Patents by Inventor Takafumi YOKOTA

Takafumi YOKOTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transplantation of mitochondria into lymphoid organ and composition therefor
    Patent number: 12268714
    Abstract: Provided herein are a method for isolation and transplantation of intact mitochondria to a lymphoid organ (a primary lymphoid tissue or a secondary lymphoid tissue), a composition of cells prepared by using a method described herein, and a method for manufacturing cells described herein. In particular, provided herein are methods of isolating intact mitochondria from a donor cell. Also provided herein are methods of transplanting mitochondria into a recipient cell. In some aspects, the methods can be performed in vivo. Further provided are a composition of cells that include the cells prepared using the methods of the present invention.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: April 8, 2025
    Assignee: LUCA Science Inc.
    Inventors: Masashi Suganuma, Hideyoshi Harashima, Yuma Yamada, Daisuke Sasaki, Takafumi Yokota
  • TRANSPLANTATION OF MITOCHONDRIA INTO LYMPHOID ORGAN AND COMPOSITION THEREFOR
    Publication number: 20220031743
    Abstract: Provided herein are a method for isolation and transplantation of intact mitochondria to a lymphoid organ (a primary lymphoid tissue or a secondary lymphoid tissue), a composition of cells prepared by using a method described herein, and a method for manufacturing cells described herein. In particular, provided herein are methods of isolating intact mitochondria from a donor cell. Also provided herein are methods of transplanting mitochondria into a recipient cell. In some aspects, the methods can be performed in vivo. Further provided are a composition of cells that include the cells prepared using the methods of the present invention.
    Type: Application
    Filed: September 13, 2019
    Publication date: February 3, 2022
    Applicant: LUCA Science Inc.
    Inventors: Masashi SUGANUMA, Hideyoshi HARASHIMA, Yuma YAMADA, Daisuke SASAKI, Takafumi YOKOTA