Patents by Inventor Tadashi Nagakura

Tadashi Nagakura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xanthine derivative and DPPIV inhibitor
    Publication number: 20040082570
    Abstract: The present invention provides novel compounds exhibiting an excellent DPPIV inhibition effect.
    Type: Application
    Filed: February 24, 2003
    Publication date: April 29, 2004
    Applicant: Eisai Co., Ltd.
    Inventors: Seiji Yoshikawa, Eita Emori, Fumiyoshi Matsuura, Richard Clark, Hironori Ikuta, Nobuyuki Yasuda, Tadashi Nagakura, Kazuto Yamazaki, Mika Aoki
  • Phthalazine compounds and therapeutic agents for erectile dysfunction
    Patent number: 6699870
    Abstract: The present invention provides a phthalazine compound as a therapeutic agent for erectile dysfunction represented by the following formula, a pharmacologically acceptable salt thereof or a hydrate thereof: wherein R1 and R2 are the same as or different from each other and represent a halogen atom, a C1 to C4 alkyl group which may be substituted with a halogen atom, a C1 to C4 alkoxy group which may be substituted with a halogen atom or a cyano group; X represents a cyano group, a nitro group, a halogen atom, a hydroxyimino group which may be substituted or a heteroaryl group which may be substituted; Y represents a heteroaryl group, an aryl group which may be substituted, an alkynyl group which may substituted, an alkenyl group, an alkyl group, an optionally substituted saturated or unsaturated 4- to 8-membered amine ring, and the cyclic amine compound is a monocyclic compound, bicyclic compound or a spiro compound; l is an integer of 1 to 3; provided that the case where l is 1 or 2, X is a
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: March 2, 2004
    Assignee: Eisai Co., Ltd.
    Inventors: Nobuhisa Watanabe, Norio Karibe, Kazuki Miyazaki, Fumihiro Ozaki, Atsushi Kamada, Shuhei Miyazawa, Yoshimitsu Naoe, Toshihiko Kaneko, Itaru Tsukada, Tadashi Nagakura, Hiroki Ishihara, Kohtarou Kodama, Hideyuki Adachi
  • Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them
    Publication number: 20030181766
    Abstract: Amidino derivatives represented by the following general formula (I): 1
    Type: Application
    Filed: November 14, 2002
    Publication date: September 25, 2003
    Inventors: Takashi Satoh, Yasushi Okamoto, Osamu Asano, Nobuhisa Watanabe, Tadashi Nagakura, Takao Saeki, Atsushi Inoue, Masahiro Sakurai
  • Phthalazine compounds and therapeutic agents for erectile dysfunction
    Publication number: 20030105074
    Abstract: The present invention provides a phthalazine compound as a therapeutic agent for erectile dysfunction represented by the following formula, a pharmacologically acceptable salt thereof or a hydrate thereof: 1
    Type: Application
    Filed: October 28, 2002
    Publication date: June 5, 2003
    Applicant: Eisai Co., Ltd.
    Inventors: Nobuhisa Watanabe, Norio Karibe, Kazuki Miyazaki, Fumihiro Ozaki, Atsushi Kamada, Shuhei Miyazawa, Yoshimitsu Naoe, Toshihiko Kaneko, Itaru Tsukada, Tadashi Nagakura, Hiroki Ishihara, Kohtarou Kodama, Hideyuki Adachi
  • Pharmaceutical use of N-carbamoylazole derivatives
    Publication number: 20030060494
    Abstract: The present invention relates to use of 1-carbamoylazole derivatives as medicaments and pharmaceutical compositions containing 1-carbamoylazole derivatives as the active ingredient, based on their DPPIV inhibiting effects.
    Type: Application
    Filed: May 15, 2002
    Publication date: March 27, 2003
    Inventors: Nobuyuki Yasuda, Tadashi Nagakura, Kazuto Yamazaki, Seiji Yoshikawa, Toshimi Okada, Hironori Ikuta, Mika Koyanagi
  • Phthalazine derivatives and remedies for erectile dysfunction
    Patent number: 6498159
    Abstract: The present invention provides a phthalazine compound as a therapeutic agent for erectile dysfunction represented by the following formula, a pharmacologically acceptable salt thereof or a hydrate thereof: wherein R1 and R2 are the same as or different from each other and represent a halogen atom, a C1 to C4 alkyl group which may be substituted with a halogen atom, a C1 to C4 alkoxy group which may be substituted with a halogen atom or a cyano group; X represents a cyano group, a nitro group, a halogen atom, a hydroxyimino group which may be substituted or a heteroaryl group which may be substituted; Y represents a heteroaryl group, an aryl group which may be substituted, an alkynyl group which may substituted, an alkenyl group, an alkyl group, an optionally substituted saturated or unsaturated 4- to 8-membered amine ring, and the cyclic amine compound is a monocyclic compound, bicyclic compound or a spiro compound; l is an integer of 1 to 3; provided that the case where l is 1 or 2, X is a
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: December 24, 2002
    Assignee: Eisai Co., Ltd.
    Inventors: Nobuhisa Watanabe, Norio Karibe, Kazuki Miyazaki, Fumihiro Ozaki, Atsushi Kamada, Shuhei Miyazawa, Yoshimitsu Naoe, Toshihiko Kaneko, Itaru Tsukada, Tadashi Nagakura, Hiroki Ishihara, Kohtarou Kodama, Hideyuki Adachi