Patents by Inventor Tadayuki Kouda

Tadayuki Kouda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5710152
    Abstract: A benzoazine derivative represented by the following formula (1), ##STR1## wherein R.sup.1 represents an alkyl group, alkoxy group, halogen atom, halogenoalkyl group, amino group, hydroxy group, benzyloxy group which may have a substituent, cyano group, carbamoyl group, acyl group, nitro group, carboxy group, or sulfonamide group; R.sup.2 and R.sup.3 may be the same or different and each individually represents a hydrogen atom or an alkyl group, or R.sup.2 and R.sup.3 indicate in combination an alkylene group having 2-7 carbon atoms; R.sup.4 and R.sup.5 may be the same or different and each individually represents a hydrogen atom or an alkyl group; X denotes O, S, or N--R.sup.6 (wherein R.sup.6 represents a hydrogen atom, an alkyl group, or an aryl group or pyridyl group which may have a substituent); m is an integer from 0 to 4; and n is an integer from 1 to 3, or a salt of the benzoazine derivative.
    Type: Grant
    Filed: January 30, 1997
    Date of Patent: January 20, 1998
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Yoshihiro Nagao, Yoshikuni Ito, Jiro Kotake, Tadayuki Kouda, Haruyoshi Honda, Susumu Sato, Hideaki Matsuda
  • Patent number: 4866176
    Abstract: A 8-piperazinyl-1,7-naphthyridine derivative represented by the following formula (I): ##STR1## in which R represents a hydrogen atom, formyl group, acyl group, aroyl group, heteroaroyl group, substituted phenyl group, pyridyl group, aralkyl group or substituted or unsubstituted benzenesulfonyl group; and an acid adduct salt thereof. The compound has excellent antiinflammatory, antiarrhythmic and cardiotonic effects, and thus is useful as an antiinflammatory drug and a medicine for circulatory organs.
    Type: Grant
    Filed: August 13, 1987
    Date of Patent: September 12, 1989
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Haruyoshi Honda, Yuko Yoshida, Tadayuki Kouda, Hideaki Matsuda, Tatsuhiko Katori
  • Patent number: 4728659
    Abstract: Disclosed herein are aminomethyl derivatives each of which is of the following general formula (I): ##STR1## wherein A represents a group --C.tbd.C-- or --CH.dbd.CH--, Y represents a group ##STR2## (in which R.sub.3 being a lower alkyl or alkoxy group or a halogen atom) or ##STR3## (in which R.sub.4 being a hydrogen atom or R.sub.3), and R.sub.1 and R.sub.2 represent individually a lower alkyl group, with a proviso that Y is other than the group ##STR4## when A means the group --CH.dbd.CH--, their preparation process and platelet aggregation inhibitors containing same.
    Type: Grant
    Filed: June 25, 1985
    Date of Patent: March 1, 1988
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Susumu Sato, Tadayuki Kouda, Tatsuhiko Katori
  • Patent number: 4588822
    Abstract: Disclosed are novel physiologically active substance SS 12538, process for its preparation and a novel microorganism producing the same.The novel physiologically active substance SS 12538 is represented by the following formula (I): ##STR1## in which R represents a hydrogen atom, a methyl group or an ethyl group. SS 12538 is obtained by inoculating a novel strain S 12538 in a nutrient-containing medium and cultivating aerobically.SS 12538 has excellent vasodilating action and antibiotic action against a certain gram positive bacteria and dermatophytes.
    Type: Grant
    Filed: April 6, 1983
    Date of Patent: May 13, 1986
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Junji Oono, Kenichi Yano, Junichi Sato, Tadayuki Kouda, Yoichiro Ogawa, Kouichi Yokoi, Toshiaki Nakashima
  • Patent number: 4450109
    Abstract: The specification describes novel thiazinobenzimidazole derivatives represented by the general formula: ##STR1## wherein R.sub.1, R.sub.2 and X represent a wide variety of substituent groups respectively. The above thiazinobenzimidazole derivatives may be prepared by reacting corresponding 2-hydroxymethyl thiazinobenzimidazole derivatives with corresponding reactive derivatives of carboxylic acid or halogenide or by reacting 2-p-toluenesulfonyloxymethyl-thiazinobenzimidazole derivatives with sodium azides, thiols, phenols or amines. The above thiazinobenzimidazole derivatives wherein X is OH may be prepared by reducing their corresponding 2-alkoxycarbonyl derivatives. Where X represents a p-toluenesulfonyloxy group, the thiazinobenzimidazole derivatives may be obtained by reacting corresponding 2-hydroxymethyl-thiazinobenzimidazole derivatives with p-toluenesulfonyl chloride.
    Type: Grant
    Filed: September 13, 1982
    Date of Patent: May 22, 1984
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Hiromichi Eto, Teruo Kohmoto, Tadayuki Kouda, Youichiro Ogawa, Susumu Sato, Tadayuki Kuraishi, Toshiaki Nakashima
  • Patent number: 4369309
    Abstract: The specification describes novel thiazinobenzmidazole derivatives represented by the general formula: ##STR1## wherein R.sub.1, R.sub.2 and X represent a wide variety of substituent groups respectively. The above thiazinobenzimidazole derivatives may be prepared by reacting corresponding 2-hydroxymethyl thiazinobenzimidazole derivatives with corresponding reactive derivatives of carbonylic acid or halogenide or by reacting 2-p-toluenesulfonyloxymethyl-thiazinobenzimidazole derivatives with sodium azides, thiols, phenols or amines. The above thiazinobenzimidazole derivatives wherein X in OH may be prepared by reducing their corresponding 2-alkoxycarbonyl derivatives. Where X represents a p-toluenesulfonyloxy group, the thiazinobenzimidazole derivatives may be obtained by reacting corresponding 2-hydroxymethyl-thiazinobenzimidazole derivatives with p-toluenesulfonyl chloride.
    Type: Grant
    Filed: March 3, 1981
    Date of Patent: January 18, 1983
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Hiromichi Eto, Teruo Kohmoto, Tadayuki Kouda, Youichiro Ogawa, Susumu Sato, Tadayuki Kuraishi, Toshiaki Nakashima