Abstract: A watermarking method for smart contract according to an embodiment of the present disclosure comprises compiling a source code of a smart contract to create a contract creation bytecode and a runtime bytecode; generating a control flow graph including a plurality of byte regions based on the runtime bytecode; setting opcode groups by grouping consecutive opcodes in an opcode list in the plurality of byte regions of the generated control flow graph so that a sum of gas costs for the consecutive opcodes is greater than or equal to a preset gas cost value; extracting a watermarkable byte region based on the set opcode groups; determining watermarking bytes, in which a watermark is to be embed in the watermarkable byte region, to embed the watermark and storing location information of the determined watermarking bytes; hashing fingerprint information including information on the watermark and the location information of the watermarking bytes to create a fingerprint; and embedding the created fingerprint in the

Abstract: The present invention discloses cell penetrating peptides (CPP or membrane translocating peptide) and their conjugates with cargo molecules. The peptides are useful as drug delivery systems, particularly as delivery vehicles for nucleotide-based therapeutics, such as polynucleotides, oligonucleotides and peptide nucleic acids. A CPPs of the invention provides a balance between good cell entry efficiency and low toxicity and comprises three contiguous domains: the central one being hydrophobic and the flanking ones consisting of arginine and aminohexanoic acid or beta-alanine residues. The hydrophobic domain contains a sequence selected from YQFLI, YRFLI, IQFLI and IRFLI.

Abstract: The present invention discloses cell penetrating peptides (CPP or membrane translocating peptide) and their conjugates with cargo molecules. The peptides are useful as drug delivery systems, particularly as delivery vehicles for nucleotide-based theraputics, such as polynucleotides, oligonucleotides and peptide nucleic acids. A CPPs of the invention provides a balance between good cell entry efficency and low toxicity and comprises three contiguous domains: the central one being hydrophobic and the flanking ones consisting of arginine and aminohexanoic acid or beta-alanine residues. The hydrophobic domain contains a sequence selected from YQFLI, YRFLI, IQFLI and IRFLI.