Patents by Inventor Tajesh PATEL

Tajesh PATEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPIROCYCLIC PIPERIDINYL DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF
    Publication number: 20250115572
    Abstract: Provided herein are compounds of formula (I) and pharmaceutical compositions thereof useful for treating diseases or disorders mediated by the complement factor B. (I).
    Type: Application
    Filed: January 20, 2023
    Publication date: April 10, 2025
    Inventors: Christopher M. ADAMS, Lara C. CZABANIUK, Stefanie FLOHR, François GESSIER, Michael Christoph HEDIGER, Konstanze HURTH, Nancy LABBE-GIGUERE, Fabio LIMA, Tajesh PATEL, Oliver SIMIC, Martin SENDZIK, Angela VITREY, Anna VULPETTI
  • HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF
    Publication number: 20250092042
    Abstract: The present invention provides a method for manufacturing a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R1 R2, R4 and X1 are defined herein.
    Type: Application
    Filed: October 23, 2024
    Publication date: March 20, 2025
    Inventors: Mallesh BUSHABOINA, Xin CHEN, Atwood Kim CHEUNG, Andrew James CULSHAW, Timothy Brian HURLEY, Nancy LABBE-GIGUERE, Wolfgang MILTZ, David ORAIN, Tajesh PATEL, Srinivasan RAJAGOPALAN, Till ROEHN, David Andrew SANDHAM, Gebhard THOMA, Ritesh Bhanudasji TICHKULE, Rudolf WÄLCHLI
  • SODIUM CHANNEL BLOCKERS
    Publication number: 20250034108
    Abstract: The present disclosure relates to sulfonamide compounds, the use thereof for modulating the sodium channel Nav1.5 and methods of treating or preventing diseases, disorders, or conditions using the same.
    Type: Application
    Filed: July 5, 2024
    Publication date: January 30, 2025
    Inventors: Robert Francis DAY, Hatice Belgin GULGEZE EFTHYMIOU, Adam FRIEDMAN, Tyler HARRISON, Jay Francis LARROW, Yunshan PENG, Nichola SMITH, Haihao TANG, Yanxiang WU, Sandra Marie KING, Sii Hong LAU, Tajesh PATEL
  • Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof
    Patent number: 12157737
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R1 R2, R4 and X1 are defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: May 18, 2023
    Date of Patent: December 3, 2024
    Assignee: Novartis AG
    Inventors: Mallesh Bushaboina, Xin Chen, Atwood Kim Cheung, Andrew James Culshaw, Timothy Brian Hurley, Nancy Labbe-Giguere, Wolfgang Miltz, David Orain, Tajesh Patel, Srinivasan Rajagopalan, Till Roehn, David Andrew Sandham, Gebhard Thoma, Ritesh Bhanudasji Tichkule, Rudolf Wälchli
  • HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF
    Publication number: 20240043425
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R1 R2, R4 and X1 are defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: May 18, 2023
    Publication date: February 8, 2024
    Inventors: Mallesh BUSHABOINA, Xin CHEN, Atwood Kim CHEUNG, Andrew James CULSHAW, Timothy Brian HURLEY, Nancy LABBE-GIGUERE, Wolfgang MILTZ, David ORAIN, Tajesh PATEL, Srinivasan RAJAGOPALAN, Till ROEHN, David Andrew SANDHAM, Gebhard THOMA, Ritesh Bhanudasji TICHKULE, Rudolf WÄLCHLI
  • Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof
    Patent number: 11708366
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R1 R2, R4 and X1 are defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: August 12, 2021
    Date of Patent: July 25, 2023
    Assignee: Novartis AG
    Inventors: Mallesh Bushaboina, Xin Chen, Atwood Kim Cheung, Andrew James Culshaw, Timothy Brian Hurley, Nancy Labbe-Giguere, Wolfgang Miltz, David Orain, Tajesh Patel, Srinivasan Rajagopalan, Till Roehn, David Andrew Sandham, Gebhard Thoma, Ritesh Bhanudasji Tichkule, Rudolf Wälchli
  • HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF
    Publication number: 20220048909
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R1 R2, R4 and X1 are defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: August 12, 2021
    Publication date: February 17, 2022
    Inventors: Mallesh BUSHABOINA, Xin CHEN, Atwood Kim CHEUNG, Andrew James CULSHAW, Timothy Brian HURLEY, Nancy LABBE-GIGUERE, Wolfgang MILTZ, David ORAIN, Tajesh PATEL, Srinivasan RAJAGOPALAN, Till ROEHN, David Andrew SANDHAM, Gebhard THOMA, Ritesh Bhanudasji TICHKULE, Rudolf WÄLCHLI
  • POLYCYCLIC HERG ACTIVATORS
    Publication number: 20160108025
    Abstract: The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: December 30, 2015
    Publication date: April 21, 2016
    Inventors: Gregory Raymond Bebernitz, Emma Cody, Tajesh Patel, Ming Qian, Lewis Whitehead, Thomas Zabawa, Frederic Zecri
  • Polycyclic HERG activators
    Patent number: 9255093
    Abstract: The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: February 9, 2016
    Assignee: NOVARTIS AG
    Inventors: Gregory Raymond Bebernitz, Emma Cody, Tajesh Patel, Ming Qian, Lewis Whitehead, Thomas Zabawa, Frederic Zecri
  • POLYCYCLIC HERG ACTIVATORS
    Publication number: 20150299181
    Abstract: The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: April 16, 2015
    Publication date: October 22, 2015
    Inventors: Gregory Raymond BEBERNITZ, Emma CODY, Tajesh PATEL, Ming QIAN, Lewis WHITEHEAD, Thomas ZABAWA, Frederic ZECRI