Patents by Inventor Tai Hyun Park

Tai Hyun Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230027819
    Abstract: The present invention relates to a cell-penetrating peptide dimer comprising: a first peptide domain consisting of the amino acid sequence of SEQ ID NO: 1; a second 30Kc19? peptide domain consisting of the amino acid sequence of SEQ ID NO: 1; and a peptide linker connecting the first and second peptide domains, a method for preparing the peptide dimer, a cargo delivery system in which a cargo is conjugated to the dimer; and a use thereof. The cell-penetrating peptide dimer according to the present invention may have excellent cell-penetrating properties, thereby being usefully employed as the cargo delivery system.
    Type: Application
    Filed: August 31, 2022
    Publication date: January 26, 2023
    Inventors: Tai Hyun PARK, Haein LEE, Yeong Kyu PARK, SooHee RYU, Seong Hoon KIM, Hyeong Seok LEE
  • Publication number: 20220065810
    Abstract: The present invention relates to a graphene channel member comprising a graphene film and a cadaverine olfactory receptor immobilized to the graphene film, a graphene transistor comprising: a substrate; the graphene channel member; and a pair of electrodes, and a bio sensor comprising same.
    Type: Application
    Filed: December 26, 2019
    Publication date: March 3, 2022
    Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Oh Seok KWON, Hyun Seok SONG, Tai Hyun PARK, Kyung Ho KIM, Jin Yeong KIM, Dong Seok MOON, Seon Joo PARK, Chul Soon PARK
  • Publication number: 20210300977
    Abstract: The present invention relates to a cell-penetrating peptide dimer comprising: a first peptide domain consisting of the amino acid sequence of SEQ ID NO: 1; a second 30Kc19a peptide domain consisting of the amino acid sequence of SEQ ID NO: 1; and a peptide linker connecting the first and second peptide domains, a method for preparing the peptide dimer, a cargo delivery system in which a cargo is conjugated to the dimer; and a use thereof. The cell-penetrating peptide dimer according to the present invention may have excellent cell-penetrating properties, thereby being usefully employed as the cargo delivery system.
    Type: Application
    Filed: April 30, 2021
    Publication date: September 30, 2021
    Inventors: Tai Hyun PARK, Haein LEE, Yeong Kyu PARK, SooHee RYU, Seong Hoon KIM, Hyeong Seok LEE
  • Publication number: 20210214401
    Abstract: The present invention relates to a manufacturing method of a nanodisc comprising an olfactory receptor protein, and a nanodisc comprising an olfactory receptor protein manufactured by the same, and more specifically, a manufacturing method of a nanodisc comprising an olfactory receptor protein using E. coli, and a nanodisc comprising an olfactory receptor protein manufactured by the same. According to the present invention, nanodiscs (T13NDs) are manufactured by producing receptors used in T13NDs from E. coli, thereby being able to mimic the original receptor structure and can be stable in water and atmospheric environments, and by the same, not only selectivity, accuracy, and reproducibility can be improved, but also it was possible to selectively detect cadaverine, which is known to occur from rotten foods, through the improved performance ability.
    Type: Application
    Filed: October 30, 2018
    Publication date: July 15, 2021
    Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Tai Hyun Park, Heehong Yang
  • Patent number: 10914736
    Abstract: The present invention relates to a nanovesicle comprising a heterodimeric G-protein coupled receptor, a method for preparing the nanovesicle, a field effect transistor-based taste sensor comprising the nanovesicle, and a method for manufacturing the taste sensor. The field effect transistor based taste sensor functionalized by the nanovesicle comprising the heterodimer G-protein coupled receptor according to the present invention has excellent sensitivity and selectivity and may highly specifically detect a sweet taste substance in real time, by using the heterodimeric G-protein coupled receptor and the nanovesicle comprising the same.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: February 9, 2021
    Assignee: Seoul National University R&DB Foundation
    Inventors: Tai Hyun Park, Seung Hun Hong, Hyun Seok Song, Hye Jun Jin, Sae Ryun Ahn
  • Publication number: 20200271644
    Abstract: The present invention relates to a nanovesicle comprising a heterodimeric G-protein coupled receptor, a method for preparing the nanovesicle, a field effect transistor-based taste sensor comprising the nanovesicle, and a method for manufacturing the taste sensor. The field effect transistor based taste sensor functionalized by the nanovesicle comprising the heterodimer G-protein coupled receptor according to the present invention has excellent sensitivity and selectivity and may highly specifically detect a sweet taste substance in real time, by using the heterodimeric G-protein coupled receptor and the nanovesicle comprising the same.
    Type: Application
    Filed: April 3, 2020
    Publication date: August 27, 2020
    Inventors: Tai Hyun Park, Seung Hun Hong, Hyun Seok Song, Hye Jun Jin, Sae Ryun Ahn
  • Patent number: 9765295
    Abstract: Provided are a sanal culturing composition and a method for culturing sanal using the same.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: September 19, 2017
    Assignees: SAMSUNG ELECTRONICS CO., LTD., ADVANCED INSTITUTES OF CONVERGENCE TECHNOLOGY (AICT), SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Tai Hyun Park, Hwi Jin Ko, Sang Yeob Jeong, Kwangsup Soh, Minseok Kim, Youngjun Koh, Jaeyoung Kim
  • Publication number: 20160231316
    Abstract: The present invention relates to a nanovesicle comprising a heterodimeric G-protein coupled receptor, a method for preparing the nanovesicle, a field effect transistor-based taste sensor comprising the nanovesicle, and a method for manufacturing the taste sensor. The field effect transistor based taste sensor functionalized by the nanovesicle comprising the heterodimer G-protein coupled receptor according to the present invention has excellent sensitivity and selectivity and may highly specifically detect a sweet taste substance in real time, by using the heterodimeric G-protein coupled receptor and the nanovesicle comprising the same.
    Type: Application
    Filed: September 16, 2013
    Publication date: August 11, 2016
    Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Tai Hyun Park, Seung Hun Hong, Hyun Seok Song, Hye Jun Jin, Sae Ryun An
  • Publication number: 20160115442
    Abstract: Provided are a sanal culturing composition and a method for culturing sanal using the same.
    Type: Application
    Filed: July 10, 2015
    Publication date: April 28, 2016
    Inventors: Tai Hyun Park, Hwi Jin Ko, Sang Yeob Jeong, Kwangsup Soh, Minseok Kim, Youngjun Koh, Jaeyoung Kim
  • Patent number: 8377706
    Abstract: In accordance with an aspect of the present invention, there is provided a transistor including: a substrate; a source electrode and a drain electrode formed being spaced apart from each other on the substrate; a nanostructure electrically contacted with and formed between the source electrode and the drain electrode; and a lipid membrane having an olfactory receptor protein which is formed to cover surfaces of the source electrode, the drain electrode, and the nanostructure. The olfactory receptor-functionalized transistor in accordance with an aspect of the present invention is useful for a bioelectronic nose which can detect odorants highly specifically with femtomolar sensitivity, and may be applied in various fields requiring the rapid detection of specific odorants, for example, anti-bioterrorism, disease diagnostics, and food safety.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: February 19, 2013
    Assignee: Seoul National University Industry Foundation
    Inventors: Seung-Hun Hong, Tai Hyun Park, Tae-Hyun Kim, Sang Hun Lee
  • Publication number: 20110059544
    Abstract: In accordance with an aspect of the present invention, there is provided a transistor including: a substrate; a source electrode and a drain electrode formed being spaced apart from each other on the substrate; a nanostructure electrically contacted with and formed between the source electrode and the drain electrode; and a lipid membrane having an olfactory receptor protein which is formed to cover surfaces of the source electrode, the drain electrode, and the nanostructure. The olfactory receptor-functionalized transistor in accordance with an aspect of the present invention is useful for a bioelectronic nose which can detect odorants highly specifically with femtomolar sensitivity, and may be applied in various fields requiring the rapid detection of specific odorants, for example, anti-bioterrorism, disease diagnostics, and food safety.
    Type: Application
    Filed: May 7, 2009
    Publication date: March 10, 2011
    Inventors: Seung-Hun Hong, Tai Hyun Park, Tae-Hyun Kim, Sang Hun Lee
  • Publication number: 20090142840
    Abstract: The present invention relates to DNAs encoding anti-apoptotic 30K proteins. More particularly, the present invention is directed to 30K protein genes and a recombinant proteins prepared by using novel anti-apoptotic gene obtained from silkworm. The present invention also provides anti-apoptotic health care food, pharmaceutical preparation, additive for cell culture medium, and food supplement.
    Type: Application
    Filed: August 7, 2008
    Publication date: June 4, 2009
    Applicant: HANSON BIOTECH CO., LTD.
    Inventors: Tai Hyun Park, Eun Jeong Kim, Hye Jung Park