Patents by Inventor Tae-Bo Sim

Tae-Bo Sim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoquinoline derivatives, preparation method thereof and pharmaceutical composition comprising the same
    Patent number: 8049014
    Abstract: Provided are a novel aminoquinoline compound represented by Formula 1 or a pharmaceutically acceptable salt thereof, preparation method thereof, and a pharmaceutical composition for preventing or treating cutaneous cancer, comprising the aminoquinoline compound or pharmaceutically acceptable salt thereof. Since the compound of Formula 1 exhibits excellent anti-proliferative effect on melanoma tumor cells, it is useful for preventing or treating cutaneous cancer. wherein R1, R2, and R3 are defined in the specification.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: November 1, 2011
    Assignee: Korea Institute of Science and Technology
    Inventors: Kyung-Ho Yoo, Dong-Jin Kim, Bong-Soo Nam, Chang-Hyun Oh, So-Ha Lee, Seung-Joo Cho, Tae-Bo Sim, Jung-Mi Hah
  • AMINOQUINOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20100249182
    Abstract: Provided are a novel aminoquinoline compound represented by Formula 1 or a pharmaceutically acceptable salt thereof, preparation method thereof, and a pharmaceutical composition for preventing or treating cutaneous cancer, comprising the aminoquinoline compound or pharmaceutically acceptable salt thereof. Since the compound of Formula 1 exhibits excellent anti-proliferative effect on melanoma tumor cells, it is useful for preventing or treating cutaneous cancer. wherein R1, R2, and R3 are defined in the specification.
    Type: Application
    Filed: May 19, 2009
    Publication date: September 30, 2010
    Inventors: Kyung-Ho YOO, Dong-Jin KIM, Bong-Soo NAM, Chang-Hyun OH, So-Ha LEE, Seung-Joo CHO, Tae-Bo SIM, Jung-Mi HAH
  • Fumagillol derivative and the medical use thereof
    Publication number: 20070149613
    Abstract: The disclosure relates to a fumagillol compound which can be usefully used not only as an angiogenesis inhibiting agent showing a superior angiogenesis inhibitory effect with less toxicity, but also as a cancer metastasis inhibitor and a therapeutic agent against cancer and other various inflammatory diseases such as rheumatic disease, psoriasis, etc., and diabetic retinopathy related to angiogenesis, and also a method for preparing the same.
    Type: Application
    Filed: November 21, 2006
    Publication date: June 28, 2007
    Inventors: Cheol-Kyu Han, Jeong-Hyeok Yoon, Seung-Moak Kim, Nam-Doo Kim, Byung-Ha Chang, Jee-Young Lee, Tae-Bo Sim
  • Fumagillol derivatives and preparing method thereof
    Publication number: 20060276512
    Abstract: The disclosure relates to a fumagillol compound which can be usefully used not only as an angiogenesis inhibiting agent showing a superior angiogenesis inhibitory effect with less toxicity, but also as a cancer metastasis inhibitor and a therapeutic agent against cancer and other various inflammatory diseases such as rheumatic disease, psoriasis, etc., and diabetic retinopathy related to angiogenesis, and also a method for preparing the same.
    Type: Application
    Filed: July 26, 2006
    Publication date: December 7, 2006
    Inventors: Cheol-Kyu Han, Jeong-Hyeok Yoon, Seung-Moak Kim, Nam-Doo Kim, Byung-Ha Chang, Jee-Young Lee, Tae-Bo Sim
  • Fumagillol derivatives and preparing method thereof
    Patent number: 7087768
    Abstract: The disclosure relates to a fumagillol compound which can be usefully used not only as an angiogenesis inhibiting agent showing a superior angeogenesis inhibitory effect with less toxicity, but also as a cancer metastasis inhibitor and a therapeutic agent against cancer and other various inflammatory diseases such as rheumatic disease, psoriasis, etc., and diabetic retinopathy related to angeogeneois, and also a method for preparing the same.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: August 8, 2006
    Assignee: Equispharm Co., Ltd.
    Inventors: Cheol-Kyu Han, Jeong-Hyeok Yoon, Seung-Moak Kim, Nam-Doo Kim, Byung-Ha Chang, Jee-Young Lee, Tae-Bo Sim
  • Fumagillol derivatives and preparing method thereof
    Publication number: 20040242681
    Abstract: The disclosure relates to a fumagillol compound which can be usefully used not only as an angiogenesis inhibiting agent showing a superior angeogenesis inhibitory effect with less toxicity, but also as a cancer metastasis inhibitor and a therapeutic agent against cancer and other various inflammatory diseases such as rheumatic disease, psoriasis, etc., and diabetic retinopathy related to angeogeneois, and also a method for preparing the same.
    Type: Application
    Filed: March 23, 2004
    Publication date: December 2, 2004
    Inventors: Cheol-Kyu Han, Jeong-Hyeok Yoon, Seung-Moak Kim, Nam-Doo Kim, Byung-Ha Chang, Jee-Young Lee, Tae-Bo Sim