Patents by Inventor Taisaku Seino
Taisaku Seino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8747744Abstract: An automatic chemical analyzer in which a reaction solution is stirred by air ejected from an air ejection hole placed above a reaction container. The reaction region can be washed and cleaned sufficiently without causing damage, such as exfoliation of a coating reagent. A reaction container disk is provided with a pore and a pressure detector connected with the pore. Before and after the stirring operation, the ejection hole (nozzle) ejecting air is moved and the output value of the pressure detector is compared with a previously measured normal value. With a discharge pipe and a suction pipe inserted to the opening of the reaction container to be close to both ends of the opening and the side wall of the container, the reaction region at the bottom of the container is washed by continuous discharge and suction of cleaning fluid.Type: GrantFiled: January 10, 2013Date of Patent: June 10, 2014Assignee: Hitachi High-Technologies CorporationInventors: Hironobu Yamakawa, Yoichi Aruga, Takenori Okusa, Taisaku Seino
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Publication number: 20120183439Abstract: A chemical analyzer has a reaction vessel magazine 1 having multiple magazine cells 2 having an opening at each of its two ends that houses a reaction vessel 3, and the openings are sealed with protective films 4 and 5. A cutter 9 faces one of the openings of a magazine cell 2 so as to cut the protective film 5 of the magazine cell 2. Also, a pushrod 8 is provided in such a way as to face the other opening of the magazine cell 2 so as to push out the reaction vessel 3 placed inside the cell 2 through the other opening of the cell 2 that the cutter 9 faces. Thus, during removal of the reaction vessel 3 from the magazine cell 2, the antibody or antigen layer on the reaction vessel 3 can be prevented from being damaged.Type: ApplicationFiled: August 10, 2010Publication date: July 19, 2012Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Taisaku Seino, Takenori Okusa
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Publication number: 20120107180Abstract: An automatic chemical analyzer in which a reaction solution is stirred by air ejected from an air ejection hole placed above a reaction container. The reaction region can be washed and cleaned sufficiently without causing damage, such as exfoliation of a coating reagent. A reaction container disk 161 is provided with a pore 240 and a pressure detector 241 connected with the pore. Before and after the stirring operation, the ejection hole (nozzle) 170 ejecting air is moved and the output value of the pressure detector is compared with a previously measured normal value. With a discharge pipe 1101 and a suction pipe 1102 inserted to the opening of the reaction container 1140 to be close to both ends of the opening and the side wall of the container, the reaction region 1150 at the bottom of the container is washed by continuous discharge and suction of cleaning fluid.Type: ApplicationFiled: February 22, 2010Publication date: May 3, 2012Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Hironobu Yamakawa, Yoichi Aruga, Takenori Okusa, Kenichi Takahashi, Taisaku Seino
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Patent number: 7678576Abstract: The invention provides a chemical analysis apparatus which easily agitates and warms up. A chemical analysis apparatus has a motor, a retaining disc which can be rotated by the motor, a plurality of inspection cartridges which are arranged on the retaining disc, a punching machine for punching the inspection cartridges, a warming apparatus and a detection apparatus. The inspection cartridge includes a container formed by a concave portion and a base plate having a flow path. A cover covering the container and the flow path is installed to the base plate. A liquid solution is moved to the container in an outer peripheral side with respect to a rotation axis from the container in an inner peripheral side with respect to the rotation axis via the flow path, by utilizing a centrifugal force generated on the basis of the rotation of the retaining disc.Type: GrantFiled: December 29, 2005Date of Patent: March 16, 2010Assignee: Hitachi High-Technologies CorporationInventors: Shigeyuki Sasaki, Yoshihiro Nagaoka, Noriyo Nishijima, Naruo Watanabe, Michihiro Saito, Taisaku Seino, Satoshi Takahashi
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Publication number: 20090016931Abstract: A chemical analysis device capable of suppressing deterioration of analysis and test accuracy while avoiding contamination by residual samples or reagents and having no complicated configuration is constructed. A pipetting unit is equipped with a syringe, plunger, and needle unit in which a carrier for capturing nucleic acid and a detection cell is mounted on the needle unit. A pipetting unit drive system is configured so that the pipetting unit is detachable. After the detection cell is removed from the pipetting unit and fixed to a nucleic acid amplification detection unit, a suction/dispensing operation of samples/reagents is performed by the pipetting unit and components to be measured are captured by the carrier. Captured components are measured after being dispensed into the detection cell fixed to the nucleic acid amplification detection unit.Type: ApplicationFiled: July 9, 2008Publication date: January 15, 2009Inventors: Taisaku Seino, Hiroshi Umetsu, Michihiro Saito, Takayuki Kanda, Kumiko Hattori
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Patent number: 7400753Abstract: A fluorescent or luminescence image of at least part of a biological sample is imaged, then a transmission light image of at least part of the biological sample is imaged, and thereafter the fluorescent or luminescence image and the transmission light image are overlaid such that the identical area of the sample is coincided to display. The present invention allows detecting the accurate location of fluorescence or luminescence in a given part of the biological sample.Type: GrantFiled: July 3, 2001Date of Patent: July 15, 2008Assignee: Hitachi, Ltd.Inventors: Taisaku Seino, Satoshi Takahashi, Kenji Yasuda, Yoshitada Oshida
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Patent number: 7309568Abstract: A method and apparatus of stably obtaining fluorescent images of two or more fluorescent samples includes disposing the samples onto compartments defined on a substrate. The compartments are sequentially irradiated with an exciting light where the intensity varies. A value of fluorescence as generated from each of the samples is determined, and a fluorescent image is obtained based on the value of fluorescence.Type: GrantFiled: August 26, 2002Date of Patent: December 18, 2007Assignee: Hitachi, Ltd.Inventors: Yoshitada Oshida, Satoshi Takahashi, Kenji Yasuda, Taisaku Seino
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Patent number: 7217352Abstract: An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members can be provided in a container containing the fluid to divide the surface of the fluid into several sections. The container can be transported at a high speed, and the capillary tips can be immersed in the fluid quickly, thereby preventing resolution degradation caused by a long period of exposure of the capillary tips to air. Throughput of sample analysis can also be improved because it is not necessary to wait until waves disappear before conducting an analysis.Type: GrantFiled: May 28, 2003Date of Patent: May 15, 2007Assignees: Hitachi High-Technologies Corporation, Applera CorporationInventors: Taisaku Seino, Tomoyuki Sakai, Miho Ozawa, Masaya Kojima, Eric S. Nordman
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Publication number: 20060159586Abstract: The invention provides a chemical analysis apparatus which easily agitates and warms up. A chemical analysis apparatus has a motor, a retaining disc which can be rotated by the motor, a plurality of inspection cartridges which are arranged on the retaining disc, a punching machine for punching the inspection cartridges, a warming apparatus and a detection apparatus. The inspection cartridge includes a container formed by a concave portion and a base plate having a flow path. A cover covering the container and the flow path is installed to the base plate. A liquid solution is moved to the container in an outer peripheral side with respect to a rotation axis from the container in an inner peripheral side with respect to the rotation axis via the flow path, by utilizing a centrifugal force generated on the basis of the rotation of the retaining disc.Type: ApplicationFiled: December 29, 2005Publication date: July 20, 2006Inventors: Shigeyuki Sasaki, Yoshihiro Nagaoka, Noriyo Nishijima, Naruo Watanabe, Michihiro Saito, Taisaku Seino, Satoshi Takahashi
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Patent number: 7064813Abstract: Disclosed is an apparatus for measuring a micro area in a specimen in which a reagent necessary for observation and examination of a cell smear specimen or a tissue specimen is dropped to cause a reaction for a measurement and an analysis by way of an image. The apparatus includes: a micro reaction unit that is able to select a specific micro area in the specimen and to subject the specific micro area to a reaction-operation; a unit that measures; records and displays an image of the micro area; and a control unit that controls the measuring, recording, and displaying unit. Reactions can be effected quickly on such specimens as smear cell specimens and tissue slice specimens. The application of the reagent solution can be saved. A comparison between local presence of a gene or anti-body and a cell image can be made quickly and easily.Type: GrantFiled: September 25, 2002Date of Patent: June 20, 2006Assignee: Hitachi High-Technologies CorporationInventors: Satoshi Takahashi, Kenji Yasuda, Yoshitada Oshida, Taisaku Seino
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Publication number: 20060073584Abstract: A chemical analyzing apparatus accommodates therein a structure for retaining a sample and reagents. A detecting mechanism detects the sample after reaction with a reagent. After or during extraction of a biological substance from the sample in the structure, a temperature of a fluid in a space around the structure is controlled to a value which is suitable for enzyme.Type: ApplicationFiled: September 30, 2005Publication date: April 6, 2006Inventors: Shigeyuki Sasaki, Yoshihiro Nagaoka, Hirotoshi Ishimaru, Nobuyuki Maki, Toshiaki Yokobayashi, Michihiro Saito, Taisaku Seino
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Publication number: 20040239916Abstract: A fluorescent or luminescence image of at least part of a biological sample is imaged, then a transmission light image of at least part of the biological sample is imaged, and thereafter the fluorescent or luminescence image and the transmission light image are overlaid such that the identical area of the sample is coincided to display. The present invention allows detecting the accurate location of fluorescence or luminescence in a given part of the biological sample.Type: ApplicationFiled: July 16, 2004Publication date: December 2, 2004Inventors: Taisaku Seino, Satoshi Takahashi, Kenji Yasuda, Yoshitada Oshida
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Patent number: 6760105Abstract: A DNA sample added with a plurality of fluorescent marks is irradiated with excitation lights having a plurality of wavelengths and when fluorescence intensities are detected separately, the excitation light and a position on the sample are relatively changed over a desired area once to thereby detect the plurality of fluorescent marks at high speed.Type: GrantFiled: January 18, 2002Date of Patent: July 6, 2004Assignee: Hitachi, Ltd.Inventors: Yoshitada Oshida, Satoshi Takahashi, Taisaku Seino, Kenji Yasuda
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Publication number: 20030221965Abstract: An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members can be provided in a container containing the fluid to divide the surface of the fluid into several sections. The container can be transported at a high speed, and the capillary tips can be immersed in the fluid quickly, thereby preventing resolution degradation caused by a long period of exposure of the capillary tips to air. Throughput of sample analysis can also be improved because it is not necessary to wait until waves disappear before conducting an analysis.Type: ApplicationFiled: May 28, 2003Publication date: December 4, 2003Inventors: Taisaku Seino, Tomoyuki Sakai, Miho Ozawa, Masaya Kojima, Eric S. Nordman
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Patent number: 6606472Abstract: An image forming device and method utilizing an electrostatic latent image recording medium, developing units reserving different colors for developing images on the recording medium, a dryer for drying the developed images, and an adhesion reinforcer for enhancing adhesion of toner particles including electrostatically pressing dried toner particles against a front surface of the electrostatic latent image recording medium.Type: GrantFiled: August 16, 2001Date of Patent: August 12, 2003Assignee: Hitachi, Ltd.Inventors: Akira Mori, Yukio Yamamoto, Kazumi Takahashi, Shogo Matsumoto, Junichi Matsuno, Taisaku Seino, Toshio Ogiso, Yasushi Kinoshita, Keiji Kamio, Kazutaka Sato
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Publication number: 20030087282Abstract: A wide-dynamic range, high-resistivity and high-speed method of stably obtaining fluorescent images of two or more samples which may includes a fluorescent material, comprising the steps of: disposing each of said samples onto each of two or more compartments which an area on a substrate is split into; sequentially irradiating said compartments with an exciting light wherein each of said compartments is irradiated with said exciting light with the intensity changed; detecting one or more fluorescent lights as generated from each of said samples corresponding to said changed intensity of said exciting light every each of said samples; determining the true value of fluorescence as generated from each of said samples by using information on said one or more fluorescent lights as detected every each of said samples; and obtaining a fluorescent image of each of said samples by using said true value of fluorescence from each of said samples, and an apparatus for carrying out the same are provided.Type: ApplicationFiled: August 26, 2002Publication date: May 8, 2003Applicant: Hitachi, Ltd. Incorporation: JapanInventors: Yoshitada Oshida, Satoshi Takahashi, Kenji Yasuda, Taisaku Seino
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Publication number: 20030081209Abstract: Disclosed is an apparatus for measuring a micro area in a specimen in which a reagent necessary for observation and examination of a cell smear specimen or a tissue specimen is dropped to cause a reaction for a measurement and an analysis by way of an image. The apparatus includes a micro reaction unit that is able to select a specific micro area in the specimen and to subject the specific micro area to a reaction-operation; a unit that measures an image of the micro area and records and displays the image of the micro area; and a control unit that controls the measuring, recording, and displaying unit. Hybridization reaction, immune reaction etc. can be effected quickly on such specimens as smear cell specimens and tissue slice specimens. The application of the reagent solution can be saved. A comparison between local presence of a gene or anti-body and a cell image can be made quickly and easily.Type: ApplicationFiled: September 25, 2002Publication date: May 1, 2003Inventors: Satoshi Takahashi, Kenji Yasuda, Yoshitada Oshida, Taisaku Seino
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Publication number: 20020140933Abstract: A DNA sample added with a plurality of fluorescent marks is irradiated with excitation lights having a plurality of wavelengths and when fluorescence intensities are detected separately, the excitation light and a position on the sample are relatively changed over a desired area once to thereby detect the plurality of fluorescent marks at high speed.Type: ApplicationFiled: January 18, 2002Publication date: October 3, 2002Applicant: Hitachi, Ltd.Inventors: Yoshitada Oshida, Satoshi Takahashi, Taisaku Seino, Kenji Yasuda
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Publication number: 20020114742Abstract: Disclosed is a test chamber capable of performing a stain step without moving the test chamber itself under a microscope. The test chamber for observing and testing a smeared specimen, with cells and a tissue specimen comprises an observation portion (fixing portion) for observing the specimen and reagent storage portions, each storing a different reagent (stain liquid, rinse liquid) for stain from others therein, and sends the reagent to the specimen in response to stimulation from the outside to perform the stain.Type: ApplicationFiled: February 20, 2002Publication date: August 22, 2002Applicant: Hitachi, Ltd.Inventors: Satoshi Takahashi, Taisaku Seino, Kenji Yasuda
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Patent number: 6069641Abstract: An ion flow recording apparatus performs recording making density modulation every pixel. When developing on a fine grain toner is to be performed using a liquid developer for an electrostatic latent image, a developing unit (developing roller) is disposed to face a direction of gravity. Namely, a control valve is provided on a pipe for application of a developer to the developing roller or on a joint portion between the pipe and a developer tank, developing units of different two colors are joined to their developer tank portions, and a rotary shaft is provided on the joint portion to be positioned at a point of symmetry to provide alternate use of the two developing units upon turning them. Therefore, developing for a plurality of colors can be simply performed, and such turning of the developing units enables prevention of the toner from deposition in the liquid developer during developing, thereby making it possible to perform a clear recording.Type: GrantFiled: February 20, 1998Date of Patent: May 30, 2000Assignee: Hitachi, Ltd.Inventors: Junichi Matsuno, Shogo Matsumoto, Taisaku Seino, Yasushi Kinoshita, Akira Mori, Keiji Kamio, Akira Sasaki, Mitsuo Suzuki, Tetsuro Akasaki, Shigetaka Furukawa