Patents by Inventor Takahiko Hariyama

Takahiko Hariyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230408511
    Abstract: An immunochromatography assay kit includes a specimen dropping portion to which a specimen is dropped, a conjugate portion to which a labeled antibody having a property of binding to a detection target in the specimen is immobilized, and a plurality of detection portions to which a capture antibody having a property of binding to the detection target is immobilized. The specimen dropping portion, the conjugate portion, and the plurality of detection portions are formed on a porous member. An outer shape of each detection portion is a dot shape.
    Type: Application
    Filed: November 2, 2021
    Publication date: December 21, 2023
    Inventors: Takahiko HARIYAMA, Hideya KAWASAKI, Hiroaki OHBA
  • Publication number: 20230258632
    Abstract: The present invention provides a highly sensitive immunochromatography measurement method in which a labeling substance for labeling an object to be detected in a specimen undergoing immunochromatography is quantified by being identified with precision, high resolution, and increased contrast using an electron microscope. An immunochromatography measurement method according to an embodiment of the present invention is characterized in that measurement is performed by an electron microscope after applying an auxiliary liquid other than a specimen in the immunochromatography.
    Type: Application
    Filed: April 8, 2021
    Publication date: August 17, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE, NANOSUIT INCORPORATED
    Inventors: Hideya KAWASAKI, Takahiko HARIYAMA
  • Publication number: 20220259518
    Abstract: The present invention provides an odorant composition having good palatability allowing peoples to feel comfortable using a small number of chemical compounds. An odorant composition according to an embodiment of the present invention consists of: when the total mass of ingredients contained in the odorant composition is 100.0% by mass, 40.0% by mass or more and 97.5% by mass or less of an ingredient (A) composed of aldehydes; 1.0% by mass or more and 20.0% by mass or less of an ingredient (B) composed of a ketone(s); and the balance being an ingredient (C) composed of a chemical compound(s) other than the ingredient (A) and the ingredient (B). The aldehydes of the ingredient (A) are: an essential ingredient (A1) composed of nonanal; and an optional ingredient (A2) selected from the group consisting of decanal, heptanal, octanal, benzaldehyde, undecanal, hexanal, and combinations thereof.
    Type: Application
    Filed: July 11, 2021
    Publication date: August 18, 2022
    Applicants: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE, NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY
    Inventors: Takahiko HARIYAMA, Mamiko OZAKI
  • Patent number: 11090240
    Abstract: The present invention relates to an ultraviolet reflecting agent composition or a water repellent agent composition, which contains at least one compound selected from among 2-pentacosanone, 2-heptacosanone, 2-nonacosanone, tetracosanal, hexacosanal, octacosanal and triacontanal.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: August 17, 2021
    Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TOKYO UNIVERSITY OF AGRICULTURE
    Inventors: Ryo Futahashi, Migaku Kawaguchi, Takahiko Hariyama, Yumi Yamahama, Daisuke Ishii, Shunsuke Yajima, Ryouka Miki, Naoki Mori
  • Publication number: 20200078280
    Abstract: The present invention relates to an ultraviolet reflecting agent composition or a water repellent agent composition, which contains at least one compound selected from among 2-pentacosanone, 2-heptacosanone, 2-nonacosanone, tetracosanal, hexacosanal, octacosanal and triacontanal.
    Type: Application
    Filed: November 20, 2019
    Publication date: March 12, 2020
    Applicants: National Institute of Advanced Industrial Science and Technology, Tokyo University of Agriculture
    Inventors: Ryo Futahashi, Migaku Kawaguchi, Takahiko Hariyama, Yumi Yamahama, Daisuke Ishii, Shunsuke Yajima, Ryouka Miki, Naoki Mori
  • Patent number: 10352527
    Abstract: Provided is a luminous, apparatus such as a display, having a function of preventing attraction of insects. A display apparatus 1 has a light emission surface 1 whose peripheral edge region is at least partially formed as a low-attraction region which is less capable of attracting bugs, wherein the low-attraction region is composed of an optical property gradient region whose at least one optical property gradually changes in a direction from an inward side to an outward side of the light emission surface.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: July 16, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Yoshihiro Uozu, Takahiko Hariyama, Mantaro Hironaka
  • Patent number: 10258982
    Abstract: A combined-blade open flow path device is a fluid flow path device where flow paths are adjacent to each other. The combined-blade open flow path device comprises a substrate configured to constitute a bottom portion of the flow paths; and blades erected on a surface of the substrate, the blades being configured to constitute side walls of the flow paths, wherein the blades are erected in groups, each of the groups extending from an upstream side to a downstream side in a flow direction of a fluid with a space between each of the blades in the flow direction of the fluid in each of the groups for making conduction of the fluid between the adjacent flow paths possible, and wherein one end of one of the flow paths is configured to be in contact with the fluid and is configured to make a flow of the fluid possible.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: April 16, 2019
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko Hariyama, Daisuke Ishii, Masatsugu Shimomura, Ko Okumura, Marie Tani
  • Patent number: 10128078
    Abstract: Provided are a protective agent for electron microscopic observation in a vacuum which can protect a biological sample in a water-containing state, such as a mammal, a plant tissue or a cultured cell, and a single cell in the living state without deforming it even in a vacuum, a kit using the same, methods for observation, diagnosis, evaluation, and quantification of a sample by an electron microscope, and a sample stage to be used for the observation. The protective agent for electron microscopic observation of the present invention contains a a component to impart the survival environment, a saccharide, and an electrolyte.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: November 13, 2018
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Satoshi Hirakawa, Hideaki Kawasaki, Masatsugu Shimomura, Daisuke Ishii, Isao Ohta, Yoshinori Muranaka
  • Patent number: 10051851
    Abstract: By plates (31, 32) having different colors, an edge is formed in the vertical direction along the boundary between the plates (31, 32). Further, as materials of the plates (31, 32), a material which primarily transmits ultraviolet light having a wavelength of about 370 nm and a material which primarily transmits green light having a wavelength of about 520 nm are used. This constitution makes an attraction device (10) capable of attracting insect pests more efficiently as compared to a case where a light source such as a mercury lamp which emits a large amount of light having a wavelength of 300 to 600 nm or an LED which emits a large amount of light having a relatively short wavelength is used.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: August 21, 2018
    Assignee: HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Takahiko Hariyama, Mantaro Hironaka
  • Patent number: 10046283
    Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 14, 2018
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Masatsugu Shimomura, Daisuke Ishii, Isao Ohta, Yoshinori Muranaka
  • Publication number: 20170282130
    Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 5, 2017
    Inventors: Takahiko HARIYAMA, Yasuharu TAKAKU, Hiroshi SUZUKI, Masatsugu SHIMOMURA, Daisuke ISHII, Isao OHTA, Yoshinori MURANAKA
  • Patent number: 9687793
    Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: June 27, 2017
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Masatsugu Shimomura, Daisuke Ishii, Isao Ohta, Yoshinori Muranaka
  • Publication number: 20170044002
    Abstract: A combined-blade-type open flow path device being a fluid flow path device where a plurality of flow paths are adjacent to each other, the combined-blade-type open flow path device comprising: a substrate configured to constitute a bottom portion of the flow paths; and a plurality of blades erected on a surface of the substrate, the plurality of blades configured to constitute side walls of the flow paths, wherein the plurality of blades are erected in a plurality of numbers at a space in a direction from an upstream side to a downstream side of a flow of the fluid, and conduction of the fluid between the flow paths adjacent at the space is made possible, and wherein the flow of the fluid is made possible by one end of the flow path being in contact with the fluid.
    Type: Application
    Filed: April 22, 2015
    Publication date: February 16, 2017
    Applicant: Japan Science And Technology Agency
    Inventors: Takahiko HARIYAMA, Daisuke ISHII, Masatsugu SHIMOMURA, Ko OKUMURA, Marie TANI
  • Patent number: 9557253
    Abstract: Provided is an observation method by an electron microscope, in which a biological sample can be observed as it is alive and a situation that the biological sample is moving can be observed using an electron microscope, and a composition for evaporation suppression under vacuum, a scanning electron microscope, and a transmission electron microscope used in the method. The sample observation method by an electron microscope according to the invention includes applying a composition for evaporation suppression containing at least one kind selected from an amphiphilic compound, oils and fats, and an ionic liquid to the surface of a sample to form a thin film, and covering the sample with the thin film, and displaying an electron microscopic image of the sample, which is covered with the thin film and accommodated in a sample chamber under vacuum, on a display device.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: January 31, 2017
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Yoshinori Muranaka, Isao Ohta, Masatsugu Shimomura, Daisuke Ishii
  • Publication number: 20160343539
    Abstract: Provided are a protective agent for electron microscopic observation in a vacuum which can protect a biological sample in a water-containing state, such as a mammal, a plant tissue or a cultured cell, and a single cell in the living state without deforming it even in a vacuum, a kit using the same, methods for observation, diagnosis, evaluation, and quantification of a sample by an electron microscope, and a sample stage to be used for the observation. The protective agent for electron microscopic observation of the present invention contains a a component to impart the survival environment, a saccharide, and an electrolyte.
    Type: Application
    Filed: January 28, 2015
    Publication date: November 24, 2016
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko HARIYAMA, Yasuharu TAKAKU, Hiroshi SUZUKI, Satoshi HIRAKAWA, Hideaki KAWASAKI, Masatsugu SHIMOMURA, Daisuke ISHII, Isao OHTA, Yoshinori MURANAKA
  • Publication number: 20160010827
    Abstract: Provided is a luminous, apparatus such as a display, having a function of preventing attraction of insects. A display apparatus 1 has a light emission surface 1 whose peripheral edge region is at least partially formed as a low-attraction region which is less capable of attracting bugs, wherein the low-attraction region is composed of an optical property gradient region whose at least one optical property gradually changes in a direction from an inward side to an outward side of the light emission surface.
    Type: Application
    Filed: September 18, 2015
    Publication date: January 14, 2016
    Inventors: Yoshihiro UOZU, Takahiko HARIYAMA, Mantaro HIRONAKA
  • Publication number: 20150224452
    Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.
    Type: Application
    Filed: September 6, 2013
    Publication date: August 13, 2015
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Masatsugu Shimomura, Daisuke Ishii, Isao Ohta, Yoshinori Muranaka
  • Publication number: 20140227734
    Abstract: Provided is an observation method by an electron microscope, in which a biological sample can be observed as it is alive and a situation that the biological sample is moving can be observed using an electron microscope, and a composition for evaporation suppression under vacuum, a scanning electron microscope, and a transmission electron microscope used in the method. The sample observation method by an electron microscope according to the invention includes applying a composition for evaporation suppression containing at least one kind selected from an amphiphilic compound, oils and fats, and an ionic liquid to the surface of a sample to form a thin film, and covering the sample with the thin film, and displaying an electron microscopic image of the sample, which is covered with the thin film and accommodated in a sample chamber under vacuum, on a display device.
    Type: Application
    Filed: September 7, 2012
    Publication date: August 14, 2014
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Yoshinori Muranaka, Isao Ohta, Masatsugu Shimomura, Daisuke Ishii
  • Publication number: 20140223803
    Abstract: By plates (31, 32) having different colors, an edge is formed in the vertical direction along the boundary between the plates (31, 32). Further, as materials of the plates (31, 32), a material which primarily transmits ultraviolet light having a wavelength of about 370 nm and a material which primarily transmits green light having a wavelength of about 520 nm are used. This constitution makes an attraction device (10) capable of attracting insect pests more efficiently as compared to a case where a light source such as a mercury lamp which emits a large amount of light having a wavelength of 300 to 600 nm or an LED which emits a large amount of light having a relatively short wavelength is used.
    Type: Application
    Filed: September 20, 2012
    Publication date: August 14, 2014
    Applicant: HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Takahiko Hariyama, Mantaro Hironaka