Abstract: The vibration and noise generated in a permanent magnet synchronous motor are effectively suppressed. A motor control device 1 comprises: a triangular wave generation unit 17 which generates a triangular wave signal Tr that is a carrier wave, a carrier frequency adjustment unit 16 which adjusts a carrier frequency fc that represents a frequency of the triangular wave signal Tr, and a gate signal generation unit 18 which performs pulse-width modulation on three-phase voltage commands Vu*, Vv*, Vw* according to a torque command T* using the triangular wave signal Tr, thereby generating a gate signal for controlling an operation of an inverter. The carrier frequency adjustment unit 16 adjusts the carrier frequency fc so as to change a voltage phase error ??v representing a phase difference of the three-phase voltage commands Vu*, Vv*, Vw* and the triangular wave signal Tr based on the torque command T*, and a rotation speed ?r of a motor.

Abstract: A pneumatic tire 1 has a bead portion provided with a reinforcing rubber portion disposed adjacently to the axially outer side of a carcass. The reinforcing rubber portion comprises an axially inner rubber layer and an axially outer rubber layer. The radially outer end of the axially outer rubber layer is positioned radially outside the radially outer end of the axially inner rubber layer. The radially inner end of the axially outer rubber layer is positioned radially inside the radially inner end of the axially inner rubber layer.

Abstract: A tire includes, in a tread portion, a pair of shoulder main grooves, a crown region between the shoulder main grooves, and shoulder regions disposed outside of the shoulder main grooves in a tire axial direction. Land ratios of the crown region and the shoulder regions are respectively 40%-60%. In the crown region, a plurality of middle blocks are arranged on both sides of a tire equator, and each middle block has a longitudinal shape in which a length in the tire circumferential direction is larger than a length in the tire axial direction.

Abstract: A tire includes a tread portion provided with lateral grooves extending in a tire axial direction and blocks divided by the lateral grooves. At least one of the lateral grooves is provided with a first projected portion with a bottom protruding from a groove bottom of the at least one of the lateral grooves. The first projected portion includes at least one tie-bar portion connecting a pair of blocks with each other which is arranged adjacently through the at least one of the lateral groove, and a narrow rib-portion extending in a longitudinal direction of the at least one of the lateral groove from the at least one tie-bar portion without being connected to the pair of blocks.

Abstract: A water dispenser which is connected to a pure water source and used for dispensing pure water includes: an arm mounting unit; a water dispensing gun including a nozzle for discharging pure water; a holding unit for holding the water dispensing gun; and at least two arms connecting the holding unit to the arm mounting unit. The at least two arms constitute a parallel link mechanism in which a trajectory of each arm when the at least two arms move is within the same vertical plane.

Abstract: A water dispenser which is connected to a pure water source and used for dispensing pure water includes: an arm mounting unit; a water dispensing gun including a nozzle for discharging pure water; a holding unit for holding the water dispensing gun; and at least two arms connecting the holding unit to the arm mounting unit. The at least two arms constitute a parallel link mechanism in which a trajectory of each arm when the at least two arms move is within the same vertical plane.

Abstract: The objective of the present invention is to provide a capsule filling composition which can stably produce a capsule formulation by suppressing the flow of components out of the capsule body during capsule filling, regardless of the compressibility of an active ingredient such as drugs and health foods, so that a favorable capsule filling can be achieved; and a method of producing a capsule formulation with the use of such a capsule filling composition, as well as a capsule formulation. The objective is achieved by a method of producing a capsule formulation, comprising subjecting a capsule filling composition containing an active ingredient and a cellulose ether powder to a funnel system powder filling or a die-compression system powder filling to obtain the capsule formulation, and the like.

Abstract: There are provided a coating composition for applying inkjet printing thereto to form a marked preparation, the composition providing good ink affinity, suppression of ink bleed, and excellent gloss; and others. More specifically, there are provided a composition for applying inkjet printing thereto to form a marked preparation, the composition including a water-soluble cellulose ether having a viscosity at 20° C. of from 2 to 50.0 mPa·s, as determined in 2% by mass aqueous solution, polyvinyl alcohol, and a solvent, wherein a mass ratio of the water-soluble cellulose ether to the polyvinyl alcohol is from 99.0:1.0 to 55.0:45.0; a method for producing a preparation marked with aqueous ink, including a coating step of coating an object with the composition to form a coating layer, and a printing step of inkjet-printing on the coating layer with aqueous ink to obtain a preparation marked with aqueous ink; and others.

Abstract: A tire includes, in a tread portion, a pair of shoulder main grooves, a crown region between the shoulder main grooves, and shoulder regions disposed outside of the shoulder main grooves in a tire axial direction. Land ratios of the crown region and the shoulder regions are respectively 40%-60%. In the crown region, a plurality of middle blocks are arranged on both sides of a tire equator, and each middle block has a longitudinal shape in which a length in the tire circumferential direction is larger than a length in the tire axial direction.

Abstract: Provided are a solid preparation comprising an enteric solid dispersion that allows a drug in the preparation to be rapidly dissolved without impairing the dissolution of the solid preparation, and a method for producing the same. More specifically, provided are a solid preparation comprising a poorly soluble drug, an enteric polymer, an excipient and a disintegrator, a mixed powder comprising at least the excipient and the disintegrator is partly or entirely covered with a solid dispersion comprising the poorly soluble dug and the enteric polymer; and a method for producing a solid preparation, comprising steps of: spraying an enteric polymer solution in which a poorly soluble drug has been dispersed or dissolved, on a mixed powder comprising an excipient and a disintegrator; and granulating and drying a resultant.

Abstract: An enteric preparation having a film-forming property and acid resistance is provided by using a simple and efficient method without using a special cooling apparatus. More specifically, provided is a method for producing an aqueous enteric coating liquid including the steps of: partially neutralizing an aqueous suspension including a cellulosic enteric material with an aqueous alkali solution, and mixing the partially-neutralized aqueous suspension with a plasticizer. Also provided is a solid preparation including a core including a drug and a coating portion obtained by coating the core with the produced aqueous enteric coating liquid. Further, provided is a method for producing a solid preparation, including respective steps in the method for producing an aqueous enteric coating liquid and a step of coating a core including a drug with the produced aqueous enteric coating liquid.

Abstract: A granule or a tablet of a solid dispersion that allows a drug in a preparation to be rapidly dissolved without impairing dissolving of the solid dispersion, and a method for producing same is composed of 1 to 10% by weight of a poorly soluble drug, a water-soluble polymer, an excipient and 15 to 50% by weight if a disintegrator; a tablet of a solid dispersion composed of a poorly soluble drug, 1 to 5% by weight of a water-soluble polymer, an excipient and 15 to 50% by weight of a disintegrator; and a method for producing a granule or tablet of a solid dispersion comprising spraying a water-soluble polymer solution, in which a poorly soluble drug has been dispersed or dissolved, on a mixed powder of an excipient and a disintegrator, and granulating and drying a resultant.

Abstract: A granule or a tablet of a solid dispersion that allows a drug in a preparation to be rapidly dissolved without impairing dissolving of the solid dispersion, and a method for producing same is composed of 1 to 10% by weight of a poorly soluble drug, a water-soluble polymer, an excipient and 15 to 50% by weight if a disintegrator; a tablet of a solid dispersion composed of a poorly soluble drug, 1 to 5% by weight of a water-soluble polymer, an excipient and 15 to 50% by weight of a disintegrator; and a method for producing a granule or tablet of a solid dispersion comprising spraying a water-soluble polymer solution, in which a poorly soluble drug has been dispersed or dissolved, on a mixed powder of an excipient and a disintegrator, and granulating and drying a resultant.

Abstract: Provided are a granule or a tablet of a solid dispersion that allows a drug in a preparation to be rapidly dissolved without impairing the dissolution of the solid dispersion, and a method for producing the same.

Abstract: Provided are a solid dosage form comprising an enteric solid dispersion that allows a drug in the preparation to be rapidly dissolved without compromising the solubility of the solid dispersion, and a method for producing the same. More specifically, provided is a solid dosage form comprising an enteric solid dispersion comprising a poorly soluble drug, an enteric polymer and a disintegrant, wherein the disintegrant is low-substituted hydroxypropylcellulose having an average particle size of 10 to 100 ?m and a specific surface area measured by BET method of at least 1.0 m2/g. Moreover, provided is a method for producing a solid dosage form comprising an enteric solid dispersion, the method comprising steps of: spraying an enteric polymer solution in which a poorly soluble drug has been dispersed or dissolved, on a powder of low-substituted hydroxypropylcellulose having an average particle size of 10 to 100 ?m and a specific surface area measured by BET method of at least 1.

Abstract: Provided are a solid dosage form comprising a solid dispersion that allows a drug in the preparation to be rapidly dissolved without compromising the solubility of the solid dispersion, and a method for producing the same. More specifically, provided is a solid dosage form comprising a solid dispersion, the dispersion comprising: a poorly soluble drug, a water-soluble polymer and a disintegrant, wherein the disintegrant is low-substituted hydroxypropylcellulose having an average particle size of 10 to 100 ?m and a specific surface area measured by BET method of at least 1.0 m2/g. Moreover, provided is a method for producing a solid dosage form comprising a solid dispersion, the method comprising steps of: spraying a water-soluble polymer solution in which a poorly soluble drug has been dispersed or dissolved, on a powder of low-substituted hydroxypropylcellulose having an average particle size of 10 to 100 ?m and a specific surface area measured by BET method of at least 1.

Abstract: Provided are a coating composition for delayed release preparation capable of releasing a drug promptly in the stomach, without causing a time-dependent change, after a time (lag time) in which a solid preparation does not release the drug; and a solid preparation obtained by coating of the coating composition. More specifically, provided are a coating composition comprising at least a nonionic water-soluble cellulose ether and a cellulose-based enteric base material, wherein a weight ratio of the nonionic water-soluble cellulose ether to the cellulose-based enteric base material is from 95:5 to 65:35; and a solid preparation comprising at least a drug-containing core and the coating composition which covers the core, wherein the preparation can permit prompt dissolution of the drug in a stomach after a lag time.