Publication number: 20240400565
Abstract: Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein wherein m, n, p, R1, R2, R3, L1, L2, L3, R4, X1, X2, X3, and X4 are as defined herein. Also provided are methods of preparing compounds of formula (II), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided are methods of inhibiting APOL1 and methods of treating an APOL1-mediated disease, disorder, or condition in an individual.
Type:
Application
Filed:
March 26, 2024
Publication date:
December 5, 2024
Inventors:
Patrick Sang Tae LEE, Todd Jonathan August EWING, Adam Neil REID, Christopher Joseph SINZ, Birong ZHANG, Sarah M. BRONNER, David John MORGANS, Jr., Maarten HOEK, Victoria Anne ASSIMON, Chris ZIEBENHAUS, Alexander Wayne SCHAMMEL