Patents by Inventor Takafumi Imaizumi

Takafumi Imaizumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180251721
    Abstract: A cell culture module includes a cell culture substrate that has, on a surface thereof, a recessed portion that cultures a cell, in which at least a bottom surface of the recessed portion includes a porous body, a holding member that houses the cell culture substrate and that has an internal space partitioned into a first space and a second space by the cell culture substrate, and an oxygen sensor that is provided inside the first space of the holding member and that measures a concentration of dissolved oxygen in the culture medium. The oxygen sensor measures the concentration of dissolved oxygen in the vicinity of the cultured cell.
    Type: Application
    Filed: March 1, 2018
    Publication date: September 6, 2018
    Inventors: Shinya HASHIMOTO, Takafumi IMAIZUMI, Yukiko KIKUCHI, Kazunobu TSUNEMOTO, Takaaki ITOI, Misao OBASE
  • Publication number: 20170342377
    Abstract: A cell culture carrier includes a first substrate. The first substrate has a plurality of wells on an upper surface and includes a porous body. The porous body has pores with an average pore diameter of 0.05 ?m or more and 10 ?m or less, and has a porosity of 25% or more and 50% or less. The first substrate has a thickness from a lowermost portion of the well to a lower surface of the substrate of 50 ?m or more and 10 mm or less.
    Type: Application
    Filed: May 26, 2017
    Publication date: November 30, 2017
    Inventors: Takafumi IMAIZUMI, Shinya HASHIMOTO
  • Patent number: 9428728
    Abstract: A colony (cell mass) proliferated under the undifferentiated state is obtained by using a carrier for cell culture in which two or more of a concavity having a porous body in a surface are arranged on a substrate surface in the form of a matrix, inoculating an undifferentiated cell on at least one concavity of the carrier for culture and carrying out culture.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: August 30, 2016
    Assignee: COORSTEK KK
    Inventors: Fumihiko Kitagawa, Takafumi Imaizumi, Katsunori Sasaki
  • Patent number: 9096826
    Abstract: A culture substrate made of ceramics of any one or more of titania, alumina, zirconia, yttria, and carbon is used where minute pores having a pore diameter of from 0.1 ?m to 10 ?m are provided at least for a place to which a cell is seeded, and an undifferentiated cell is seeded to at least one place of a surface of the culture substrate, whereby a culture substrate and a culture method for efficiently culturing the undifferentiated cell to be formed into a 3-dimensional cell block shape without causing immune rejection, and an undifferentiated cultured cell.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: August 4, 2015
    Assignee: COVALENT MATERIALS CORPORATION
    Inventors: Fumihiko Kitagawa, Takafumi Imaizumi, Katsunori Sasaki
  • Patent number: 8673638
    Abstract: The present invention relates to a cell culture support for culturing mesenchymal stem cells, which includes en upper surface including a plurality of wells, in which the upper surface has a root mean square roughness Rq of 100 to 280 nm and a linear density of 1.6 to 10 per 1 ?m length.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: March 18, 2014
    Assignee: Covalent Materials Corporation
    Inventors: Fumihiko Kitagawa, Takafumi Imaizumi, Shunsuke Takei, Itsuki Yamamoto, Yasuhiko Tabata
  • Publication number: 20120160766
    Abstract: The present invention relates to a titanium oxide porous particle for blood purification, which includes a titanium oxide, in which when the titanium oxide porous particle is measured by an electron spin resonance measurement at a temperature of 10 K, a signal at a g value of around 1.96 is present, the signal being divided into two signals representing a component g1 parallel to a axis of symmetry and a component g2 vertical to the axis of symmetry, and a signal at a g value of from 2.003 to 2.004 is not substantially present.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 28, 2012
    Applicant: COVALENT MATERIALS CORPORATION
    Inventors: Takafumi IMAIZUMI, Michio Murayama
  • Publication number: 20120034694
    Abstract: The present invention relates to a cell culture support for culturing mesenchymal stem cells, which includes en upper surface including a plurality of wells, in which the upper surface has a root mean square roughness Rq of 100 to 280 nm and a linear density of 1.6 to 10 per 1 ?m length.
    Type: Application
    Filed: August 5, 2011
    Publication date: February 9, 2012
    Applicant: Covalent Materials Corporation
    Inventors: Fumihiko Kitagawa, Takafumi Imaizumi, Shunsuke Takei, Itsuki Yamamoto, Yasuhiko Tabata
  • Publication number: 20100178694
    Abstract: A cell culture module includes a sealing member 10 sealably holding in an inner space 12 a cell culture carrier S made up of a porous body having a concave portion S1 for culturing cells; a water pressure supplying portion 20 supplying a water pressure onto a second surface Sb opposite to a first surface Sa having the concave portion S1 in the state that a culture medium is filled in the inner space 12; and a cell recovering portion 30 recovering from the inner space 12 the cells separated from the concave portion S1 by the water pressure onto the second surface Sb.
    Type: Application
    Filed: September 30, 2008
    Publication date: July 15, 2010
    Inventors: Takafumi Imaizumi, Fumihiko Kitagawa, Madoka Ito
  • Publication number: 20080118976
    Abstract: A colony (cell mass) proliferated under the undifferentiated state is obtained by using a carrier for cell culture in which two or more of a concavity having a porous body in a surface are arranged on a substrate surface in the form of a matrix, inoculating an undifferentiated cell on at least one concavity of the carrier for culture and carrying out culture.
    Type: Application
    Filed: November 19, 2007
    Publication date: May 22, 2008
    Inventors: Fumihiko KITAGAWA, Takafumi IMAIZUMI, Katsunori SASAKI
  • Publication number: 20070231884
    Abstract: According to a producing method including; preparing a foaming slurry by agitating and blending a dispersion medium containing hollow glass or ceramic particles having an average particle diameter of 1 ?m or more, a dispersant and a foaming agent to foam; obtaining a dried body by dropping the foaming slurry in liquid nitrogen, followed by freeze drying in a vacuum; and sintering the dried body to obtain a spherical porous body having open pores interconnected over an entirety, a porous body that is highly communicative, has sufficient mechanical strength and is suitable as a cell culture carrier for microcarrier culture can be provided.
    Type: Application
    Filed: April 3, 2007
    Publication date: October 4, 2007
    Inventors: Fumihiko Kitagawa, Takafumi Imaizumi
  • Publication number: 20070117204
    Abstract: A culture substrate made of ceramics of any one or more of titania, alumina, zirconia, yttria, and carbon is used where minute pores having a pore diameter of from 0.1 ?m to 10 ?m are provided at least for a place to which a cell is seeded, and an undifferentiated cell is seeded to at least one place of a surface of the culture substrate, whereby a culture substrate and a culture method for efficiently culturing the undifferentiated cell to be formed into a 3-dimensional cell block shape without causing immune rejection, and an undifferentiated cultured cell.
    Type: Application
    Filed: November 17, 2006
    Publication date: May 24, 2007
    Inventors: Fumihiko Kitagawa, Takafumi Imaizumi, Katsunori Sasaki
  • Patent number: 6210458
    Abstract: The gas filter module of the invention has: a housing which has a gas inlet port at one end and a gas outlet port at another end, and which is divided into two portions in a longitudinal direction; a filter body consisting of a porous ceramics member which is loaded into the housing and through which an inflow gas passes; and a ring-like support member consisting of dense ceramics which is fittingly coupled to a step portion formed inside the housing and which is joined to the filter body. The ring-like support member is fixed via two metal O-rings to a fixing gap of the step portion of the housing.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: April 3, 2001
    Assignee: Toshiba Ceramics Co., Ltd.
    Inventors: Toyohiko Shindo, Koichi Imura, Takafumi Imaizumi, Hiroyuki Ichikawa, Kazuyuki Ohshima, Takeshi Iwasaki