Abstract: Provided is a method for fabricating a microstructure. The method includes disposing an X-ray mask on photosensitive material and exposing the photosensitive material by radiating X-rays to the photosensitive material, etching the exposed photosensitive material, forming a mold having a micro-pattern by filing the etched photosensitive material with metal, forming a mold module by combining a plurality of molds, and forming a microstructure using the mold module.

Abstract: A droplet mixing apparatus can be applied for use with a variety of liquids, can provide a mixing speed of hundreds of nl/s by adjusting an opening/closing time of a solenoid valve, can effectively mix droplets, and can reduce a reaction time when applied to clinical appliances that utilize expensive liquids. The droplet mixing apparatus includes a plurality of pressure containers storing liquids that are to be dispensed, a plurality of solenoid valves that are respectively connected to the pressure containers to dispense the liquids fed from the pressure containers into a mixing container, and a control unit that controls the solenoid valves such that the solenoid valves are either simultaneously opened or alternately opened and closed.

Abstract: The present invention relates to a pump and pumping system for a microfluidic lab-on-a-chip, and a fabricating method thereof. An exemplary embodiment of the present invention provides a method of fabricating a pump for microfluidic lab-on-a-chips, the method including: infiltrating PDMS (polydimethylsiloxane) solution into a porous lump of water-soluble material; performing soft baking of the porous lump of water-soluble material containing the PDMS solution; and dissolving the porous lump of water-soluble material via water to obtain a porous PDMS structure.

Abstract: Provided is a method for fabricating a microstructure. The method includes disposing an X-ray mask on photosensitive material and exposing the photosensitive material by radiating X-rays to the photosensitive material using a side exposure scheme, etching the exposed photosensitive material, forming a mold having a micro-pattern by filing the etched photosensitive material with metal, forming a mold module by combining a plurality of molds, and forming a microstructure using the mold module.

Abstract: A droplet mixing apparatus can be applied for use with a variety of liquids, can provide a mixing speed of hundreds of nl/s by adjusting an opening/closing time of a solenoid valve, can effectively mix droplets, and can reduce a reaction time when applied to clinical appliances that utilize expensive liquids. The droplet mixing apparatus includes a plurality of pressure containers storing liquids that are to be dispensed, a plurality of solenoid valves that are respectively connected to the pressure containers to dispense the liquids fed from the pressure containers into a mixing container, and a control unit that controls the solenoid valves such that the solenoid valves are either simultaneously opened or alternately opened and closed.

Abstract: The present invention is directed to a microfluidic biochip based on an agglutination reaction that is frequently used in qualitative typing in the diagnostic medicine field by realizing a specimen inlet, a reagent inlet, a split microchannel, transfer microchannels, a chaos micromixer, a reaction microchamber, a microfilter, a passive microvalve, and an outlet on a plastic microchip. Particularly, the biochip of the present invention is characterized in that portability thereof is superior and a small amount (about 1 ?l) of each of a specimen and a reagent is used. In addition, the biochip of the present invention can be cheaply made through conventional photolithography, electroplating, injection molding, and bonding. Therefore, by utilizing the microfluidic biochip for blood typing according to the present invention, a point-of-care diagnosis for performing blood typing based on an agglutination reaction at any place becomes possible.

Abstract: The present invention relates to a pump and pumping system for a microfluidic lab-on-a-chip, and a fabricating method thereof. An exemplary embodiment of the present invention provides a method of fabricating a pump for microfluidic lab-on-a-chips, the method including: infiltrating PDMS (polydimethylsiloxane) solution into a porous lump of water-soluble material; performing soft baking of the porous lump of water-soluble material containing the PDMS solution; and dissolving the porous lump of water-soluble material via water to obtain a porous PDMS structure.

Abstract: The present invention is directed to a microfluidic biochip based on an agglutination reaction that is frequently used in qualitative typing in the diagnostic medicine field by realizing a specimen inlet, a reagent inlet, a split microchannel, transfer microchannels, a chaos micromixer, a reaction microchamber, a microfilter, a passive microvalve, and an outlet on a plastic microchip. Particularly, the biochip of the present invention is characterized in that portability thereof is superior and a small amount (about 1 ?l) of each of a specimen and a reagent is used. In addition, the biochip of the present invention can be cheaply made through conventional photolithography, electroplating, injection molding, and bonding. Therefore, by utilizing the microfluidic biochip for blood typing according to the present invention, a point-of-care diagnosis for performing blood typing based on an agglutination reaction at any place becomes possible.

Abstract: Disclosed is a method of producing a mold for preparing a hydrophobic polymer substrate including forming an adhesion enhancer on a substrate, forming a first conductive layer on the adhesion enhancer, adhering a predetermined patterned hydrophobic template on the first conductive layer, forming a second conductive layer on the template to prepare a template assembly, metal electroplating on the template assembly to form a metal plating layer on the template assembly, and removing the first conductive layer, the second conductive layer, the adhesion enhancer, and the template from the template assembly.

Abstract: Disclosed is a method of producing a hydrophobic polymer substrate including coating a curable photopolymer composition on a substrate, locating a micro- and nano-patterned hydrophobic template on the coated substrate, curing the curable photopolymer composition to prepare a curable photopolymer layer, and separating the curable photopolymer layer from the hydrophobic template.