Patents by Inventor Tai W. Wong

Tai W. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC COMBINATION OF A PANHER/VEGFR2 KINASE INHIBITOR AND A PLATINUM COMPOUND
    Publication number: 20100136137
    Abstract: This invention relates to a synergistic therapeutic combination of anti-cancer compounds which comprises a) a panHER/VEGFR2 kinase inhibitor, and b) a platinum compound, and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use. The invention also relates to treating certain cancers utilizing the combination of the invention.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 3, 2010
    Inventors: Tai W. Wong, Jean Soria, Guido Kroemer
  • Transgenic non-human mammals expressing constitutively activated tyrosine kinase receptors
    Patent number: 7265260
    Abstract: A transgenic non-human mammal whose germ cells and somatic cells contain a constructively activated tyrosine kinase receptor introduced into the mammal, or an ancestor of the mammal, at an embryonic stage. The transgenic non-human mammals can be used as ligand-independent in vivo models for the identification and development of selective tyrosine kinase modulators for the treatment of cancer.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: September 4, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: David K. Bol, Joan M. Carboni, Ronald B. Rowley, Tai W. Wong, Francis Y. Lee
  • Pyrrolotriazine kinase inhibitors
    Patent number: 7173031
    Abstract: In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.
    Type: Grant
    Filed: June 24, 2005
    Date of Patent: February 6, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert M. Borzilleri, Zhong Chen, John T. Hunt, Tram Huynh, Michael A. Poss, Gretchen M. Schroeder, Wayne Vaccaro, Tai W. Wong, Xiao-Tao Chen, Kyoung S. Kim
  • Pyrrolotriazine kinase inhibitors
    Publication number: 20060004006
    Abstract: In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.
    Type: Application
    Filed: June 24, 2005
    Publication date: January 5, 2006
    Inventors: Robert M. Borzilleri, Zhong Chen, John T. Hunt, Tram Huynh, Michael A. Poss, Gretchen M. Schroeder, Wayne Vaccaro, Tai W. Wong, Xiao-Tao Chen, Kyoung KIm
  • Transgenic non-human mammals expressing constitutively activated tyrosine kinase receptors
    Publication number: 20030182668
    Abstract: A transgenic non-human mammal whose germ cells and somatic cells contain a constitutively activated tyrosine kinase receptor introduced into the mammal, or an ancestor of the mammal, at an embryonic stage. The transgenic non-human mammals can be used as ligand-independent in vivo models for the identification and development of selective tyrosine kinase modulators for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 25, 2003
    Inventors: David K. Bol, Joan M. Carboni, Ronald B. Rowley, Tai W. Wong, Francis Y. Lee
  • N.sup..alpha. -Desacetylthymosin.alpha..sub.1 and process
    Patent number: 4293455
    Abstract: The preparation of N.sup..alpha. -desacetylthymosin.alpha..sub.1 and its use as a hormonally active agent participating in the regulation, differentiation and function of thymic dependent lymphocytes (T-cells) is described.
    Type: Grant
    Filed: April 7, 1980
    Date of Patent: October 6, 1981
    Assignee: Rockefeller University
    Inventors: Robert B. Merrifield, Tai W. Wong