Patents by Inventor Takaaki Nishikiori

Takaaki Nishikiori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound having effect of promoting neuron differentiation
    Patent number: 6384063
    Abstract: A novel cystacycline derivative which has an excellent effect of promoting the differentiation of neurons and is useful as a remedy for central nervous system disorders, a remedy for peripheral nerve disorders, etc.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: May 7, 2002
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Seiichi Saito, Masashi Nagai, Tomio Morino, Tsugio Tomiyoshi, Takaaki Nishikiori, Atsushi Kuwahara, Takamichi Sato, Takashi Harada
  • Antibiotics NK374186A, NK374186B, NK374186B3 and NK374186C3, process for producing the same, and use of the same
    Patent number: 5306496
    Abstract: Novel antibiotics NK374186A, NK374186B, NK374186B3 and NK374186C3 having antibacterial, antineoplastic, immunomodulation, and liver regeneration promoting activities are provided.NK374186A, NK374186B, NK374186B3 and NK374186C3 are obtained by culturing NK374186 strain (FERM P-12285) (FERM-BP 3870) belonging to the genus Penicillium. NK374186A is a compound represented by a rational formula of C.sub.34 H.sub.61 N.sub.3 O.sub.12 S.sub.9 and having a molecular weight of M+ 735 (FD-MS m/z); NK374186B is a compound represented by a rational formula of C.sub.34 H.sub.61 N.sub.3 O.sub.9 and having a molecular weight of M+ 655 (FD-MS m/z); NK374186B3 is a compound represented by a rational formula of C.sub.34 H.sub.61 N.sub.3 O.sub.9 and having a molecular weight of M+ 655 (FD-MS m/z); and NK374186C3 is a compound represented by a rational formula of C.sub.32 H.sub.59 N.sub.3 O.sub.7 and having a molecular weight of M+ 597 (FD-MS m/z).
    Type: Grant
    Filed: June 10, 1992
    Date of Patent: April 26, 1994
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Tomio Morino, Masakazu Nishimoto, Mituyuki Nishide, Akira Masuda, Masatoshi Yamada, Eiji Kawano, Takaaki Nishikiori, Seiichi Saito
  • Antibiotic NK86-0279, process for production of the same and application of the same
    Patent number: 5003056
    Abstract: This invention relates to an antibiotic NK86-0279 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
    Type: Grant
    Filed: December 22, 1988
    Date of Patent: March 26, 1991
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Takaaki Nishikiori, Masanori Yamazaki, Seiichi Saito, Nobuyoshi Shimada, Takashi Kurokawa, Kiyonobu Hirose, Takumi Yamshita, Takako Tsuchiya, Takashi Harada
  • Novel antibiotic NK130119
    Patent number: 4994582
    Abstract: This invention relates to an antibiotic NK130119 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
    Type: Grant
    Filed: January 17, 1990
    Date of Patent: February 19, 1991
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Takaaki Nishikiori, Masanori Yamazaki, Seiichi Saito, Nobuyoshi Shimada, Takashi Kurokawa, Kiyonobu Hirose, Takumi Yamashita, Takashi Harada
  • Plipastatin and method for preparation thereof
    Patent number: 4742155
    Abstract: Plipastatin represented by the general formula ##STR1## wherein R.sub.1 is --C.sub.13 H.sub.27 or --C.sub.14 H.sub.29 ; and R.sub.2 is Ala or Val, or salts thereof, which is prepared by culturing a Plipastatin-producing strain belonging to the genus Bacillus to produce and accumulate Plipastatin in a cultured broth and then isolating Plipastatin from the cultured broth. Plipastatin exhibits an enzyme inhibiting activity against phospholipase A.sub.2, C and D and which will be useful as an immunosuppressive agent or as a type I anti-allergic agent.
    Type: Grant
    Filed: November 26, 1985
    Date of Patent: May 3, 1988
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Takaaki Aoyagi, Tomio Takeuchi, Masa Hamada, Hiroshi Naganawa, Yasuhiko Muraoka, Takaaki Nishikiori