Patents by Inventor Tadayuki Sasaki

Tadayuki Sasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidine compound and pharmaceutically acceptable salts thereof
    Patent number: 5358945
    Abstract: The present invention relates to pyrimidine compounds represented by the formula ##STR1## (wherein X is a substituted or a cyclic amino group and Y is a substituted amino group or a substituted carbonyl group) or their pharmaceutically acceptable salts, and a therapeutic agent for neurological diseases comprising the compounds.These compounds are useful for treatment of various disorders in nervous systems since they are effective on growth of neurons and promotion of the formation and elongation of neutrites.
    Type: Grant
    Filed: March 30, 1992
    Date of Patent: October 25, 1994
    Assignees: Mitsui Petrochemical Industries, Ltd., Mitsui Pharmaceuticals, Inc.
    Inventors: Akira Mizuchi, Ken Ikeda, Yuichiro Kokubun, Kazutoshi Horikomi, Tadayuki Sasaki, Akira Awaya, Ikuo Tomino, Masaharu Ishiguro, Takumi Kitahara, Noriaki Kihara
  • Pyrimidines and pharmaceutically acceptable salts thereof useful in treatment of neurological disorders
    Patent number: 5304555
    Abstract: This invention provides novel pyrimidines or their pharmaceutically acceptable salts thereof and process for preparation thereof. The novel compounds are useful for neurological diseases of the peripheral and central nervous systems of animals.
    Type: Grant
    Filed: October 19, 1990
    Date of Patent: April 19, 1994
    Assignees: Mitsui Petrochemical Industries, Ltd., Mitsui Pharmaceuticals, Inc.
    Inventors: Akira Awaya, Kazutoshi Horikomi, Tadayuki Sasaki, Hisashi Kobayashi, Akira Mizuchi, Takuo Nakano, Ikuo Tomino, Shintaro Araki, Mitsuyuki Takesue, Koji Kato, Keiichi Yokoyama
  • Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
    Patent number: 5264435
    Abstract: 2,6-di-, 2,4,6-, 2,5,6-tri- or 2,4,5,6-tetra-substituted pyrimidines, and 2,6-di-substituted pyridines. These compounds are useful for treatment of neurological deseases.
    Type: Grant
    Filed: May 26, 1992
    Date of Patent: November 23, 1993
    Assignee: Mitsui Petrochemical Industries, Ltd.
    Inventors: Akira Mizuchi, Kazutoshi Horikomi, Tadayuki Sasaki, Akira Awaya, Ikuo Tomino, Noriaki Kihara, Takumi Kitahara
  • 2,6-di,2,4,6-, 2,5,6-tri and 2,4,5,6-tetra-substituted pyrimidines, their pharmaceutically acceptable salts, pharmaceutical compositions containing same and their use in the treatment of neurological diseases
    Patent number: 5147876
    Abstract: 2,6-di-, 2,4,6-, 2,5,6-tri- or 2,4,5,6-tetra-substituted pyrimidines, and 2,6-di-substituted pyridines. These compounds are useful for treatment of neurological diseases.
    Type: Grant
    Filed: December 29, 1989
    Date of Patent: September 15, 1992
    Assignee: Mitsui Petrochemical Industries, Ltd.
    Inventors: Akira Mizuchi, Kazutoshi Horikomi, Tadayuki Sasaki, Akira Awaya, Ikuo Tomino, Mitsuyuki Takesue, Noriaki Kihara
  • Therapeutic agent for neurological diseases
    Patent number: 4959368
    Abstract: A pharmaceutical composition comprising a pyrimidine represented by the following formula ##STR1## wherein R.sup.1 represents a hydrogen atom, an acyl group having 2 to 4 carbon atoms, an alkoxycarbonyl group having 2 to 5 carbon atoms, an alkoxycarbonylmethyl group having 3 to 5 carbon atoms, a 3,4-dimethoxybenzoyl group or a 3,4-methylenedioxybenzyl group,R.sup.2 represents a hydrogen atom, an amino group, a monoalkylamino group having 1 to 4 carbon atoms, an alkoxy group having 1 to 5 carbon atoms or an alkoxycarbonyl group having 2 to 4 carbon atoms,R.sup.3 represents a hydrogen atom, an alkoxycarbonyl group having 2 to 4 carbon atoms, a dialkylaminocarbonyl group having 1 to 9 carbon atoms in each alkyl moiety, an alkoxy group having 1 to 5 carbon atoms, or a hydroxyethyl group, R.sup.2 and R.sup.3, together with the carbon atoms to which they are bonded, may form a 5- to 7-membered carbocyclic ring or a heterocyclic ring having N, O or S as the hetero atom, and R.sup.
    Type: Grant
    Filed: October 22, 1987
    Date of Patent: September 25, 1990
    Assignees: Mitsui Petrochemical Industries Ltd., Mitsui Pharmaceuticals, Inc.
    Inventors: Akira Awaya, Takuo Nakano, Hisashi Kobayashi, Ken E. Tan, Kazutoshi Horikomi, Tadayuki Sasaki, Keiichi Yokoyama, Hiroyasu Ohno, Kozi Kato, Takumi Kitahara, Ikuo Tomino, Shigeru Isayama