Abstract: A method is provided for making transgenic animals by transferring DNA into embryo by subjecting the mixture of the DNA to be transferred and the embryo to an electric discharge.

Abstract: A method is provided for transferring genes into cells which comprises the step of subjecting the mixture of genes to be transferred and the target cells to an electric treatment.

Abstract: A high-voltage biological macromolecule transfer and cell fusion system for transforming a low input voltage into a high-voltage discharge output. The system comprises voltages source means, a frequency source means, a burst control means, a cycle control means, a pulse generating means, a pulse control means, and a high-voltage discharge generating means. The voltages source means is adapted to transform the generally low input voltage into a system-enabling control signal, a direct-current base voltage, and a generally low-voltage direct-current system voltage. The frequency source means generates system-enabling control pulses. The burst control means is provided to control the burst time of the high-voltage discharge output. The cycle control means is adapted to control the number of cycles in the high-voltage discharge output. The pulse generating means generates the pulses that evolve into the high-voltage discharge output.