Patents by Inventor Taisuke Inagaki

Taisuke Inagaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic lactone compounds and their production process
    Patent number: 6187568
    Abstract: This invention provides a process for producing a macrocyclic lactone compound, which comprises cultivating Actinoplanes sp. FERM BP-3832, in the presence of L-proline, L-hydroxyproline or L-nipecotic acid, and then isolating a macrocylic lactone compound from the fermentation broth. The compounds produced by this process include a compound of the following formula: The present invention also relates to a pharmaceutical composition comprising the same, which is useful as immunosuppressive, antimycotic, antitumor agent or the like.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: February 13, 2001
    Assignee: Pfizer Inc
    Inventors: Hiroyuki Nishida, Yuji Yamauchi, Taisuke Inagaki, Yasuhiro Kojima, Nakao Kojima
  • Macrocyclic lactone compounds and their production process
    Patent number: 6001998
    Abstract: This invention provides a process for producing a macrocyclic lactone compound, which comprises cultivating Actinoplanes sp. FERM BP-3832, in the presence of L-proline, L-hydroxyproline or L-nipecotic acid, and then isolating a macrocyclic lactone compound from the fermentation broth. The compounds produced by this process include a compound of formula (I). The present invention also relates to a pharmaceutical composition comprising the same, which is useful as immunosuppressive, antimycotic, antitumor agent or the like.
    Type: Grant
    Filed: October 27, 1997
    Date of Patent: December 14, 1999
    Assignee: Pfizer Inc
    Inventors: Hiroyuki Nishida, Yuji Yamauchi, Taisuke Inagaki, Yasuhiro Kojima, Nakao Kojima
  • Quinolone compounds for the treatment of disorders caused by helicobacter pylori
    Patent number: 5942619
    Abstract: This invention provides processes for producing quinolone compounds which comprise cultivating Amycoa sp. FERM BP-4785, and then isolating quinolone compounds from the fermentation broth. The compounds produced by these processes include compounds of formula (I) wherein R.sup.1 is H, R.sup.2 is (a) and R.sup.3 is CH.sub.3 ; R.sup.1 is CH.sub.3, R.sup.2 is (a) and R.sup.3 is CH.sub.3 ; or R.sup.1 is CH.sub.3, R.sup.2 is (b) and R.sup.3 is CH.sub.3 ; and the like. The present invention also relates to a pharmaceutical composition comprising the same, which is useful in the treatment of diseases, disorders and adverse conditions caused by Helicobacter pylori and is particularly useful in the treatment of gastroduodenal disorders, diseases and adverse conditions caused thereby.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: August 24, 1999
    Assignee: Pfizer Inc.
    Inventors: Koenraad A. Dekker, Liang H. Huang, Taisuke Inagaki, Nakao Kojima, Yasuhiro Kojima, Yuji Yamauchi
  • Phthalide compounds and their production process
    Patent number: 5861518
    Abstract: This invention provides processes for producing phthalide compounds which comprise cultivating Phanerochaete avelutina FERM BP-4787 and then isolating phthalide compounds from the fermentation broth.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: January 19, 1999
    Inventors: Koenraad A. Dekker, Yuji Yamauchi, Taisuke Inagaki, Shinichi Sakemi, Nakao Kojima
  • Rapamycin producer
    Patent number: 5674732
    Abstract: The present invention provides a novel culture which belongs to Actinoplanes (Actinoplanes sp. FERM BP-3832). This culture is capable of producing rapamycin more than ten times efficiently than the cultures which have been reported (e.g., Streptomyces hygroscopicus ATCC 29253). The present invention provides a process for the production of rapamycin which comprises cultivating Actinoplanes sp. FERM BP-3832 and thereafter isolating rapamycin from the fermentation mixture.
    Type: Grant
    Filed: October 26, 1994
    Date of Patent: October 7, 1997
    Assignee: Pfizer Inc.
    Inventors: Hiroyuki Nishida, Tatsuo Sakakibara, Yuji Yamauchi, Taisuke Inagaki, Yasuhiro Kojima, Nakao Kojima