    Publication number: 20130029998
    Abstract: The present invention generally relates to methods of detecting and profiling progression of the risk of neurodegenerative diseases in a subject. In one embodiment, the method includes isolating a stem cell from cerebrospinal fluid of the subject and determining the level of H3K27 methylation within the stem cell. The subject is determined to have an increased risk of developing the neurodegenerative disease if the level of H3K27 methylation is elevated. In various embodiments, the neurodegenerative disease is Alzheimer's Disease, Parkinson's Disease or Amyotrophic Lateral Sclerosis.
    Type: Application
    Filed: April 21, 2011
    Publication date: January 31, 2013
    Inventors: Chandra Shekhar Mayanil, Shunsuke Ichi, Tadanori Tomita
  • MAGNETIC NANOSTRUCTURES AS THERANOSTIC AGENTS
    Publication number: 20120308657
    Abstract: The present invention relates to magnetic nanostructures as theranostic agents, which provide dual function as diagnostic and therapeutic agents. In particular, the present invention relates to compositions comprising magnetic nanostructures and their use as targeted therapeutic agents for cancers (e.g., medulloblastoma) and Alzheimer's disease and related diseases and conditions.
    Type: Application
    Filed: November 1, 2010
    Publication date: December 6, 2012
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Vinayak P. Dravid, Saurabh Sharma, Tadanori Tomita, Kirsten L. Viola, William L. Klein