Patents by Inventor Tai-Jay Chang

Tai-Jay Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human ARCAP transgenic mouse
    Patent number: 10349638
    Abstract: A non-human transgenic animal that contains in its genome a nucleic acid encoding human ARCAP operably linked to a liver-specific promoter. The transgenic animal expresses the human ARCAP protein and develops tumors of the liver, spleen, abdomen, or lymph. Also provided is a cell line derived from the non-human transgenic animal expressing the human ARCAP gene. Further provided is a method for producing a transgenic mouse by micro-injecting into a fertilized mouse oocyte a vector that contains a human ARCAP cDNA operably linked to a liver-specific promoter and transferring the micro-injected mouse oocyte into a foster mouse.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: July 16, 2019
    Inventor: Tai-Jay Chang
  • HUMAN ARCAP TRANSGENIC MOUSE
    Publication number: 20190014756
    Abstract: A non-human transgenic animal that contains in its genome a nucleic acid encoding human ARCAP operably linked to a liver-specific promoter. The transgenic animal expresses the human ARCAP protein and develops tumors of the liver, spleen, abdomen, or lymph. Also provided is a cell line derived from the non-human transgenic animal expressing the human ARCAP gene. Further provided is a method for producing a transgenic mouse by micro-injecting into a fertilized mouse oocyte a vector that contains a human ARCAP cDNA operably linked to a liver-specific promoter and transferring the micro-injected mouse oocyte into a foster mouse.
    Type: Application
    Filed: July 14, 2017
    Publication date: January 17, 2019
    Inventor: Tai-Jay Chang
  • Androgen receptor complex-associated protein
    Patent number: 7083935
    Abstract: The invention relates to new proteins that bind to and aide the transactivation activity of androgen receptors, and nucleic acids encoding them.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: August 1, 2006
    Assignee: Veterans General Hospital
    Inventor: Tai-Jay Chang
  • Nucleic acid encoding androgen receptor complex-associated protein
    Patent number: 6974683
    Abstract: The invention relates to new proteins that bind to and aide the transactivation activity of androgen receptors, and nucleic acids encoding them.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: December 13, 2005
    Assignee: Veterans General Hospital
    Inventor: Tai-Jay Chang
  • Androgen receptor complex-associated protein
    Publication number: 20050272099
    Abstract: The invention relates to new proteins that bind to and aide the transactivation activity of androgen receptors, and nucleic acids encoding them.
    Type: Application
    Filed: July 26, 2005
    Publication date: December 8, 2005
    Inventor: Tai-Jay Chang
  • Treating breast cancer
    Publication number: 20040115656
    Abstract: New androgen receptor down-regulatory-associated proteins (i.e., ARDAPs) that bind to and reduce the transactivation activity of androgen receptors, and nucleic acids encoding them.
    Type: Application
    Filed: December 16, 2002
    Publication date: June 17, 2004
    Inventor: Tai-Jay Chang
  • Androgen receptor complex-associated protein
    Publication number: 20030099976
    Abstract: Primers and probes for detecting the expression of the human ARCAP gene.
    Type: Application
    Filed: July 25, 2002
    Publication date: May 29, 2003
    Inventor: Tai-Jay Chang
  • Transgenic animals expressing androgen receptor complex-associated protein
    Publication number: 20030082721
    Abstract: Transgenic animals expressing an androgen receptor complex-associated protein gene. These animals serve as models for developing drugs to treat cancer, e.g., liver cancer.
    Type: Application
    Filed: July 25, 2002
    Publication date: May 1, 2003
    Inventor: Tai-Jay Chang
  • Androgen receptor complex-associated protein
    Publication number: 20030054438
    Abstract: The invention relates to new proteins that bind to and aide the transactivation activity of androgen receptors, and nucleic acids encoding them.
    Type: Application
    Filed: February 12, 2001
    Publication date: March 20, 2003
    Inventor: Tai-Jay Chang