Abstract: The purpose of the present invention is to provide a pre-filled syringe formulation with staked needle, which contains an antibody at a high concentration and can be produced on an industrial scale in a simple manner without causing clogging. A pre-filled syringe formulation with staked needle, in which a protein solution is packed. The pre-filled syringe formulation is characterized in that a cap formed with a material having low water vapor permeability is provided at the needle.

Abstract: A system in an industrial plant which has a plurality of manual valves for controlling an amount of fluid flowing through pipes provided in an industrial plant of an embodiment includes: a measuring instrument sensor measuring a state of the plant so as to output a signal indicating measurement result; a transmitter wirelessly transmitting the measured signal; a receiver wirelessly receiving the transmitted signal; and a monitoring and controlling device collecting the received signal, in which the receivers are provided to the manual valves.