Abstract: A mass spectrometry apparatus which includes an ion source which ionizes a sample under atmospheric pressure and outputs the ionized sample, a differential pumping region, provided with apertures, for receiving under vacuum ions in the ionized sample from the ion source and outputting the ions and an ion accelerating and focusing region, having a plurality of ion accelerating electrodes each having applied thereto a voltage, for accelerating and focusing under vacuum the ions from the differential pumping region. The ions from the accelerating and focusing region are introduced under vacuum to a mass spectrometer which detects and analyzes the ions.

Abstract: An atmospheric pressure ionization spectrometer capable for continuously detecting impurities included in air or gas can be realized. The air or gas is stored in a daily storage such as a bag, a package, a pocket or the like. An air suction probe is connected to an ion source through an insulation pipe, and the ion source is connected to an air exhaust pump through an exhaust port and an insulation pipe. The ion source has a needle electrode, a first small hole electrode, an intermediate pressure portion and a second small hole electrode, and the needle electrode is connected to a power source, and the first and second small hole electrodes are connected to an ion accelerating power source. The intermediate pressure portion is connected to a vacuum pump through the exhaust port. An electrostatic lens is disposed in the stage following the intermediate pressure portion, and a mass spectrometric portion and a detector are disposed in the stage following the electrostatic lens.

Abstract: A nebulized jet from a nebulizer is subjected to mechanical agitation and stirring to render the mists uniform and fine, then the droplets of the mists thus rendered uniform and fine are ionized. By accelerative collision of the resulting ions in a medium pressure chamber it is made possible to effect desolvation efficiently. Consequently, chemical noises caused by cluster ions can be greatly diminished and it is possible to attain high sensitive measurement of a sample in atmospheric pressure ionizations LC/MS.

Abstract: Ions generated by an ES ion supply are introduced into a mass spectrometer portion through a small hole in a second electrode after passing through a small hole in a heated first electrode, and are analyzed by a mass spectrometer. Corresponding to heating of the first electrode, a length of the small hole in the first electrode is determined to a predetermined adequate value.

Abstract: An ion beam having a good converging property and a good quality is provided by satisfying the limitations controlling both angle of dispersion and the width of beam at the same time. The voltage 12d of a repeller electrode 1f in an ion source of electron bombardment type is input to an ion source state monitor 11 and the ion source state monitor 11 output a predicted value 12e of the voltage applied to an extractor electrode 1g to an extractor power source 9. As for the extractor electrode system, the width of a slit in the acceleration electrode 1b is made larger than the width of a slit of the extractor electrode 1g, and the extractor electrode 1g is set in a position apart from the acceleration electrode 1b by the distance nearly equal to the distance between the acceleration electrode 1b and the ion generating region 2a. By doing so, the electric field leaked from the slit of the acceleration electrode 1b to the inside of the ionization chamber 1a expands to the vicinity of the ion generating region.

Abstract: A mass spectrometric apparatus is disclosed which has quadrupole electrodes to which a DC voltage and a high-frequency voltage are applied in a superposed manner, and measures a mass spectrum by scanning particular mass numbers of ions passing through respective stable regions by changing the DC voltage and the high-frequency voltage in very small steps every predetermined time interval step while keeping a relationship in magnitude between the DC voltage and the high-frequency voltage in the stable regions which provide stable trajectories of the ions of the respective mass numbers.

Abstract: Ions generated by an ES ion supply are introduced into a mass spectrometer portion through a small hole in a second electrode after passing through a small hole in a heated first electrode, and are analyzed by a mass spectrometer. Corresponding to heating of the first electrode, a length of the small hole in the first electrode is determined to a predetermined adequate value.

Abstract: A liquid chromatograph-direct coupled mass spectrometer, which comprises a liquid chromatograph section, a mass spectrometer section and an interface section coupling the liquid chromatograph section with the mass spectrometer section, the interface section being provided with a first nebulizing means for nebulizing an eluate of a hydrophobic solvent containing a sample in solution introduced from the liquid chromatograph section through a capillary continuously into a vacuum or atmospheric pressure region and the first nebulizing means being further provided with a second nebulizing means for nebulizing a hydrophilic solvent and with a heating means for heating the first and second nebulizing means has a high separability and has no limit to selection of a mobile phase solvent and an ionization solvent.

Abstract: An atmospheric pressure ionization type mass spectrometer comprises an ionization section opened to the atmosphere including a desolvation chamber, an ionization chamber, and a corona discharge needle for ionizing sample, a mass analysis section including a mass spectrometry, an intermediate pressure section in which cluster ions of the sample are accelerated by a drift voltage from the ionization section towards the mass analysis section. In advance of the mass spectroscopy, the moisture in the atmosphere is ionized into the water cluster ions. Such water cluster ions are used for calibrating a mass marker of the mass spectrometry.

Abstract: An atmospheric pressure ionization mass spectrometer has an interface by which the mass spectrometer is coupled on-line to a liquid chromatograph. This interface comprises an atomization unit which heats and atomizes a sample carried out by a mobile phase from the liquid chromatograph. The atomization unit includes a sample introducing pipe having therein a plurality of thin passages which extend along an axis of the pipe and into which the sample is introduced for atomization.