Abstract: The present disclosure relates to a composition for antiobesity, which contains a Gynostemma pentaphyllum tea or a Gynostemma pentaphyllum tea extract as an active ingredient. The composition of the present disclosure, which contains a Gynostemma pentaphyllum tea or a Gynostemma pentaphyllum tea extract as an active ingredient, is effective for preventing, alleviating or treating diabetes, obesity, muscle loss, etc. since it exhibits the efficacy of increasing AMPK activity, promoting beta oxidation, promoting glucose uptake, etc. In addition, since the composition of the present disclosure is derived from a natural product, it can be safely used as a drug, food, etc. without side effects.