Patents by Inventor Takahiro AOTO

Takahiro AOTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC MEDICINE FOR FIBROUS DISEASE
    Publication number: 20200038486
    Abstract: The present inventors discovered that an HMGB1 fragment peptide having a particular amino acid sequence exhibits effects of inhibiting finger adhesion and digestive tract scarring and prolonging survival in the dystrophic epidermolysis bullosa model mice. Also in the skin ulcer model, administration of the specific HMGB1 fragment peptide was found to inhibit the fibrosing of skin during the healing process of the ulcer. Based on these findings, the present application provides pharmaceutical compositions for the treatment of fibrotic diseases, which comprise the specific HMGB1 fragment peptide.
    Type: Application
    Filed: April 6, 2018
    Publication date: February 6, 2020
    Inventors: Katsuto TAMAI, Takahiro AOTO, Sho YAMAZAKI, Takehiko YAMAZAKI
  • THERAPEUTIC AGENT FOR CEREBRAL INFARCTION
    Publication number: 20190358307
    Abstract: The purpose of the present invention is to provide a novel medicine that is effective in treating cerebral infarction. The present invention provides a pharmaceutical composition that contains a peptidyl-prolyl cis-trans isomerase B (PPIB) protein, a nucleic acid encoding the PPIB protein, or a cell that secretes the PPIB protein.
    Type: Application
    Filed: November 9, 2017
    Publication date: November 28, 2019
    Applicants: STEMRIM INC., OSAKA UNIVERSITY
    Inventors: Katsuto TAMAI, Takehiko YAMAZAKI, Koichi YOKOTA, Takahiro AOTO