Patents by Inventor Taiki Shibata
Taiki Shibata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11382870Abstract: The present invention provides a risperidone-containing patch having an excellent drug release property and patch physical properties. Specifically, the present invention provides a medical patch comprising an adhesive composition comprising risperidone or a pharmaceutically acceptable salt thereof; a carboxylic acid; a fatty acid ester; and an adhesive, characterized in that said adhesive is a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a sulfur residue of a mercapto group situated at the center, wherein the (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.99% by mass of the whole structural units in said star-shaped acrylic block polymer, and at least one of said chain polymer portions has a structural unit having a copolymer structure of polymerizable monomers comprising a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a polyfunctional monomer.Type: GrantFiled: April 4, 2018Date of Patent: July 12, 2022Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi Kawakami, Manabu Sogabe, Taiki Shibata, Hiroaki Hasegawa
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Patent number: 11077069Abstract: The present invention provides a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a mercapto group situated at the center, wherein (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.9% by mass of whole structural units of the star-shaped acrylic block polymer, and at least one of the chain polymer portions has a copolymer structure of polymerizable monomers containing a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a weakly basic monomer; and a medical patch containing an adhesive composition containing a salt of a basic drug and the star-shaped acrylic block polymer as an adhesive that exhibits high drug efficacy, that does not cause a decrease in adhesive property of an adhesive base due to an additive, and that causes less skin irritation.Type: GrantFiled: September 30, 2016Date of Patent: August 3, 2021Assignees: TEIKOKU SEIYAKU CO., LTD, NIPPON SHOKUBAI CO., LTD.Inventors: Satoshi Kawakami, Manabu Sogabe, Taiki Shibata, Yasushi Horikawa, Hiroaki Hasegawa
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Publication number: 20210085633Abstract: The purpose of the present invention is to provide a rivastigmine-containing transdermal absorption preparation having high adhesion to the skin and capable of continuously administering rivastigmine over a long period of time. A transdermal absorption preparation has rivastigmine, a rubber polymer, a tackifier resin, and a polymer compound having a nitrogen-containing group.Type: ApplicationFiled: July 12, 2018Publication date: March 25, 2021Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA
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Publication number: 20200108024Abstract: The present invention provides a risperidone-containing patch having an excellent drug release property and patch physical properties. Specifically, the present invention provides a medical patch comprising an adhesive composition comprising risperidone or a pharmaceutically acceptable salt thereof; a carboxylic acid; a fatty acid ester; and an adhesive, characterized in that said adhesive is a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a sulfur residue of a mercapto group situated at the center, wherein the (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.99% by mass of the whole structural units in said star-shaped acrylic block polymer, and at least one of said chain polymer portions has a structural unit having a copolymer structure of polymerizable monomers comprising a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a polyfunctional monomer.Type: ApplicationFiled: April 4, 2018Publication date: April 9, 2020Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA, Hiroaki HASEGAWA
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Patent number: 10335389Abstract: The present invention provides a patch containing beraprost or a pharmacologically acceptable salt thereof, which achieves high transdermal absorption of beraprost or a pharmacologically acceptable salt thereof and has excellent formulation properties.Type: GrantFiled: August 7, 2014Date of Patent: July 2, 2019Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi Kawakami, Manabu Sogabe, Taiki Shibata
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Patent number: 10195162Abstract: The present invention provides a tolterodine-containing patch in which an adhesive layer is laminated on a backing, characterized in that the adhesive layer is obtainable by adding tolterodine to an adhesive base comprising a rubber adhesive, a tackifier resin, and a softener, wherein the tolterodine is present in the form of a free base in the adhesive base.Type: GrantFiled: December 25, 2012Date of Patent: February 5, 2019Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Taiki Shibata, Kensuke Murata, Kenichi Hattori, Shinji Tanaka
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Patent number: 10137098Abstract: Provided is a novel transdermal absorption preparation containing silodosin or tamsulosin, or salt thereof as an active ingredient, wherein the transdermal absorption preparation is capable of keeping a dissolved state for a long time, as well as has a high permeability to a skin, and can effectively and sustainably exert the transdermal absorbability. A transdermal absorption preparation containing the transdermal absorption preparation comprises an acrylic pressure-sensitive adhesive that comprises a copolymer of at least one (meth)acrylic acid monomer and at least one vinyl monomer and that contains a carboxyl group, and at least one transdermal absorption promoting agent selected from the group consisting of oleyl alcohol, lauryl alcohol, and lauromacrogol.Type: GrantFiled: May 20, 2015Date of Patent: November 27, 2018Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi Kawakami, Taiki Shibata, Manabu Sogabe
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Publication number: 20180280315Abstract: The present invention provides a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a mercapto group situated at the center, wherein (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.9% by mass of whole structural units of the star-shaped acrylic block polymer, and at least one of the chain polymer portions has a copolymer structure of polymerizable monomers containing a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a weakly basic monomer; and a medical patch containing an adhesive composition containing a salt of a basic drug and the star-shaped acrylic block polymer as an adhesive that exhibits high drug efficacy, that does not cause a decrease in adhesive property of an adhesive base due to an additive, and that causes less skin irritation.Type: ApplicationFiled: September 30, 2016Publication date: October 4, 2018Applicants: TEIKOKU SEIYAKU CO., LTD., NIPPON SHOKUBAI CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA, Yasushi HORIKAWA, Hiroaki HASEGAWA
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Publication number: 20170079940Abstract: Provided is a novel transdermal absorption preparation containing silodosin or tamsulosin, or salt thereof as an active ingredient, wherein the transdermal absorption preparation is capable of keeping a dissolved state for a long time, as well as has a high permeability to a skin, and can effectively and sustainably exert the transdermal absorbability. A transdermal absorption preparation containing the transdermal absorption preparation comprises an acrylic pressure-sensitive adhesive that comprises a copolymer of at least one (meth)acrylic acid monomer and at least one vinyl monomer and that contains a carboxyl group, and at least one transdermal absorption promoting agent selected from the group consisting of oleyl alcohol, lauryl alcohol, and lauromacrogol.Type: ApplicationFiled: May 20, 2015Publication date: March 23, 2017Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Taiki SHIBATA, Manabu SOGABE
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Publication number: 20160193178Abstract: The present invention provides a patch containing beraprost or a pharmacologically acceptable salt thereof, which achieves high transdermal absorption of beraprost or a pharmacologically acceptable salt thereof and has excellent formulation properties.Type: ApplicationFiled: August 7, 2014Publication date: July 7, 2016Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA
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Publication number: 20150017226Abstract: The present invention provides a tolterodine-containing patch in which an adhesive layer is laminated on a backing, characterized in that the adhesive layer is obtainable by adding tolterodine to an adhesive base comprising a rubber adhesive, a tackifier resin, and a softener, wherein the tolterodine is present in the form of a free base in the adhesive base.Type: ApplicationFiled: December 25, 2012Publication date: January 15, 2015Inventors: Taiki Shibata, Kensuke Murata, Kenichi Hattori, Shinji Tanaka
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Patent number: 8657798Abstract: An external patch containing diclofenac hydroxyethylpyrrolidine prepared by laminating an adhesive layer on a backing, wherein said adhesive layer is characterized by comprising 5-50% by weight of styrene•isoprene•styrene block copolymer, 20-50% by weight of a tackifier resin, 5-70% by weight of a softening agent, and 0.5-20% by weight of one or more solubilizers selected from N-methyl-2-pyrrolidone, propylene glycol and dimethyl sulfoxide as essential ingredients, and 0.5-20% by weight of diclofenac hydroxyethylpyrrolidine as an active ingredient. The patch has excellent transdermal absorption, less skin-irritation and excellent stability of the drug.Type: GrantFiled: January 5, 2011Date of Patent: February 25, 2014Assignees: Teikoku Seiyaku Co., Ltd., IBSA Institut Biochimique SAInventors: Taiki Shibata, Yuichiro Mabuchi, Kenichi Hattori, Takashi Kamakura
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Publication number: 20120283671Abstract: An external patch containing diclofenac hydroxyethylpyrrolidine prepared by laminating an adhesive layer on a backing, wherein said adhesive layer is characterized by comprising 5-50% by weight of styrene•isoprene•styrene block copolymer, 20-50% by weight of a tackifier resin, 5-70% by weight of a softening agent, and 0.5-20% by weight of one or more solubilizers selected from N-methyl-2-pyrrolidone, propylene glycol and dimethyl sulfoxide as essential ingredients, and 0.5-20% by weight of diclofenac hydroxyethylpyrrolidine as an active ingredient. The patch has excellent transdermal absorption, less skin-irritation and excellent stability of the drug.Type: ApplicationFiled: January 5, 2011Publication date: November 8, 2012Inventors: Taiki Shibata, Yuichiro Mabuchi, Kenichi Hattori, Takashi Kamakura