Patents by Inventor Tak Hung

Tak Hung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HPRP4s modifiers of the p53 pathway and methods of use
    Patent number: 7993829
    Abstract: Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: August 9, 2011
    Assignee: Exelixis Inc.
    Inventors: Lori Friedman, Gregory D. Plowman, Tak Hung, Helen Francis-Lang, Danix Li, Roel P. Funke, Michael Costa
  • SPHKS as modifiers of the p53 pathway and methods of use
    Publication number: 20080241131
    Abstract: Human SPHK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SPHK are provided.
    Type: Application
    Filed: April 3, 2008
    Publication date: October 2, 2008
    Applicant: Exelixis Inc.
    Inventors: Lori S. Friedman, Gregory D. Plowman, Michael R. Costa, Danxi Li, Roel P. Funke, Tak Hung
  • HPRP4s Modifiers of the p53 Pathway and Methods of Use
    Publication number: 20070160539
    Abstract: Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
    Type: Application
    Filed: January 26, 2007
    Publication date: July 12, 2007
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Gregory Plowman, Tak Hung, Helen Francis-Lang, Danxi Li, Roel Funke, Michael Costa
  • Sphks as modifiers of the p53 pathway and methods of use
    Publication number: 20060252035
    Abstract: Human SPHK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SPHK are provided.
    Type: Application
    Filed: August 2, 2002
    Publication date: November 9, 2006
    Inventors: Lori Friedman, Gregory Plowman, Michael Costa, Danxi Li, Roel Funke, Tak Hung
  • Rabs as modifiers of the p53 pathway and methods of use
    Publication number: 20060084063
    Abstract: Human RAB genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of RAB are provided.
    Type: Application
    Filed: July 9, 2003
    Publication date: April 20, 2006
    Inventors: Michael Costa, Mark Maxwell, Mark Lackner, Tak Hung, Carol OBrien, Timothy Heuer, Kim Lickteig
  • Modulators of RabGGT and methods of use thereof
    Publication number: 20040142888
    Abstract: The present invention provides methods for inducing apoptosis in a cell, the methods generally involving contacting the cell with an agent that reduces the level and/or activity of RabGGT. The present invention further provides methods for treating a disorder related to unwanted cell proliferation in an individual, the methods generally involving administering to the individual an agent that reduces the level and/or activity of RabGGT. The present invention further provides methods for reducing apoptosis in a cell, the methods generally involving increasing the level and/or activity of RabGGT in the cell. The present invention further provides methods for treating disorders associated with excessive apoptosis. The present invention further provides methods for identifying a cell that is amenable to treatment with the methods of the present invention. The present invention further provides methods for modulating a binding event between RabGGT and a RabGGT interacting protein.
    Type: Application
    Filed: August 7, 2003
    Publication date: July 22, 2004
    Inventors: Veeraswamy Manne, Mark Lynch, Petra B. Ross-MacDonald, Terry Stouch, Naomi Laing, Pamela Carroll, Kevin Fitzgerald, Louis J. Lombardo, Michael R. Costa, Mark E. Maxwell, Rachel M. Kindt, Mark R. Lackner, Tak Hung, Carol L. O'Brian, Hai Guang Zhang, Katherine S. Brown, Jae Moon Lee
  • HPRP4s as modifiers of the p53 pathway and methods of use
    Publication number: 20030027230
    Abstract: Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
    Type: Application
    Filed: August 2, 2002
    Publication date: February 6, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Tak Hung, Helen Francis-Lang, Danxi Li, Roel P. Funke, Michael Costa