Patents by Inventor Takaaki HABUCHI

Takaaki HABUCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACID COMPOUND AND OLIGONUCLEOTIDE
    Publication number: 20200055890
    Abstract: The present invention aims to provide a nucleic acid compound that hardly forms non-Watson-Crick base pairs, and an oligonucleotide containing the nucleic acid compound and showing reduced non-specific binding with nucleic acids other than the target nucleic acid. The nucleic acid compound according to the present invention is characterized in that the 2-position carbonyl group of the pyrimidine base is functionally converted (X1 and X2 are each independently S or Se), and that the 2?-position and the 4?-position are bridged in a particular structure. The oligonucleotide according to the present invention is characterized in that at least one of thymidine and uridine is the nucleic acid compound.
    Type: Application
    Filed: February 20, 2018
    Publication date: February 20, 2020
    Applicant: Osaka University
    Inventors: Satoshi OBIKA, Kosuke ITO, Takaaki HABUCHI, Masahiko HORIBA