Abstract: A plurality of cDNAs each having a known different base sequence are labeled with a fluorescent dye (FITC), whereby F-cDNA is prepared. The F-cDNA is disposed at a plurality of predetermined positions on the slide glass of a DNA micro array chip. Cy5-cDNA is prepared by synthesizing cDNA from poly(A)-mRNA in the presence of a fluorescent dye (Cy5). The Cy5-cDNA is placed on the DNA micro array chip and hybridized to the F-cDNA. After hybridization, the DNA micro array chip is read by a quantitative apparatus incorporated with an analyzer in which information about the base composition ratio and base length of cDNA has been registered.

Abstract: A radiation image readout apparatus scans an excitation light in a main scanning direction and a sub scanning direction over a stimulable phosphor sheet, on which radiation energy has been stored, and detects the stimulated emission emitted thereupon; wherein, various types of phosphor sheets can be read out at a high resolution and high sensitivity. The excitation light energy level for obtaining an adequate sensitivity for each type of phosphor sheet is obtained. A controller controls the intensity of the excitation light emitted from the light source and the speed of the scanning mechanism, that is, the readout speed, whereby the excitation light projected onto a phosphor sheet of which the diffusion rate has been controlled by the inclusion therein of an navy blue colorant is of a greater energy level than the excitation light projected onto the white stimulable phosphor sheet not containing the navy blue colorant.

Abstract: A stimulable phosphor sheet stored thereon a radiation image is two-dimensionally scanned by a stimulating light beam by projecting the light beam along a main scanning line extending in a main scanning direction and moving one of the stimulable phosphor sheet and the stimulating light beam in a sub-scanning direction relatively to the other so that the stimulable phosphor sheet is exposed to the stimulating light beam along a plurality of main scanning lines arranged in the sub-scanning direction at a predetermined pitch and stimulated emission emitted from the part of the stimulable phosphor sheet exposed to the stimulating light beam is photoelectrically converted to an electric image signal by a photoelectric convertor. The power of the stimulating light beam is controlled depending on the pitch at which the main scanning lines are arranged in the sub-scanning direction.

Abstract: A photomultiplier which detects feeble light emitted by the irradiation of excitation light on an image carrier carrying an image related to a living organism has an integration circuit is DC-coupled with a photomultiplier to convert a current signal output from the photomultiplier, to a voltage signal. The voltage signal converted by the integration circuit is logarithmically compressed with a logarithmic conversion circuit. An offset compensation circuit is provided for reducing an offset voltage that could occur because of charge injection in the integral action of the integration circuit.

Abstract: A plurality of cDNAs each having a known different base sequence are labeled with a fluorescent dye (FITC), whereby F-cDNA is prepared. The F-cDNA is disposed at a plurality of predetermined positions on the slide glass of a DNA micro array chip. Cy5-cDNA is prepared by synthesizing cDNA from poly(A)-mRNA in the presence of a fluorescent dye (Cy5). The Cy5-cDNA is placed on the DNA micro array chip and hybridized to the F-cDNA. After hybridization, the DNA micro array chip is read by a quantitative apparatus incorporated with an analyzer in which information about the base composition ratio and base length of cDNA has been registered.

Abstract: A radiation image readout apparatus scans an excitation light in a main scanning direction and a sub scanning direction over a stimulable phosphor sheet, on which radiation energy has been stored, and detects the stimulated emission emitted thereupon; wherein, various types of phosphor sheets can be read out at a high resolution and high sensitivity. The excitation light energy level for obtaining an adequate sensitivity for each type of phosphor sheet is obtained. A controller controls the intensity of the excitation light emitted from the light source and the speed of the scanning mechanism, that is, the readout speed, whereby the excitation light projected onto a phosphor sheet of which the diffusion rate has been controlled by the inclusion therein of an navy blue colorant is of a greater energy level than the excitation light projected onto the white stimulable phosphor sheet not containing the navy blue colorant.

Abstract: A stimulable phosphor sheet stored thereon a radiation image is two-dimensionally scanned by a stimulating light beam by projecting the light beam along a main scanning line extending in a main scanning direction and moving one of the stimulable phosphor sheet and the stimulating light beam in a sub-scanning direction relatively to the other so that the stimulable phosphor sheet is exposed to the stimulating light beam along a plurality of main scanning lines arranged in the sub-scanning direction at a predetermined pitch and stimulated emission emitted from the part of the stimulable phosphor sheet exposed to the stimulating light beam is photoelectrically converted to an electric image signal by a photoelectric convertor. The power of the stimulating light beam is controlled depending on the pitch at which the main scanning lines are arranged in the sub-scanning direction.

Abstract: A test piece having plural types of probes, an analysis method using the test piece and an analysis system used for the method effectively prevent incorrect association between one set of information concerning detected positions of the probes to which a target substance has bound and the other set of information concerning types and positions of all probes arranged and fixed on the test piece. As management information itself peculiar to the test piece or ID information indicating the content of the management information has been attached to a predetermined location on the test piece, the information concerning the detected positions of the probes to which the target substance has bound may be associated correctly with corresponding management information by detecting the management information or the ID information attached on the test piece concurrently with the positions of the probes to which the target substance has bound.

Abstract: A storage phosphor sheet is conveyed in a conveying direction in which test pieces are conveyed by a conveyor unit, the storage phosphor sheet being continuous in the conveying direction and also being greater in width than the test piece in a direction perpendicular to the conveying direction. The storage phosphor sheet being supplied from a roll of phosphor sheet is superposed by a press roller on the test pieces being conveyed. The storage phosphor sheet is cut by a cutter in order to separate the superposed test piece and storage phosphor sheet from the storage phosphor sheet.

Abstract: An integration circuit is DC-coupled with a photomultiplier to convert a current signal output from the photomultiplier, to a voltage signal. The voltage signal converted by the integration circuit is logarithmically compressed with a logarithmic conversion circuit. An offset compensation circuit is provided for reducing an offset voltage that could occur because of charge injection in the integral action of the integration circuit.

Abstract: The resolution of a stimulable phosphor sheet is improved by applying a magnetic field to the stimulable phosphor sheet in the direction perpendicular to the surface plane thereof, e.g., by using a pair of magnets, while exposing the stimulable phosphor sheet to radiation from radioactive isotopes. The magnetic field may be applied by using a superconducting coil, instead of using the magnets. An electrical field may also be applied instead of or in addition to the magnetic field. As the travel paths of charged particles are wound and focused, expansion of the size of the beam spots (the areas whereon radiation emitted by the radioactive isotopes has been recorded) is restrained.

Abstract: A plurality of cDNAs each having a known different base sequence are labeled with a fluorescent dye (FITC), whereby F-cDNA is prepared. The F-cDNA is disposed at a plurality of predetermined positions on the slide glass of a DNA micro array chip. Cy5-cDNA is prepared by synthesizing cDNA from poly(A)-mRNA in the presence of a fluorescent dye (Cy5). The Cy5-cDNA is placed on the DNA micro array chip and hybridized to the F-cDNA. After hybridization, the DNA micro array chip is read by a quantitative apparatus incorporated with an analyzer in which information about the base composition ratio and base length of cDNA has been registered.

Abstract: An image reading apparatus includes a first laser stimulating ray source for emitting a laser beam having a wavelength of 633 nm or 635 nm, a second laser stimulating ray source for emitting a laser beam having a wavelength of 470 to 480 nm, a laser beam scanning device for scanning the laser beam, at least one light detector for photoelectrically detecting light released from an image carrier carrying an image, and at least one filter member disposed in front of the light detector and having a plurality of filters for transmitting light of different wavelengths. The thus constituted image reading apparatus can be used for a radiation diagnosis system, an autoradiographic system, an electron microscope detecting system and a radiation diffraction image detecting system using a stimulable phosphor and a fluorescence detecting system and an image can be read with high sensitivity.

Abstract: A surface plasmon sensor comprises a prism, a metal film, which is formed on one surface of the prism and is brought into contact with a sample, and a light source for producing a light beam. An optical system causes the light beam to pass through the prism and to impinge upon an interface between the prism and the metal film such that various different angles of incidence may be obtained with respect to the interface. A photodetector detects an intensity of the light beam, which has been totally reflected from the interface, with respect to each of the various different angles of incidence. An electrode stands facing the metal film with a liquid sample intervening therebetween, and a DC voltage is applied across the electrode and the metal film. A substance contained in the liquid sample is thus analyzed quickly and with a high sensitivity.

Abstract: A surface plasmon sensor comprises a prism, a metal film, which is formed on one surface of the prism and is brought into contact with a sample, and a light source for producing a light beam. An optical system causes the light beam to pass through the prism and to impinge upon an interface between the prism and the metal film such that various different angles of incidence may be obtained with respect to the interface. A photodetector detects an intensity of the light beam, which has been totally reflected from the interface, with respect to each of the various different angles of incidence. An electrode stands facing the metal film with a liquid sample intervening therebetween, and a DC voltage is applied across the electrode and the metal film. A substance contained in the liquid sample is thus analyzed quickly and with a high sensitivity.

Abstract: A surface plasmon sensor comprises a prism, a metal film, which is formed on one surface of the prism and is brought into contact with a sample, and a light source for producing a light beam. An optical system causes the light beam to pass through the prism and to impinge upon an interface between the prism and the metal film such that various different angles of incidence may be obtained with respect to the interface. A photodetector detects an intensity of the light beam, which has been totally reflected from the interface, with respect to each of the various different angles of incidence. An electrode stands facing the metal film with a liquid sample intervening therebetween, and a DC voltage is applied across the electrode and the metal film. A substance contained in the liquid sample is thus analyzed quickly and with a high sensitivity.

Abstract: A surface plasmon sensor comprises a prism, a metal film, which is formed on one surface of the prism and is brought into contact with a sample, and a light source for producing a light beam. An optical system causes the light beam to pass through the prism and to impinge upon an interface between the prism and the metal film such that various different angles of incidence may be obtained with respect to the interface. A photodetector detects an intensity of the light beam, which has been totally reflected from the interface, with respect to each of the various different angles of incidence. An electrode stands facing the metal film with a liquid sample intervening therebetween, and a DC voltage is applied across the electrode and the metal film. A substance contained in the liquid sample is thus analyzed quickly and with a high sensitivity.

Abstract: A chemiluminescent detecting method includes the steps of uniformly irradiating with radiation a stimulable phosphor sheet formed with a stimulable phosphor layer containing a stimulable phosphor which can store an energy of radiation and be stimulated by visible light to emit the energy of radiation in a form of light, thereby storing energy of radiation uniformly therein, selectively labeling a biopolymer with a labeling substance which can produce chemiluminescent light by contact of itself and a chemiluminescent substance, causing the biopolymer labeled with the labeling substance and the chemiluminescent substance to come into contact with each other, and exposing the stimulable phosphor sheet to chemiluminescent light produced by the contact of the biopolymer labeled with the labeling substance and the chemiluminescent substance.

Abstract: A video image storage device comprises a signal input means capable of analog-to-digital conversion of input video signals including various types of scanning lines such as different numbers of scanning lines, a frame memory means capable of memorizing image signals and signal output means. The video image storage device further comprises an input signal generating means, an output signal generating means and a frame memory control means. The input signal generating means comprises a N multiplying circuit capable of N multiplying horizontal synchronizing pulses. The number of N in a dividing circuit can be arbitarily determined by the relation between effective image period and blanking period, and thus the video image storage device can store input video signals having different scanning line numbers which depend upon the types of diagnostic modalities.

Abstract: A CRT image recording apparatus in which a picture a CRT image displayed on a CRT is photographed by a camera. In this apparatus, the number of vertical synchronizing signals separated from a video signal is counted, and the exposure time during which the CRT image is photographed is determined so as to correspond to the number of vertical synchronizing signals 2.sup.K .multidot.n (where K and n are integers) thereby counted. The exposure time is therefore determined is synchronism with the vertical synchronizing signals, thereby preventing any nonuniformity of exposure from occurring on a film.