Abstract: A method for detecting a dissolution rate of a preparation containing colloidal bismuth pectin includes steps of: according to “Pharmacopoeia of the People's Republic of China, 2010 Edition, Volume 2, Appendix XC”, dispersing the preparation containing the colloidal bismuth pectin into dissolution medium, and directly obtaining dissolution liquid; adding a protonic acid dissociation agent into the dissolution liquid until a hydrogen ion concentration reaches 0.8-1.2 mol/L; centrifuging for separating a supernatant; coloring the supernatant by adding a chromogen solution of citric acid or ascorbic acid and potassium iodide to obtain a test solution; calculating a dissolution amount, which is accounted by bismuth, of the colloidal bismuth pectin with a spectrophotometry method. The method of the present invention well detects dissolution curves and rates of the colloidal bismuth pectin in the preparation thereof, satisfying quality control requirements.

Abstract: Provided is a method for measuring the bismuth content in a colloidal bismuth pectin or a colloidal bismuth pectin-contained preparation. A protonic acid is used to dissociate bismuth from a colloidal bismuth pectin, the principle of the characteristic reaction between bismuth and potassium iodide to produce yellow potassium bismuth iodide is used; ultraviolet-visible spectrophotometry is for measurement; an external standard method is for calculation. The method has strong specificity, a good linear relationship, high accuracy, good repeatability and high sensitivity. The method is able to act as a quality control method for bismuth in a colloidal bismuth pectin or a colloidal bismuth pectin-contained preparation to effectively control the product quality.