Patents by Inventor Taiping Gao

Taiping Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEREOSPECIFIC SYNTHESIS PROCESS FOR TRETINOIN COMPOUNDS
    Publication number: 20140275617
    Abstract: A stereospecific synthesis process for tretinoin compounds comprises the following steps: using substituted triphenyl phosphine salt and ?-formyl crotonic acid as raw material to carry out WITTIG reaction under the action of alkali; then adjusting the pH of the reaction liquid to 5-10; adding palladium compound or rhodium compound to carry out isomerization directly and obtain tretinoin compounds with desired configuration. The product yield of the process is high and the intermediate product in the reaction dose not need to be separated. The process is easy to operate and can save the production cost and as well is suitable for industrial production.
    Type: Application
    Filed: May 7, 2012
    Publication date: September 18, 2014
    Applicant: CHONGQING HUABANGSHENGKAI PHARM. CO., LTD
    Inventors: Qingjun Deng, Shaohui Wang, Qiang Zhu, Taiping Gao, Yongsheng Li
  • Stereospecific synthesis process for tretinoin compounds
    Patent number: 8835680
    Abstract: A stereospecific synthesis process for tretinoin compounds comprises the following steps: using substituted triphenyl phosphine salt and ?-formyl crotonic acid as raw material to carry out WITTIG reaction under the action of alkali; then adjusting the pH of the reaction liquid to 5-10; adding palladium compound or rhodium compound to carry out isomerization directly and obtain tretinoin compounds with desired configuration. The product yield of the process is high and the intermediate product in the reaction dose not need to be separated. The process is easy to operate and can save the production cost and as well is suitable for industrial production.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: September 16, 2014
    Assignee: Chongqing Huabangshengkai Pharm. Co., Ltd.
    Inventors: Qingjun Deng, Shaohui Wang, Qiang Zhu, Taiping Gao, Yongsheng Li