Patents by Inventor Taisuke Horimoto

Taisuke Horimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High titer recombinant influenza viruses with enhanced replication in vero cells
    Patent number: 10808229
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and genes from vaccine seed virus isolates which include a HA gene segment with a HA2 sequence encoding a HA2 that confers enhanced growth in cells in culture, such as Vero cells.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: October 20, 2020
    Assignee: Wisconsin Alumni Research Foundation (“WARF”)
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • HIGH TITER RECOMBINANT INFLUENZA VIRUSES FOR VACCINES
    Publication number: 20190048324
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes at least five internal genes from an influenza virus isolate that replicates to high titers in embryonated chicken eggs or MDCK cells.
    Type: Application
    Filed: February 26, 2018
    Publication date: February 14, 2019
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • HIGH TITER RECOMBINANT INFLUENZA VIRUSES WITH ENHANCED REPLICATION IN VERO CELLS
    Publication number: 20180340152
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and genes from vaccine seed virus isolates which include a HA gene segment with a HA2 sequence encoding a HA2 that confers enhanced growth in cells in culture, such as Vero cells.
    Type: Application
    Filed: July 26, 2018
    Publication date: November 29, 2018
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • High titer recombinant influenza viruses with enhanced replication in vero cells
    Patent number: 10059925
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and genes from vaccine seed virus isolates which include a HA gene segment with a HA2 sequence encoding a HA2 that confers enhanced growth in cells in culture, such as Vero cells.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: August 28, 2018
    Assignee: Wisconsin Alumni Research Foundation (WARF)
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • High titer recombinant influenza viruses for vaccines
    Patent number: 9926535
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes at least five internal genes from an influenza virus isolate that replicates to high titers in embryonated chicken eggs or MDCK cells.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: March 27, 2018
    Assignee: Wisconsin Alumni Research Foundation (WARF)
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • HIGH TITER RECOMBINANT INFLUENZA VIRUSES FOR VACCINES
    Publication number: 20160208223
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes at least five internal genes from an influenza virus isolate that replicates to high titers in embryonated chicken eggs or MDCK cells.
    Type: Application
    Filed: January 19, 2016
    Publication date: July 21, 2016
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • High titer recombinant influenza viruses for vaccines
    Patent number: 9254318
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes at least five internal genes from an influenza virus isolate that replicates to high titers in embryonated chicken eggs or MDCK cells.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: February 9, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • HIGH TITER RECOMBINANT INFLUENZA VIRUSES WITH ENHANCED REPLICATION IN VERO CELLS
    Publication number: 20160024479
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and genes from vaccine seed virus isolates which include a HA gene segment with a HA2 sequence encoding a HA2 that confers enhanced growth in cells in culture, such as Vero cells.
    Type: Application
    Filed: August 3, 2015
    Publication date: January 28, 2016
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • High titer recombinant influenza viruses with enhanced replication in vero cells
    Patent number: 9109013
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and genes from vaccine seed virus isolates which include a HA gene segment with a HA2 sequence encoding a HA2 that confers enhanced growth in cells in culture, such as Vero cells.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: August 18, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • HIGH TITER RECOMBINANT INFLUENZA VIRUSES WITH ENHANCED REPLICATION IN VERO CELLS
    Publication number: 20110110978
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and genes from vaccine seed virus isolates which include a HA gene segment with a HA2 sequence encoding a HA2 that confers enhanced growth in cells in culture, such as Vero cells.
    Type: Application
    Filed: October 26, 2010
    Publication date: May 12, 2011
    Applicant: WARF- Wisconsin Alumni Research Foundation
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami
  • High titer recombinant influenza viruses for vaccines
    Publication number: 20070231348
    Abstract: The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes at least five internal genes from an influenza virus isolate that replicates to high titers in embryonated chicken eggs or MDCK cells.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 4, 2007
    Inventors: Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami