Abstract: An electrophoresis device includes a mounted reference capillary and a focused optical system. A 2D image of light containing autofluorescence and a 2D image of Raman-scattered light are obtained from the separation medium, and pattern data for autofluorescence and Raman-scattered light are obtained from these. An electrophoresis capillary is mounted in the electrophoresis device, pattern data for autofluorescence and Raman-scattered light is obtained in the same way at each of multiple different focal positions of the optical system, and the focal position of the optical system that best matches that of the reference capillary is used as the in-focus position.

Abstract: In a capillary electrophoresis device, detection window sections of a plurality of capillaries are arranged, and a capillary cassette is mounted and used, the capillary cassette having an excitation-side positioning part and a fluorescence-side positioning part so as to hold the detection window section array therebetween. The capillary electrophoresis device includes an excitation optical system unit and a fluorescence-receiving unit having positioning parts positioned to the capillary cassette. The excitation optical system unit includes a rod-like lens array configured to irradiate an excitation light to each detection window section. The fluorescence-receiving unit includes a rod-like lens array configured to receive a fluorescence from each detection window section, and an optical fiber for each rod-like lens configured to guide fluorescence from the rod-like lens to a detector side.

Abstract: In a capillary electrophoresis device, detection window sections of a plurality of capillaries are arranged, and a capillary cassette is mounted and used, the capillary cassette having an excitation-side positioning part and a fluorescence-side positioning part so as to hold the detection window section array therebetween. The capillary electrophoresis device includes an excitation optical system unit and a fluorescence-receiving unit having positioning parts positioned to the capillary cassette. The excitation optical system unit includes a rod-like lens array configured to irradiate an excitation light to each detection window section. The fluorescence-receiving unit includes a rod-like lens array configured to receive a fluorescence from each detection window section, and an optical fiber for each rod-like lens configured to guide fluorescence from the rod-like lens to a detector side.

Abstract: An electrophoresis device includes a mounted reference capillary and a focused optical system. A 2D image of light containing autofluorescence and a 2D image of Raman-scattered light are obtained from the separation medium, and pattern data for autofluorescence and Raman-scattered light are obtained from these. An electrophoresis capillary is mounted in the electrophoresis device, pattern data for autofluorescence and Raman-scattered light is obtained in the same way at each of multiple different focal positions of the optical system, and the focal position of the optical system that best matches that of the reference capillary is used as the in-focus position.

Abstract: A pump is used to draw in a sample into a sample suction tube, and the sample is introduced into a capillary tube that is disposed straight in the horizontal direction. Because the sample is drawn in through the sample suction tube in this way, there is no need to bend the capillary tube so as to dip an end portion thereof into the sample. The result is that there is no need to lengthen the capillary tube to compensate for the degree of separation that is lost through bending of the capillary tube, and thus the capillary tube may be shorter, enabling the analysis to be performed more quickly and with higher throughput.

Abstract: A microchip processing apparatus processes a microchip with at least one main separation channel. The microchip processing apparatus includes a holding part configured to hold the microchip, a container containing a sample or a reagent, and a dispensing probe having a needle formed on a tip of the dispensing probe. The dispensing probe is actuated to be inserted into the container from above the container, to draw the sample or reagent, and to inject to a prescribed position on the held microchip. A dispensing probe driving mechanism moves the dispensing probe between prescribed positions of the microchip and the container.

Abstract: A microchip processing apparatus processes a microchip with at least one main separation channel. The microchip processing apparatus includes a holding part configured to hold the microchip, a container containing a sample or a reagent, and a dispensing probe having a needle formed on a tip of the dispensing probe. The dispensing probe is actuated to be inserted into the container from above the container, to draw the sample or reagent, and to inject to a prescribed position on the held microchip. A dispensing probe driving mechanism moves the dispensing probe between prescribed positions of the microchip and the container.

Abstract: The method of measuring the number of molecules or the molecular density of a sample according to the present invention includes the steps of: a) labeling each of the molecules with a preset number of fluorescent substances before or after the sample is fixed on the substrate surface, b) obtaining an image of the fluorescent substances from the whole of the substrate surface or from a part of the substrate surface, c) measuring the number of the fluorescent spots and the intensity of every fluorescent spot, and d) calculate the number of molecules or the density (concentration) of molecules of the sample based on the above-described measurement results.