Abstract: The EGR cooling structure includes a cylinder block having cylinders, and a cylinder head into which exhaust gas exhausted from the cylinders is collected. An exhaust emission control device is provided for purifying the exhaust gas exhausted from the cylinder head, and an EGR pipe is provided through which EGR gas of a part of the purified exhaust gas is introduced into an intake system. An EGR cooler is provided in the EGR pipe and cools the EGR gas with the cooling liquid. An exhaust gas passage leading from the cylinders to the exhaust gas purification device is curved when seen from a side, and the EGR cooler is disposed in the space surrounded by the cylinder block, the cylinder head, and the exhaust gas purification device.

Abstract: An EGR cooling structure is provided. The EGR cooling structure (1) comprising: a cylinder block (11) having cylinders (11a); a cylinder head (12) (exhaust gas manifold section) into which exhaust gas exhausted from the cylinders (11a) is collected; an exhaust emission control device (20) for purifying the exhaust gas exhausted from the cylinder head (12); an EGR pipe (50) through which EGR gas of a part of the purified exhaust gas is introduced into an intake system r intake system from second exhaust gas piping (32) downstream of the exhaust gas purification device (20); and an EGR cooler (60) provided in the EGR pipe (50) and cooling the EGR gas with the cooling liquid. An exhaust gas passage leading from the cylinders (11a) to the exhaust gas purification device (20) is curved when seen from a side, and the EGR cooler (60) is disposed in the space (5) surrounded by the cylinder block (11), the cylinder head (12), and the exhaust gas purification device (20).

Abstract: In a variable stroke engine assembly for a front engine, front wheel drive vehicle, an engine output shaft (OS), a variable stroke control mechanism (63, 65, CR), an actuator (AC) and a starter motor (SM) are laid out in a favorable manner so that the general outer profile of the engine assembly can be made free from excessive protrusions, an increase in the engine room space requirement is avoided, layout freedom can be enhanced, and the cooling performance for the actuator can be improved.

Abstract: In a variable stroke engine comprising a plurality of links (60, 61) connecting a piston (11) with a crankshaft (30), a control member (65) disposed on an engine main body so as to be moveable in two directions over a prescribed range relative to the engine main body, a control link (63) connecting one of the plurality of links with the control member and an actuator (AC) for displacing the control member, the actuator comprises a ratchet mechanism that utilizes a force transmitted from the piston to the control member as an actuating force for the control member. By providing a spring member (73, SP, 121) that applies a biasing force to the control member, an appropriate actuating force can be applied to the control member in either direction.

Abstract: A variable stroke characteristic engine is provided in which a piston (11) and a crankshaft (30) are linked to a control shaft (65) via a variable stroke link mechanism (LV), and the variable stroke link mechanism (LV) is operated by an actuator (AC) that drives the control shaft (65) to thus make the stroke travel of the piston (11) variable, wherein a housing (HU) of the hydraulic actuator (AC) for operating the variable stroke link mechanism (LV) is provided in a bearing member (54) of a lower block (41) supporting the crankshaft (30), and the housing (HU) is thus made small, thereby suppressing any increase in the dimensions of the engine. Furthermore, a hydraulic switching valve unit (92) for controlling operation of the hydraulic actuator (AC) is directly mounted on the housing (HU), thereby enhancing the responsiveness of the hydraulic actuator (AC).

Abstract: A variable stroke characteristic engine in which a piston (11) and a crankshaft (30) are linked to a control shaft (65) via a variable stroke link mechanism (LV), and the variable stroke link mechanism (LV) is operated by a hydraulic actuator (AC) that drives the control shaft (65) to thus make the stroke travel of the piston (11) variable, in which the hydraulic actuator (AC) is formed from a housing (HU), a cover member covering an aperture of the housing (HU), a vane case provided integrally within the housing (HU), and a vane shaft (66) housed within the vane case, and the vane shaft (66) is formed integrally with the control shaft (65). The number of components of the actuator (AC) can be decreased, and its ease of assembly can be improved.

Abstract: A variable stroke characteristic engine is provided in which a piston (11) and a crankshaft (30) are linked to a control shaft (65) via a variable stroke link mechanism (LV), and the variable stroke link mechanism (LV) is operated by an actuator (AC) that drives the control shaft (65) to thus make the stroke travel of the piston (11) variable, wherein a housing (HU) of the hydraulic actuator (AC) for operating the variable stroke link mechanism (LV) is provided in a bearing member (54) of a lower block (41) supporting the crankshaft (30), and the housing (HU) is thus made small, thereby suppressing any increase in the dimensions of the engine. Furthermore, a hydraulic switching valve unit (92) for controlling operation of the hydraulic actuator (AC) is directly mounted on the housing (HU), thereby enhancing the responsiveness of the hydraulic actuator (AC).

Abstract: In a variable stroke engine assembly for a front engine, front wheel drive vehicle, an engine output shaft (OS), a variable stroke control mechanism (63, 65, CR), an actuator (AC) and a starter motor (SM) are laid out in a favorable manner so that the general outer profile of the engine assembly can be made free from excessive protrusions, an increase in the engine room space requirement is avoided, layout freedom can be enhanced, and the cooling performance for the actuator can be improved.

Abstract: In a variable stroke engine comprising a plurality of links (60, 61) connecting a piston (11) with a crankshaft (30), a control member (65) disposed on an engine main body so as to be moveable in two directions over a prescribed range relative to the engine main body, a control link (63) connecting one of the plurality of links with the control member and an actuator (AC) for displacing the control member, the actuator comprises a ratchet mechanism that utilizes a force transmitted from the piston to the control member as an actuating force for the control member. By providing a spring member (73, SP, 121) that applies a biasing force to the control member, an appropriate actuating force can be applied to the control member in either direction.

Abstract: Crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out by adding water to a solution or suspension comprising paroxetine hydrochloride and a polar organic solvent which contains no water or at most 60% by weight of water to adjust the water content to at least 70% by weight when crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out in a water-containing polar organic solvent. Crystals of paroxetine hydrochloride ½-hydrate being not colored in pink can be allowed to separate out in the presence of hydrogen chloride when crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out in water or a water-containing polar organic solvent.

Abstract: In a variable stroke-characteristic engine for a vehicle, a control shaft and a control link are disposed on a front side of a vehicle body with respect to a crankshaft. An actuator for driving the control shaft is disposed on an outer surface of an engine block on the front side of the vehicle body. Thus, the actuator projects as much as possible from a position of the engine block toward the front side of the vehicle body so that traveling wind from ahead of the vehicle is effectively applied to the actuator to enhance the cooling effect. Hence, any temperature increase of the actuator is suppressed. Moreover, the actuator is disposed as far as possible from an exhaust manifold that is heated to a high temperature by the heat of an exhaust gas.

Abstract: In a variable stroke-characteristic engine for a vehicle, a control shaft and a control link are disposed on a front side of a vehicle body with respect to a crankshaft. An actuator for driving the control shaft is disposed on an outer surface of an engine block on the front side of the vehicle body. Thus, the actuator projects as much as possible from a position of the engine block toward the front side of the vehicle body so that traveling wind from ahead of the vehicle is effectively applied to the actuator to enhance the cooling effect. Hence, any temperature increase of the actuator is suppressed. Moreover, the actuator is disposed as far as possible from an exhaust manifold that is heated to a high temperature by the heat of an exhaust gas.

Abstract: Crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out by adding water to a solution or suspension comprising paroxetine hydrochloride and a polar organic solvent which contains no water or at most 60% by weight of water to adjust the water content to at least 70% by weight when crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out in a water-containing polar organic solvent. Crystals of paroxetine hydrochloride ½-hydrate being not colored in pink can be allowed to separate out in the presence of hydrogen chloride when crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out in water or a water-containing polar organic solvent.

Abstract: A process for preparing a paroxetine hydrochloride hydrate, comprising reacting (3S, 4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-[(3,4-methylene-dioxy)phenoxymethyl]piperidine with hydrogen chloride in the presence of water, and allowing crystals to separate out from the resulting reaction mixture in the presence of water.

Abstract: An L-tartrate of a trans-(−)-4-(4-fluorophenyl)-3-hydroxymethylpiperidine compound, represented by the formula (I): 1

Abstract: An L-tartrate of a trans-(−)-4-(4-fluorophenyl)-3-hydroxymethylpiperidine compound, represented by the formula (I): wherein R1 is hydrogen atom, a substituted or unsubstituted, linear or branched alkyl group having 1 to 6 carbon atoms, or an aralkyl group having 7 to 12 carbon atoms. The L-tartrate of trans-(−)-4-(4-fluorophenyl)-3-hydroxymethylpiperidine compound can be suitably used as an intermediate for pharmaceuticals such as paroxetine which is useful, for example, as an antidepressant.