Abstract: Disclosed herein are methods of treating a subject having an autoimmune or inflammatory disease, and formulations associated therewith, comprising administering to the patient a compound of(S)-5-benzyl-N-(7-(3-hydroxy-3-methylbut-1-yn-1-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-3-carboxamide, or a pharmaceutically acceptable salt thereof, wherein the compound or the pharmaceutically acceptable salt is administered at a dose of about 12.5 mg to about 125 mg free base equivalent of said compound per dose.

Abstract: The present invention discloses a multi-zone pressure sensitive mat comprises a first electrode and a second electrode, wherein: the first electrode connects to an input port of a central processing unit and the second electrode connects to the digital ground return port of the central processing unit; the central processing unit comprises at least one MCU, the MCU comprises a first ADC unit and a second ADC unit, wherein electrical signal form the input port is split into original DC signal and its AC signal, wherein the DC signal is fed into the first ADC unit from the input port, the AC signal is bypassed through a capacitor from the input port, filtered through a LPF, amplified through an amplifying circuit and fed into the second ADC unit; wherein a preset threshold voltage level and a preset interval of time are stored in the MCU; the MCU detects the presence, the absence and the movement of human on bed by measuring voltage value from output port of the first ADC unit and amplitude of the AC signal fro

Abstract: The present invention discloses a multi-zone pressure sensitive mat comprises a first electrode and a second electrode, wherein: the first electrode connects to an input port of a central processing unit and the second electrode connects to the digital ground return port of the central processing unit; the central processing unit comprises at least one MCU, the MCU comprises a first ADC unit and a second ADC unit, wherein electrical signal form the input port is split into original DC signal and its AC signal, wherein the DC signal is fed into the first ADC unit from the input port, the AC signal is bypassed through a capacitor from the input port, filtered through a LPF, amplified through an amplifying circuit and fed into the second ADC unit; wherein a preset threshold voltage level and a preset interval of time are stored in the MCU; the MCU detects the presence, the absence and the movement of human on bed by measuring voltage value from output port of the first ADC unit and amplitude of the AC signal fro

Abstract: A system for design and implementation of a project that includes a plurality of design and testing tools directed to phases of the project's lifecycle. The plurality of design and testing tools is usable for physical horizontal and vertical infrastructure and the physical and vertical infrastructure of the project is constructed based upon a project design created and tested from the plurality of design and testing tools.

Abstract: Information identifying a user as having accessed a first network device from an external network connected device is received at an intermediate network connected device from an edge network device. The intermediate network connected device is arranged between the first network device and a second network device. The intermediate network connected device, the first network device and the second network device are within the network and the external network connected device is outside the network. A request to access the second network device is received at the intermediate network connected device from the first network device. It is determined that the user is a source of the request via the first network device based upon the received information. The request from the first network device is evaluated based upon determining the user is the source of the request.

Abstract: Information identifying a user as having accessed a first network device from an external network connected device is received at an intermediate network connected device from an edge network device. The intermediate network connected device is arranged between the first network device and a second network device. The intermediate network connected device, the first network device and the second network device are within the network and the external network connected device is outside the network. A request to access the second network device is received at the intermediate network connected device from the first network device. It is determined that the user is a source of the request via the first network device based upon the received information. The request from the first network device is evaluated based upon determining the user is the source of the request.

Abstract: A composite material for a lithium ion battery anode and a method of producing the same is disclosed, wherein the composite material comprises a porous electrode composite material. Pores with carbon-based material forming at the pore wall are created in situ. The porous electrode composite material provide space to accommodate volumetric changes during battery charging and discharging while the carbon-based material improved the conductivity of the electrode composite material. The method creates pores to have a denser carbon content inside the pores and a wider mouth of the pores to enhance lithium ion distribution.

Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.

Abstract: A composite material for a lithium ion battery anode and a method of producing the same is disclosed, wherein the composite material comprises a porous electrode composite material. Pores with carbon-based material forming at the pore wall are created in situ. The porous electrode composite material provide space to accommodate volumetric changes during battery charging and discharging while the carbon-based material improved the conductivity of the electrode composite material. The method creates pores to have a denser carbon content inside the pores and a wider mouth of the pores to enhance lithium ion distribution.

Abstract: An instant communication system comprising an instant communication server, a plurality of mobile terminals, and a communication network is provided; the instant communication server includes an instant communication server processor and an instant communication server memory electrically connected to the instant communication server processor; each of the mobile terminals includes a terminal central processor, a terminal communication processor, a display unit, a terminal memory, and at least one information storage unit configured for storing a CID (Calling ID); the terminal central processor is electrically connected with the display unit and the terminal communication processor respectively; the terminal communication processor is further electrically connected with the information storage unit to obtain the CID. The following advantageous effect can be achieved: communications using different phone numbers of one mobile terminal can be distinguished from each other.

Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.

Abstract: A cutting tool assembly is provided for removing flash portions and gates from a molded article. The cutting tool assembly includes a holder device including an upper plate, a cylindrical collar, and a bearing disposed between the upper plate and the cylindrical collar to allow movement of the cylindrical collar relative to the upper plate. The cutting tool assembly further includes a cutting member fixedly secured to the cylindrical collar wherein movement of the cylindrical collar relative to the upper plate provides the cutting member with degrees of rotational freedom to float relative to the molded article during trimming of the flash portions and gates.

Abstract: A combination crib is disclosed that includes a cabinet panel, a bottom panel, an end panel, a pair of removable side rails and movable mattress support. The cabinet panel includes a changing table, a latching mechanism and a damper assembly hidden inside. The changing table is detachably engaged with the latching mechanism. The damper assembly connected to the changing table is adapted for damping the movement of the changing table from the open position to the closed position. The mattress support is vertically movable within the periphery formed by the opposing cabinet and end panels and the opposing side rails.

Abstract: The present compositions related to cleaning and disinfecting compositions particularly useful in the treatment of hard surfaces. The compositions are hard surface cleaning and disinfecting compositions which comprise a combination of a quaternary ammonium compound and an acetylenic diol surfactant compound.

Abstract: A cutting tool assembly is provided for removing flash portions and gates from a molded article. The cutting tool assembly includes a holder device including an upper plate, a cylindrical collar, and a bearing disposed between the upper plate and the cylindrical collar to allow movement of the cylindrical collar relative to the upper plate. The cutting tool assembly further includes a cutting member fixedly secured to the cylindrical collar wherein movement of the cylindrical collar relative to the upper plate provides the cutting member with degrees of rotational freedom to float relative to the molded article during trimming of the flash portions and gates.

Abstract: Improved treatment blocks useful in the treatment of lavatory appliances, particularly toilets are provided. The improved treatment blocks are solid block compositions which comprise at least one detersive surfactant, a diester constituent, and one or more further optional constituents, including bleach constituents. The improved treatment blocks provide improved processing and handling characteristics. Methods of producing the solid block composition and treatment blocks therefrom, as well as methods of use are also disclosed.

Abstract: An electronic component including at least one first conductor for operating at a first voltage applied thereto and at least one second conductor for operating at a second voltage applied thereto. The second voltage is smaller than the first voltage and at least a portion of the second conductor is located on at least one side of the first conductor whereby the second conductor acts as a shield to substantially inhibit at least one of magnetic and electric field from passing from the first conductor to a surrounding medium.

Abstract: Hard surface cleaning and disinfecting compositions comprising cationic surfactants having germicidal properties, fluorosurfactant compounds, film-forming polymers and, optionally, detersive surfactants and or organic solvents. The hard surface cleaning and disinfecting compositions provide excellent cleaning and disinfection of hard surfaces.

Abstract: Improved treatment blocks useful in the treatment of lavatory appliances, particularly toilets are provided. The improved treatment blocks are solid block compositions which comprise at least one detersive surfactant, a hydrocarbon solvent constituent, and one or more further optional constituents, including bleach constituents. The improved treatment blocks provide improved processing and handling characteristics. Methods of producing the solid block composition and treatment blocks therefrom, as well as methods of use are also disclosed.