Patents by Inventor Tadeusz J. Wiktor

Tadeusz J. Wiktor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immune response to virus induced by anti-idiotype antibodies
    Patent number: 4731237
    Abstract: A method of inducing an immunological response in a host to a virus is provided employing anti-idiotype antibodies that present an internal image of a viral antigen to the host. Anti-idiotype antibodies and the cell lines that produce such antibodies are also provided.
    Type: Grant
    Filed: November 7, 1983
    Date of Patent: March 15, 1988
    Assignee: The Wistar Institute
    Inventors: Kevin J. Reagan, Tadeusz J. Wiktor, Hilary Koprowski
  • Process for the large scale production of rabies vaccine
    Patent number: 4664912
    Abstract: In the large-scale production of rabies vaccine a cell stock comprising a VERO cell strain and a liquid nutritive medium containing serum and microcarriers suspended therein is successively passed into biogenerators of increasing volume. The last of the passages is carried out in a biogenerator having a volume of at least 150 liters. The liquid nutritive medium is drawn off at the end of the final passage and replaced with a serum-free liquid nutritive medium. The cell stock is inoculated in the last passage biogenerator with virus which is allowed to develop. The virus is then cultured, withdrawn and filtered. The filtered liquid suspension is then ultrafiltered, with inactivated beta-propiolactone and purified by zonal centrifugation or chromatography.
    Type: Grant
    Filed: October 1, 1984
    Date of Patent: May 12, 1987
    Inventors: Tadeusz J. Wiktor, Bernard J. Fanget, Pierre Fournier, Bernard J. Montagnon