Patents by Inventor Taiping Chen

Taiping Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphorylated NF45 Biomarkers, Antibodies And Methods Of Using Same
    Publication number: 20120021432
    Abstract: The present invention relates to isolated phosphorylated NF45 peptides and isolated phosphorylation site-specific antibody or antigen-binding portion thereof that specifically binds a phosphorylated NF45 protein. The present invention also relates to methods of utilizing these antibodies to determine the therapeutic efficacy of a candidate compound and methods for screening for candidate compounds that increase the phosphorylation of NF45 protein in a cell.
    Type: Application
    Filed: April 15, 2011
    Publication date: January 26, 2012
    Applicant: ArQule, Inc.
    Inventors: Yi Yu, Xiubin Gu, Xiaolan Zhao, Carol Waghorne, Thomas C.K. Chan, Taiping Chen
  • DNA cytosine methyltransferase genes, polypeptides and uses thereof
    Patent number: 7368551
    Abstract: De novo DNA cytosine methyltransferase polynucleotides and polypeptides and methods for producing said polypeptides are disclosed. Also disclosed are methods for utilizing de novo DNA cytosine methyltransferase polynucleotides and polypeptides in diagnostic assays, in vitro DNA methylation assays for screening agonists and antagonists, and therapeutic applications such as the treatment of neoplastic disorders.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: May 6, 2008
    Assignee: The General Hospital Corporation
    Inventors: En Li, Masaki Okano, Shaoping Xie, Taiping Chen
  • De novo DNA cytosine methyltransferase genes, polypeptides and uses thereof
    Publication number: 20040234997
    Abstract: De novo DNA cytosine methyltransferase polynucleotides and polypeptides and methods for producing said polypeptides are disclosed. Also disclosed are methods for utilizing de novo DNA cytosine methyltransferase polynucleotides and polypeptides in diagnostic assays, in vitro DNA methylation assays for screening agonists and antagonists, and therapeutic applications such as the treatment of neoplastic disorders.
    Type: Application
    Filed: July 22, 2003
    Publication date: November 25, 2004
    Applicant: The General Hospital Corporation
    Inventors: En Li, Masaki Okano, Shaoping Xie, Taiping Chen