Patents by Inventor Tae Hyun Kang
Tae Hyun Kang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11958904Abstract: In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.Type: GrantFiled: June 14, 2021Date of Patent: April 16, 2024Assignee: Research Development FoundationInventors: George Georgiou, Chang-Han Lee, Tae Hyun Kang
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Publication number: 20240116005Abstract: The present invention relates to a method for preparing a 3D biological bilayer membrane structure in a physiological buffer solution and a 3D biological bilayer membrane structure using the same, and more particularly, to a method for preparing a 3D biological bilayer membrane structure that is tightly sealed even under physiological ionic conditions by applying pressure during electroformation to improve a membrane fusion function, and a 3D biological bilayer membrane structure using the same.Type: ApplicationFiled: September 29, 2023Publication date: April 11, 2024Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Tae Song KIM, Dong Hyun KANG, Bong Kyu KIM
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Publication number: 20240119851Abstract: The present invention relates to a method and system for providing language learning services. The method of providing language learning services, according to the present invention, the method may include: activating, in response to receiving an input for acquiring a learning target image through a user terminal, a camera of the user terminal; specifying at least a portion of an image taken by the camera as the learning target image; receiving language learning information for the learning target image from a server; providing the language learning information to the user terminal; and storing, based on a request for storing of the language learning information, the language learning information in association with the learning target image, such that the learning target image is used in conjunction with learning of the language learning information.Type: ApplicationFiled: September 29, 2023Publication date: April 11, 2024Inventors: Eun Young LEE, Min Jung KIM, Yeun Hee KANG, Bong Hyun CHOI, Tae Un KIM, Soo Hyun LEE, Young Ho KIM, Chan Kyu CHOI, Jin Mo KU, Jong Won KIM
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Publication number: 20240114778Abstract: The present disclosure relates to an organic electroluminescent compound, a plurality of host materials, and an organic electroluminescent device comprising the same. By comprising the compound according to the present disclosure or by comprising a specific combination of compounds according to the present disclosure as a plurality of host materials, it is possible to produce an organic electroluminescent device having improved driving voltage, luminous efficiency, and/or lifetime properties compared to the conventional organic electroluminescent devices.Type: ApplicationFiled: August 14, 2023Publication date: April 4, 2024Inventors: So-Young JUNG, Hyo-Nim SHIN, Seung-Hyun YOON, Hyun-Ju KANG, Ye-Jin JEON, Tae-Jun HAN, Mi-Ja LEE, Dong-Gil KIM, Sang-Hee CHO
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Patent number: 11944998Abstract: A method of fabricating a capacitive micromachined ultrasonic transducer (CMUT) according to one aspect of the present invention may include forming, on a semiconductor substrate, a first region implanted with impurity ions at a first average concentration and a second region implanted with no impurity ions or implanted with the impurity ions at a second average concentration lower than the first average concentration, forming an insulating layer by oxidizing the semiconductor substrate wherein the insulating layer includes a first oxide layer having a first thickness on at least a part of the first region and a second oxide layer having a second thickness smaller than the first thickness on at least a part of the second region, and forming a membrane layer on the insulating layer such that a gap is defined between the second oxide layer and the membrane layer.Type: GrantFiled: March 18, 2020Date of Patent: April 2, 2024Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Byung Chul Lee, Dong-Hyun Kang, Jin soo Park, Tae Song Kim
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Publication number: 20240080450Abstract: The present invention discloses an image decoding method, the method including generating a candidate list including motion information derived from a spatial neighboring block and a temporal neighboring block adjacent to a current block; deriving motion information of the current block using the candidate list; generating a prediction block of the current block using the derived motion information; and updating the derived motion information in a motion information list, wherein the generating of the candidate list is performed in such a manner as to include at least one information of the motion information included in the updated motion information list in a block decoded before the current block.Type: ApplicationFiled: November 2, 2023Publication date: March 7, 2024Applicants: Electronics and Telecommunications Research Institute, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventors: Jung Won KANG, Ha Hyun LEE, Sung Chang LIM, Jin Ho LEE, Hui Yong KIM, Gwang Hoon PARK, Tae Hyun KIM, Dae Young LEE
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Publication number: 20210347891Abstract: In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.Type: ApplicationFiled: June 14, 2021Publication date: November 11, 2021Applicant: Research Development FoundationInventors: George GEORGIOU, Chang-Han LEE, Tae Hyun KANG
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Patent number: 11059892Abstract: In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.Type: GrantFiled: August 11, 2018Date of Patent: July 13, 2021Assignee: Research Development FoundationInventors: George Georgiou, Chang-Han Lee, Tae Hyun Kang
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Publication number: 20190048078Abstract: In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.Type: ApplicationFiled: August 11, 2018Publication date: February 14, 2019Inventors: George GEORGIOU, Chang-Han LEE, Tae Hyun KANG
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Patent number: 9771426Abstract: Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds Fc?RIIa, but that is significantly reduced for binding to the highly homologous Fc?RIIb receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.Type: GrantFiled: December 31, 2014Date of Patent: September 26, 2017Assignee: Research Development FoundationInventors: George Georgiou, Sang Taek Jung, William Kelton, Tae Hyun Kang
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Publication number: 20150183873Abstract: Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds Fc?RIIa, but that is significantly reduced for binding to the highly homologous Fc?RIIb receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.Type: ApplicationFiled: December 31, 2014Publication date: July 2, 2015Applicant: RESEARCH DEVELOPMENT FOUNDATIONInventors: George GEORGIOU, Sang Taek JUNG, William KELTON, Tae Hyun KANG
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Patent number: 8952132Abstract: Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds Fc?RIIa, but that is significantly reduced for binding to the highly homologous Fc?RIIb receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.Type: GrantFiled: February 6, 2012Date of Patent: February 10, 2015Assignee: Research Development FoundationInventors: George Georgiou, Sang Taek Jung, William Kelton, Tae Hyun Kang
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Publication number: 20120208238Abstract: Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds Fc?RIIa, but that is significantly reduced for binding to the highly homologous Fc?RIIb receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.Type: ApplicationFiled: February 6, 2012Publication date: August 16, 2012Inventors: George Georgiou, Sang Taek Jung, William Kelton, Tae Hyun Kang
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Publication number: 20090061383Abstract: Disclosed is a dental clinical instrument for the diagnosis of periodontal disease. The dental clinical instrument comprises a main body held by hand to apply a force during diagnosis, a probe having a front portion bent downward to be inserted into a periodontal site to be diagnosed and a rear portion coupled to the main body to allow the front portion to be movable up and down, and a measurement indicator positioned toward the probe on the main body to display a change in the location of the probe so that a user can discern the force applied to the probe wherein the measurement indicator displays the force applied to the probe when the probe elastically moves up and down with respect to the main body in a state where the probe is positioned at the periodontal site. The measurement indicator is disposed at a front end portion of the main body.Type: ApplicationFiled: August 26, 2008Publication date: March 5, 2009Inventor: Tae Hyun Kang