Patents by Inventor Takafumi Kitano

Takafumi Kitano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridyl-cyclohexanone compounds
    Patent number: 4845228
    Abstract: The present invention relates to cyclohexanone derivatives represented by general formula: ##STR1## wherein R represents a hydrogen atom or an acetyl group. The cyclohexanone derivatives are important intermediates for producing isoquinoline derivatives which are useful as drugs, especially for heart drugs.
    Type: Grant
    Filed: January 26, 1988
    Date of Patent: July 4, 1989
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Tsuneji Suzuki, Sannohe, Kunio, Toshihiko Ito, Masahiko Maruyama, Joji Kamiya, Makoto Hirayama, Takafumi Kitano, Akira Awaya
  • Isoquinoline derivative
    Patent number: 4824952
    Abstract: An isoquinoline derivative of the following formula: ##STR1## wherein R.sub.1 is a methyl or a methoxymethyl group and R.sub.2 and R.sub.3 are each a hydrogen atom or a methyl, ethyl, methoxy, a cyclohexyl, a phenyl, a 3,4-dimethoxyphenyl, a pyridyl or an oxo (.dbd.O) group;and therapeutically acceptable salts thereof which exhibit a low toxicity and a wide range of safety and are highly useful as a cardiotonic medication.
    Type: Grant
    Filed: July 12, 1985
    Date of Patent: April 25, 1989
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Tsuneji Suzuki, Kunio Sannohe, Toshihiko Ito, Masahiko Maruyama, Joji Kamiya, Makoto Hirayama, Takafumi Kitano, Akira Awaya
  • Method for the treatment of digestive ulcers
    Patent number: 4657896
    Abstract: DNAs, the salts thereof, the mixtures of DNA and RNA in which the DNA is mostly contained, and the mixtures of the salt of DNA and the salt of RNA in which the salt of DNA is mostly contained are used as active ingredients for pharmaceutical preparations for digestive ulcer, for example, DNA and RNA being obtained from BCG.
    Type: Grant
    Filed: May 17, 1984
    Date of Patent: April 14, 1987
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Osamu Yano, Takafumi Kitano
  • Isoquinoline derivatives
    Patent number: 4639521
    Abstract: Isoquinoline derivatives represented by the general formula (I): ##STR1## wherein R.sub.1 denotes a hydrogen or halogen atom, or a nitro or acetyl group, and R.sub.2 denotes a hydrogen atom, or a methyl, methoxy, phenyl, 4-pyridyl or 2-pyridyl group, and therapeutically acceptable salts thereof have high cardiotonic activity and low toxicity.
    Type: Grant
    Filed: June 20, 1986
    Date of Patent: January 27, 1987
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Kunio Sannohe, Kengo Otsuka, Toshohiko Ito, Masahiko Maruyama, Takafumi Kitano, Makoto Hirayama
  • Benzothiazine derivative
    Patent number: 4376768
    Abstract: N-(6-chloro-2-pyridyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-ca rboxamide 1,1-dioxide that is a novel benzothiazine derivative. The compound is characterized by a low degree of toxicity and a low incidence of gastric disorders and useful as an anti-inflammatory agent.
    Type: Grant
    Filed: June 16, 1981
    Date of Patent: March 15, 1983
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Shoichiro Ozaki, Hideya Kobayashi, Haruki Mori, Takafumi Kitano, Hiroshi Kawazura, Yutaka Okazaki
  • Benzothiazine derivative
    Patent number: 4376119
    Abstract: N-(6-fluoro-2-pyridyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-ca rboxamide 1,1-dioxide that is a novel benzothiazine derivative. The compound is characterized by a low degree of toxicity and a low incidence of gastric disorders and useful as an anti-inflammatory agent.
    Type: Grant
    Filed: June 16, 1981
    Date of Patent: March 8, 1983
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Shoichiro Ozaki, Hideya Kobayashi, Haruki Mori, Hiroshi Kawazura, Yutaka Okazaki, Takafumi Kitano, Mikio Kumakura, Takuo Nakano
  • Anti-ulcer pharmaceutical composition containing inositol hexasulfate aluminum or sodium aluminum salt as active ingredient
    Patent number: 4215143
    Abstract: Inositol hexasulfate aluminum and sodium aluminum salts have excellent anti-ulcer, antacid and antipeptic effects. Examination of the action of these compounds on various types of experimental gastric and duodenal ulcers in rats has shown that they have an excellent inhibitory effect on Shay's ulcer, acetic acid ulcer, stress ulcer, cysteamine duodenal ulcer, and aspirin ulcer. In addition, examination of the action of these compounds on the amount of gastric juice secreted, the acidity of gastric juice, and the activity of pepsin in rats has revealed their excellent antacid and antipeptic effects.
    Type: Grant
    Filed: September 7, 1978
    Date of Patent: July 29, 1980
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Zen-ichi Henmi, Akira Kotaki, Takafumi Kitano
  • Anti-ulcer pharmaceutical composition containing inositol hexasulfate or an alkaline metal salt thereof as active ingredient
    Patent number: 4207339
    Abstract: Inositol hexasulfate and its alkaline metal salts have excellent anti-ulcer, antacid and antipeptic effects.Examination of the action of these compounds on various types of experimental gastric and duodenal ulcers in rats has shown that they have an excellent inhibitory effect on Shay's ulcer, acetic acid ulcer, stress ulcer, cysteamine duodenal ulcer, and aspirin ulcer. In addition, examination of the action of these compounds on the amount of gastric juice secreted, the acidity of gastric juice, and the activity of pepsin in rats has revealed their excellent antacid and antipeptic effects.
    Type: Grant
    Filed: September 7, 1978
    Date of Patent: June 10, 1980
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Zen-ichi Henmi, Shuichi Arimoto, Akira Kotaki, Takafumi Kitano