Patents by Inventor Taher Nassar

Taher Nassar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLEYLCYSTEINEAMIDE OR DERIVATIVES THEREOF AND THEIR USE IN THERAPY
    Publication number: 20230293459
    Abstract: The subject-matter of the present application concerns oleylcysteineamide (OCA) and OCA derivatives as active agents and their use in the treatment of inflammatory disorders as well as in treating skin whitening.
    Type: Application
    Filed: August 5, 2021
    Publication date: September 21, 2023
    Inventors: Simon BENITA, Taher NASSAR, Riki PERLMAN, Dina BEN YEHUDA, Ihab ABD-ELRAHMAN, Noha KHAIRI
  • SELF-EMULSIFYING DRUG DELIVERY SYSTEMS FOR DELIVERY OF LIPOPHILIC COMPOUNDS
    Publication number: 20220202712
    Abstract: The present disclosure provides self-emulsifying drug delivery systems for delivery of lipophilic compounds, compositions, kits and unit dosage forms thereof, as well as processes for their preparation.
    Type: Application
    Filed: April 7, 2020
    Publication date: June 30, 2022
    Inventors: Simon Benita, Taher Nassar
  • CB1R RECEPTOR BLOCKERS WITH ACYCLIC BACKBONES
    Publication number: 20220119365
    Abstract: The invention generally concerns a novel class of CB 1 receptor binding molecules and uses thereof.
    Type: Application
    Filed: January 15, 2020
    Publication date: April 21, 2022
    Inventors: Simon Benita, Taher Nassar, Joseph Tam, Shira Hirsh
  • DRUG DELIVERY SYSTEMS
    Publication number: 20210128534
    Abstract: A novel platform for manufacturing storage stable and effective drug delivery systems.
    Type: Application
    Filed: February 26, 2019
    Publication date: May 6, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon BENITA, Taher NASSAR, Leslie REBIBO, Amit BADIHI
  • OPHTHALMIC COMPOSITIONS
    Publication number: 20190209466
    Abstract: An ophthalmic composition useful for the treatment of bacterial eye infections is provided. The ophthalmic composition includes the suspension of particles of active anti-bacterial agent in a gelled matrix.
    Type: Application
    Filed: September 3, 2017
    Publication date: July 11, 2019
    Applicants: DEXCEL PHARMA TECHNOLOGIES LTD., YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Simon BENITA, Taher NASSAR
  • Pt (IV) derivatives and nanocarriers comprising them
    Patent number: 10239903
    Abstract: Provided are Pt (IV) lipophilic derivatives for improved drug performance in cancer therapy, as well as nanocarriers including the same.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: March 26, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon Benita, Taher Nassar, Dan Gibson, Aiman Abu Ammar
  • Nanoencapsulation of hydrophilic active compounds
    Patent number: 9839617
    Abstract: Provided is a nanoparticle including a water-soluble protein, a glucan and a hydrophilic active agent, the glucan being at least partially cross-linked by a metaphosphate.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: December 12, 2017
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon Benita, Taher Nassar, Liat Kochavi-Soudry
  • PT (IV) DERIVATIVES AND NANOCARRIERS COMPRISING THEM
    Publication number: 20170081352
    Abstract: Provided are Pt (IV) lipophilic derivatives for improved drug performance in cancer therapy, as well as nanocarriers including the same.
    Type: Application
    Filed: April 30, 2015
    Publication date: March 23, 2017
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon BENITA, Taher NASSAR, Dan GIBSON, Aiman Abu AMMAR
  • NANOENCAPSULATION OF HYDROPHILIC ACTIVE COMPOUNDS
    Publication number: 20160361267
    Abstract: Provided is a nanoparticle including a water-soluble protein, a glucan and a hydrophilic active agent, the glucan being at least partially cross-linked by a metaphosphate.
    Type: Application
    Filed: January 26, 2015
    Publication date: December 15, 2016
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon BENITA, Taher NASSAR, Liat KOCHAVI-SOUDRY
  • NANO DELIVERY SYSTEMS FOR SIRNA
    Publication number: 20160317460
    Abstract: The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nanospray techniques.
    Type: Application
    Filed: June 14, 2016
    Publication date: November 3, 2016
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LT
    Inventors: Simon BENITA, Orit AMSALEM, Taher NASSAR
  • Nano delivery systems for siRNA
    Patent number: 9421173
    Abstract: The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nano spray techniques.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: August 23, 2016
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Simon Benita, Orit Amsalem, Taher Nassar
  • MICRO-PARTICULATED NANOCAPSULES CONTAINING LOPINAVIR WITH ENHANCED ORAL BIOAVAILABILITY AND EFFICACY
    Publication number: 20160235749
    Abstract: The present disclosure provides controlled-release delivery systems for oral delivery of active agents, e.g. lopinavir, comprising micro-particulated with enhanced oral bioavailability and efficacy, which may be used for treating HIV.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 18, 2016
    Inventors: Simon BENITA, Taher NASSAR
  • NANOPARTICLES FOR DERMAL AND SYSTEMIC DELIVERY OF DRUGS
    Publication number: 20160228497
    Abstract: The present invention relates to a poly(lactic glycolic) acid (PLGA) nanoparticle associated with therapeutic agents for a variety of therapeutic applications.
    Type: Application
    Filed: April 14, 2016
    Publication date: August 11, 2016
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Simon BENITA, Taher NASSAR, Nour KARRA, Amit BADIHI
  • Nano delivery systems for siRNA
    Patent number: 9387180
    Abstract: The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nano spray techniques.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: July 12, 2016
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Simon Benita, Orit Amsalem, Taher Nassar
  • CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF
    Publication number: 20160120995
    Abstract: Novel chemical conjugates derived from unsaturated fatty acids and therapeutically active agents, are disclosed. The chemical conjugates are designed and characterized as COX-2 and/or 5-LOX inhibitors and are useful in the treatment of inflammatory diseases, dermatitis and disorders such as Alzheimer's disease, Parkinson's disease, asthma, osteoarthritis, rheumatoid arthritis, pain, primary dysmenorrhea, Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: September 9, 2015
    Publication date: May 5, 2016
    Inventor: Taher NASSAR
  • SKIN CARE PRODUCTS COMPRISING SUBSTITUTED HYDROXYPROLINE WITH UNSATURATED FATTY ACIDS DERIVATIVES
    Publication number: 20160113904
    Abstract: Disclosed is a method for treating or preventing pathological or non-pathological skin conditions, disorders or diseases comprising administering a conjugate of proline, hydroxyproline, or a salt thereof, conjugated with a fatty acid.
    Type: Application
    Filed: May 28, 2014
    Publication date: April 28, 2016
    Inventors: Taher NASSAR, Michal OLSHANSKY
  • NANO DELIVERY SYSTEMS
    Publication number: 20150037427
    Abstract: The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nano spray techniques.
    Type: Application
    Filed: September 20, 2012
    Publication date: February 5, 2015
    Inventors: Simon Benita, Orit Amsalem, Taher Nassar
  • NOVEL CONJUGATES OF POLYUNSATURATED FATTY ACIDS WITH AMINES AND THERAPEUTIC USES THEREOF
    Publication number: 20140121260
    Abstract: The present application discloses conjugates comprising an aminic moiety covalently linked to a hydrophobic moiety, through an amidic bond, which are selective inhibitors of COX-2 enzyme and can be beneficially used in the treatment of various inflammatory disease or disorder and cancer.
    Type: Application
    Filed: January 6, 2014
    Publication date: May 1, 2014
    Applicant: MedWell Laboratories Ltd.
    Inventors: Taher NASSAR, Raiyn Nureldin, Rayan Anwar
  • Derivatives of taxol and closely related compounds
    Patent number: 8586625
    Abstract: A cytotoxic composition in which two moieties are conjugated covalently. A first moiety is a tax moiety, selected from the group consisting of taxanes, taxane derivatives, and or other closely relative compounds. A second moiety is an acid moiety selected from the group consisting of lipoic acid, acetylcysteine, compounds having an acidic group.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: November 19, 2013
    Inventors: Anwar Rayan, Taher Nassar
  • CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF
    Publication number: 20130158070
    Abstract: Novel chemical conjugates derived from unsaturated fatty acids and therapeutically active agents, are disclosed. The chemical conjugates are designed and characterized as COX-2 and/or 5-LOX inhibitors and are useful in the treatment of inflammatory diseases and disorders such as Alzheimer's disease, Parkinson's disease, asthma, osteoarthritis, rheumatoid arthritis, pain, primary dysmenorrhea, Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: September 6, 2011
    Publication date: June 20, 2013
    Inventor: Taher Nassar